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Pharm Emerg Med

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Question
Answer
treatment priorities for sepsis   oxygen, aggressive fluid replacement, vasopressors (dopamine, dobutamine, norepi, vasopressin)  
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empiric broad spectrum antibiotics used in sepsis   3rd gen cephalosporins + aminoglycoside (ceftazidime and gentamycin), +/- vancomycin (MRSA)/clindamycin (anerobes)  
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recombinant human activated protein C, only FDA approved drug used solely for the treatment of sepsis in the adult patient with high risk of death. only for use in the ICU   Xigris  
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empiric treatment for bacterial meningitis   begin antibiotics immediately (ceftriaxone or cefotoaxime 2 g IV and vanc. add ampicillin for pts <3months/>55 and or immunocomp  
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what do you add to empiric therapy for meningitis if HSV is suspected   acyclovir  
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what do you give concurrently with empiric antibiotics when treating bacterial meningitis   dexamethasone, continue for 4 days  
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supportive care for bacterial meningitis   hydration, pain meds, anticonv, antiemetics  
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outpatient antibiotics for pneumonia   azithro, doxy, levo, cefpodoxime+azithro  
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inpatient regimens for pneumonia   ceftriaxone+azithro, resp fluoroq, +/- vanc  
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Duration of tx for uncomplicated cystitis in non-pregnant women/men   3-5 days  
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what is the duration of treatment for uncomplicated cystitis in children, preg women, and complicated infections in everyone else   7-10 days  
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antibiotics for cystitis   tmp/smz, nitrofurantoin, quinolones, cephalexin  
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treatment for pyelonephritis   cipro 7-10 days, levo for 7 days, augmentin 10 days, cephalexin 10 days  
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treatment of impetigo   cephalexin, diclox, mupirocin, retapamulin  
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outpatient treatment for cellulitis   cephalexin, diclox, augmentin, doxy, minocycline, (MRSA-tmp/smx-bactrim or clinda  
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inpatient treatment for cellulitis   IV clinda, IV vanc +/- cefazolin  
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treatment of a fresh bite <24 hours old   exploration/irrigation/immobilization, primary closure if face/head/neck, tetanus/rabies prophylaxis  
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prophylactic antibiotics for fresh bite   augmentin, moxifloxacin, clindamycin + ciprofloxacin  
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incubation of malaria in returning travelers   varies from <2 weeks to >6 weeks  
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PID tx   ceftriaxone + azithromycin OR doxycycline + metronidazole (outpatient)  
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Chancroid tx   Ceftriaxone or zithro (1 dose)  
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meningitis bugs: neonates   GBS, E coli, listeria; tx = amp & cefotaxime (Claforan)  
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meningitis bugs: 1 mo - 50 yo   SP, Neisseria, H flu  
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meningitis bugs: >50 yo / EtOH   SP, listeria; tx = amp + rocephin + dex  
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meningitis tx: 1 - 3 mos   Amp + (rocephin or cefotaxime) + Dex  
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meningitis tx: 3 mos - 50 yo   (rocephin or cefotaxime) + vanc + Dex  
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PEP for meningitis   post exposure prophylaxis = rifampin for household contacts/droplet exp only; alts = cipro or rocephin  
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Created by: Abarnard
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