Alcohol and Street Drugs
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| Inheritance of addition: Male children to develop alcoholism | 25% risk
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| Inheritance of addition: Female children to develop alcoholism | 5-10% risk
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| How many children each year are born with FAS in the US? | 4000
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| Two methods to screen pregnant women for alcohol use... | 1. Laboratory tests 2. Brief questionnaires
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| 4 P's for assessment of risk drinking | Pregnancy, Past, Partner, Parents
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| NET | Normal drinker? Do you ever have an EYE-opener? How many drinks does it TAKE to make you feel high?
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| Laboratory tests for disk drinking | liver damage, increased MCV, urine toxicology
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| Alcohol can lead to... | Pregnancy loss, FAS (Growth retardation, CNS dysfunction, facial features, malformations)
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| CNS abnormalities with FAS | below average intelligence, hyperactivity, attention deficits, language dysfunction, perceptual difficulties
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| Tobacco... increased risk for | IUGR, prematurity, stillbirth; facial clefts, learning disorders, hyperactivitiy,
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| Postnatal exposure to Tobacco... | SIDS, asthma, ear infections
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| The possibility of substance abuse must be considered in ... | ALL pregnant women.
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| Cocaine and pregnancy... | vasoconstrictive and hypertensive activity ; OB complications ; IUGR, small risk for malformations (GI, cardiovascular)
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| Cocaine... | neonatal behavioral abnormalities (disappear in the first few months of life), long term impact on cognition and behavior not well understood; SIDS;
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| When cocaine is excreted in breast milk... | reports of vomiting, tremulousness, irritability, and seizures
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| Marijuana.... what is excreted in breastmilk? | THC
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| Some evidence that marijuana causes... | behavioral changes
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| Marijuana use in the 3rd trimester can cause... | adaptation syndrome
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| Amphetamines & studies | animal & human studies are inconsistent
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| Amphetamines & 3rd trimester use... | low birth wt, prematurity, withdrawal symptoms, possible long term effect on cognition and behavior
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| LSD (prior use, chromosomal damage?) | Not associated with increased risk for abnormalities in subsequent pregnancies and does not appear to cause chromosome damage
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| LSD case reports of ... | CNS, eyes, limbs, not most studies have not substantiated this
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| Heroin | long term behavioral abnormalities, increased risk for OB complications including IUGR, prematurity, fetal distress, perinatal mortality, SIDS, neonatal withdrawal
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| Inhalation of solvents | fetal damage similar to that seen with FAS (preterm labor, growth deficiency, microcephaly and CNS dysfunction, facial features)
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Created by:
KChatham
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