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Psychiatric Meds

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
Maternal prenatal stress/depression is associated with..   low infant birth weight and prematurity, also temperament and behavior  
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Women with schizophrenia or a major affective disorder have an increased risk for...   fetal distress, abruptio placenta, IUGR, and babies with heart defects  
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When compaired to babies whose mothers were depressed but took no meds, babies exposed to SSRIs had...   lower birth weight, gestational age, respiratory distress, jaundice and feeding problems  
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Antidepressants and pregnancy: SSRIs (and tricyclics)   Low risk for malformations, risk for problems in newborn period  
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Antidepressants and pregnancy: Paxil   small increase risk for heart defects (~1%), significant problems for newborn adaptation  
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Antidepressants and pregnancy: Effexor   significant problems with newborn adaptation  
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Antidepressants and pregnancy is a...   continued area of study, risk is unlikely to be large but unlikely to be zero  
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SSRIs and neonatal adaption: neonatal behaviorial syndrome   CNS (Irritability and agitation), Motor (tremors, increased muscle tone), respiratory distress, GI difficulties, onset between birth and 3 weeks and typically lasts less than two weeks  
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Neonatal behaviorial syndrome most implicated with what 3 drugs   Paxil, Prozac and Effexor  
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Medical management for Neonatal adaptation syndrome   Supportive care in the NICU, toxicity versus withdrawal.. occasionally small doses of the maternal medication are administered  
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FDA says (with SSRIs) 3rd trimester exposure leads to...   20-30% risk for neonatal behavioral syndrome and 1% risk for PPHN  
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Lithium   (~1%) risk for Ebstein's anomaly, fetal echocardiogram at 20 weeks is recommended. 3rd trimester has been associated with LOTS OF stuff...  
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Lithium in 3rd trimester...   neonatal cyanosis, hypotonia, cardiac rhythm disturbances, diabetes insipidus and hypothyroidism  
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Antipsychotics: Haldol   limb defects, extrapyramidal effects in third trimester  
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Antipsychotics: Risperdal   Reassuring!!!!  
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Antipscyhotics: Zyprexa   Reassuring. But maternal weight gain may lead to OB complications  
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Infants and breastfeeding: Long term effects of psychotropics on neurocognitive development are...   largely unknown  
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Infants and breastfeeding: Potential acute efects of SSRIs on infants    
🗑
Maternal prenatal stress/depression is associated with..   low infant birth weight and prematurity, also temperament and behavior  
🗑
Women with schizophrenia or a major affective disorder have an increased risk for...   fetal distress, abruptio placenta, IUGR, and babies with heart defects  
🗑
When compaired to babies whose mothers were depressed but took no meds, babies exposed to SSRIs had...   lower birth weight, gestational age, respiratory distress, jaundice and feeding problems  
🗑
Antidepressants and pregnancy: SSRIs (and tricyclics)   Low risk for malformations, risk for problems in newborn period  
🗑
Antidepressants and pregnancy: Paxil   small increase risk for heart defects (~1%), significant problems for newborn adaptation  
🗑
Antidepressants and pregnancy: Effexor   significant problems with newborn adaptation  
🗑
Antidepressants and pregnancy is a...   continued area of study, risk is unlikely to be large but unlikely to be zero  
🗑
SSRIs and neonatal adaption: neonatal behaviorial syndrome   CNS (Irritability and agitation), Motor (tremors, increased muscle tone), respiratory distress, GI difficulties, onset between birth and 3 weeks and typically lasts less than two weeks  
🗑
Neonatal behaviorial syndrome most implicated with what 3 drugs   Paxil, Prozac and Effexor  
🗑
Medical management for Neonatal adaptation syndrome   Supportive care in the NICU, toxicity versus withdrawal.. occasionally small doses of the maternal medication are administered  
🗑
FDA says (with SSRIs) 3rd trimester exposure leads to...   20-30% risk for neonatal behavioral syndrome and 1% risk for PPHN  
🗑
Lithium   (~1%) risk for Ebstein's anomaly, fetal echocardiogram at 20 weeks is recommended. 3rd trimester has been associated with LOTS OF stuff...  
🗑
Lithium in 3rd trimester...   neonatal cyanosis, hypotonia, cardiac rhythm disturbances, diabetes insipidus and hypothyroidism  
🗑
Antipsychotics: Haldol   limb defects, extrapyramidal effects in third trimester  
🗑
Antipsychotics: Risperdal   Reassuring!!!!  
🗑
Antipscyhotics: Zyprexa   Reassuring. But maternal weight gain may lead to OB complications  
🗑
Infants and breastfeeding: Long term effects of psychotropics on neurocognitive development are...   largely unknown  
🗑
Infants and breastfeeding: Potential acute efects of SSRIs on infants   GI Disturbances (Prozac), irritability, somnolence  
🗑
Potential long term effects of SSRIs while breastfeeding   Neurobehavioral changes, decreased wt gain  
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Mood stabilizers   American Academy of Pediatrics classifies lithium as not compatible with breastfeeding  
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