Renal histology lectures 1 and 2
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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Filtration barrier | fenestrations of glomerular capillaries, fused basement membrane, filtration slits
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Juxtaglomerular apparatus | Extraglomerular mesangial cells, macula densa (modified DCT), granular/juxtaglomerular cells (modified SM of affarent arteriole)
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Parietal layer of Bowmann's capsule | simple squamous
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PCT (convoluted portion) | simple cuboidal, brush border (reabsorption), basolateral interdigitations (Na+ transport out), mitochondria (active transport)
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Pars Recta (thick descending limb) | brush border (secretion of organic acids), no basolateral interdigitations, mitochondria (active transport)
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Thin limbs | simple squamous
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Thick ascending limb | simple cuboidal, no brush border, basolateral interdigitations (Na+ transport), mitochondria (active transport), Tomm-Horsfall protein production
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Distal convoluted tubule | simple cuboidal, no brush border, basolateral interdigitations (Na+ transport), mitochondria (active transport)
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Collecting tubule cell types | principal cells + intercalated cells + DCT cells
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Collecting tubule histocytology | simple cuboidal, intercalated have darker staining and brush border remnant
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Principal cell function | Na+ reabsorption, K+ secretion, H2O reabsorption (ADH mediated)
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Intercalated cell function | Acid-base balance
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Collecting duct cell types | principal cells + intercalated cels
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Collecting duct histocytology | simple columnar
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Vasa recta | simple squamous with RBCs inside (if not washed out)
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Ureters | transitional epithelium, lamina propria, circular/longitduinal SM, adventitia
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Transitional epithelium details | stratified with mature surface cells which are cuboidal/columnar called umbrella cells
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Umbrella cell surface | inflexible plaques with surface vesicle invaginations in between
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Bladder histology | transitional epithelium, lamina propria, circular/longitudinal/circular SM, adventitia
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Prostatic urethra | transitional epithelium (continuation of bladder)
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Membranous urethra | psuedostratified columnar
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Spongy urethra | stratified columnar/squamous
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Created by:
skyglow1
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