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Renal histology lectures 1 and 2

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Question
Answer
Filtration barrier   fenestrations of glomerular capillaries, fused basement membrane, filtration slits  
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Juxtaglomerular apparatus   Extraglomerular mesangial cells, macula densa (modified DCT), granular/juxtaglomerular cells (modified SM of affarent arteriole)  
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Parietal layer of Bowmann's capsule   simple squamous  
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PCT (convoluted portion)   simple cuboidal, brush border (reabsorption), basolateral interdigitations (Na+ transport out), mitochondria (active transport)  
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Pars Recta (thick descending limb)   brush border (secretion of organic acids), no basolateral interdigitations, mitochondria (active transport)  
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Thin limbs   simple squamous  
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Thick ascending limb   simple cuboidal, no brush border, basolateral interdigitations (Na+ transport), mitochondria (active transport), Tomm-Horsfall protein production  
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Distal convoluted tubule   simple cuboidal, no brush border, basolateral interdigitations (Na+ transport), mitochondria (active transport)  
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Collecting tubule cell types   principal cells + intercalated cells + DCT cells  
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Collecting tubule histocytology   simple cuboidal, intercalated have darker staining and brush border remnant  
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Principal cell function   Na+ reabsorption, K+ secretion, H2O reabsorption (ADH mediated)  
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Intercalated cell function   Acid-base balance  
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Collecting duct cell types   principal cells + intercalated cels  
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Collecting duct histocytology   simple columnar  
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Vasa recta   simple squamous with RBCs inside (if not washed out)  
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Ureters   transitional epithelium, lamina propria, circular/longitduinal SM, adventitia  
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Transitional epithelium details   stratified with mature surface cells which are cuboidal/columnar called umbrella cells  
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Umbrella cell surface   inflexible plaques with surface vesicle invaginations in between  
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Bladder histology   transitional epithelium, lamina propria, circular/longitudinal/circular SM, adventitia  
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Prostatic urethra   transitional epithelium (continuation of bladder)  
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Membranous urethra   psuedostratified columnar  
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Spongy urethra   stratified columnar/squamous  
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Created by: skyglow1
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