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CM- GI -4- PUD

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Question
Answer
What is ulceration of duodenum or stomach   Peptic Ulcer Disease  
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Patient presents with epigastric pain, nausea, vomiting and variable blood in vomitus and self limited inflammation of gastric mucosa what condition are they suffering from   Acute Gastritis  
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What are common cuases of acute gastritis   Aspirin and NSAIDS, Alcohol, Acid and Alkali ingestion, Stress, Shock related mucosal ischemia, Sepsis  
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How does ETOH contribute to Gastric erosions   Stimulates over secretion of HCL  
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How does aspirin and other NSAIDS contribute to gastric erosions   inhibit local synthesis of prostaglandins weakening mucosal defense system  
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How does shock contribute to gastric erosion   hypoprofusion results in increased susceptibility of mucosal cells to acid  
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What type of gastric stress ulcer is caused by brain injury   Cushing ulcer  
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What type of gastric stress ulcer is caused by burns   Curling ulcer  
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What are the 3 main types of non erosive gastritis   Chronic Type A, Chronic Type B, hypertrophic gastritis  
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What type of chronic gastritis is caused by autoimmune disease and has a higher risk of gastric adenocarcinoma   Chronic Type A gastritis  
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What type of chronic gastritis is caused by H. Pylori and increases your chance of adenocarcinoma and lymphoma   Chronic Type B gastritis  
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What happens in late stages of chronic type a and B gastritis   atrophy of gastric glands, intenstinal metaplasia, lymphocytic follicles in the mucosa  
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What is the number one infectious cause of PUD in the duodenum and gastric types   H. Pylori  
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How does H. Pylori cause PUD   induces an intense inflammatory and immune response causes mucosal injury  
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Which type of ulcer is more common gastric or duodenal   Duodenal 4:1 over gastric ulcers  
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Patient presests with PUD which doesn't respond to usual treatment what is the likely cause of their ulcers   zollinger-ellison syndrome a gastrin secreting tumor causing hyper acidity and ulceration  
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How can you tell a peptic ulcer from an adenocarcinoma   smooth edges will indicate an ulcer rather than adenocarcinoma  
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Patient presents with s/sx of PUD you order an endoscopy and notice a small 1-2 cm diameter lesions with smooth sides and bottom. Borders are sharp what is the likely cause   Peptic Ulcer  
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What is the most common complication from a peptic ulcer   hemorrhage- look for melena and iron deficiency anemia  
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What other complications can arise from peptic ulcer disease besides hemorrhage   Perforation, Stenosis and obstruction, penetration into pancrease  
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What is the most common malignancy of the stomach and what is the 5 yr survival rate   Adenocarcinoma- 5yr survival rate is 20%  
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Where is the most likely place to find gastric cancer   Pylorus and pyloric antrum  
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Patient is 30yrs old and presents complaining of s/sx of PUD based on what you know about PUD where is there ulcer most likely located   Duodenal Ulcer- they are the most common and occur 25-75yrs. Gastric ulcers occur 55-65 yrs  
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What are the s/sx of PUD   Clusters of pain gnawing, dull, aching hunger like pain in epigastric area  
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Patient complains of gnawing dull aching hunger like pain in epigastric area that is relieved by eating what is likely causing their symptoms be specific include location   PUD in duodenal area pain can be relieved by eating and antacids. Gastric ulcers typically not relieved by food.  
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You are working up a patient for PUD and why would you order a UGI (upper gastroinetsinal contrast series) over a endoscopy   Is is less invasive, expensive and is 90% accurate when using double contrast. Endoscopy is invasive and expensive but more accurate  
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What tests could you order to confirm PUD caused by H. Pylori   Urea Breath test, Stool antigen test, specific antibody test or endoscopic bx  
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What treatments will you order for PUD   H2 blockers, PPI and if it is caused by H. Pylori add 2 antibiotics may need to step it up to quadruple therapy  
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