MedMicro 2006 UTHSCmed
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each of the black spaces below before clicking
on it to display the answer.
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| Chlamydia trachomatis Shapeq | Small bacillus
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| Chlamydia trachomatis Aerobicity | Aerobic
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| Chlamydia trachomatis Motility | nonmotile, no pili
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| Chlamydia trachomatis Pathophysiology | Life cycle: EB infects, RB divides
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| Chlamydia trachomatis reservoir | Humans
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| Chlamydia trachomatis Diseases | STD's, Trachoma (eyes), LGV, PID; cna be asymptomatic in women
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| Chlamydia trachomatis Specimen | Exudate
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| Chlamydia trachomatis Bab Diagnosis | giemsa stain, specific culture, DNA probe, serology, PCR (best one)
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| Chlamydia trachomatis Treatment | Azithromycin(one dose), doxycycline(2 wks), clarithromycin (kids, 95% efficacy), Erythromycin(neonates and children)
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| Chlamydia trachomatis Prevention/Control | Safe sex, screening, notify partners, abstinence
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| Chlamydia trachomatis NOTES: | Leading preventable cause of blindness, #1 STD in US, Obligate intracellular anaerobe, No peptidoglycan cell wall
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| C. psittaci Shape | Small bacillus
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| C. psittaci Aerobicity | Aerobic
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| C. psittaci Motility | Non-motile, no pili
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| C. psittaci Reservoir | Birds, animals
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| C. psittaci Diseases | Parrot fever, pneumonia, complications
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| C. psittaci Lab diagnosis | Giemsa stain, DNA prbe, PCR, serology
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| C. psittaci Treatment | Axithromycin, Doxycycline
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| C. psittaci Prevention | Care with bird wast
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| C. psittaci NOTES: | Obligate intracellular parasite, No peptidoglycan in cell wall
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| C. pneumoniae Shape | Small bacillus
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| C. pneumoniae Aerobicity | Aerobic
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| C. pneumoniae Motility | NON-motile, no pili
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| C. pneumoniae Reservoir | Humans
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| C. pneumoniae Diseases | Pneumonia, atherosclerosis
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| C. pneumoniae Lab Diagnosis | Giemsa stain, DNA probe, PCR, serology
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| C. pneumoniae Treatment | Axithromycin
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| C. pneumoniae NOTES: | Obligate intracellular parasite, No peptidoglycan in cell wall
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| Chlamydiae | Originally thought to be viruses, but are not: Gram (-) cell envelope, contain DNA and RNA, ribosomes, susceptible to antibiotics, make own proteins, nucleic acids, lipids
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| General Properties: Chlamydiae | Obligate intracellular parasites, Very small, Not culturable outside host cell, no peptidoglycan in the cell wall, NON-motile, nonpiliated, (All these same as viruses)
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| Why are Chlamydiae Bacteria? | Gram (-) cell envelope, has DNA & RNA, has prokaryotic ribosomes, Synthesizes its own protein, nucleic acids, lipids, Susceptible to several antibodies.
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| Why Chlamydiae and NOT Rickettsia? | No cytochromes, No ATP, Don't require arthropods for transmission
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| EB (elementary body) | Small(.2-.4 mM diameter), extracellular, metaboically inactive, cannot proliferate, infectious
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| RB (reticular body) | .6-1.0 mM diameter, intracellular, metabolically active, divides by binary fission, noninfectious
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