MedMicro 2006 UTHSCmed
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| Treponema pallidum Shape | helical bacillus (long and thin)
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| Treponema pallidum aerobicity | microaerophilic
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| Treponema pallidum motility | peroplasmic flagella, cork-screw
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| Treponema pallidum Reservoir | Humans
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| Treponema pallidum diseases | Syphilis
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| Treponema pallidum specimen | exudate from skin
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| Treponema pallidum lab diagnosis | Darkfield microscopy, non- & triponemal tests, characteristic lesions
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| Treponema pallidum treatment | penicillin (in secondary, can cause Jarisch Herxheimer reaction:fever, chills)
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| Treponema pallidum prevention/control | safe sex!, screening of pregnant women
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| Treponema pallidum NOTES: | obligate parasite of humans
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| Treponema pallidum Neurosyphilis | mental illness, shuffling gate
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| Treponema pallidum LATE congenital syphilis | Hutchinson's teeth (notched incisors) and interstitial keratitis (cloudy eye)
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| T. pallidum pertenue = | Yaws
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| T. carateum = | Pinta
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| T. vincenti & denticola = | Dental Caries
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| T. pallidum endemicum = | endemic syphilis
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| Brachuspira pilosicoli = | gut flora?
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| B. hyodysenteriae = | dysentery in pigs
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| Borrelia recurrentis & hermsiiShape | Helical bacillus
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| Borrelia recurrentis & hermsii Aerobicity | microaerophilic
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| Borrelia recurrentis & hermsii Motility | flagella
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| Borrelia recurrentis & hermsii virulence factors | Variable Major Protein: antigenic variants cause cycles/relapses
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| Borrelia recurrentis & hermsii reservoir | rodents + ticks, humans + lice
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| Borrelia recurrentis & hermsii specimen | Blood
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| Borrelia recurrentis & hermsii NOTES: | mimics: leptospirosis, typhus, typhoid fever, and malaria
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| B. burgdoferi shape | Helical bacillus
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| B. burgdoferi aerobicity | microaerophilic
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| B. burgdoferi motility | highly motile
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| B. burgdoferi reservoir | Mouse, deer + tick
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| B. burgdoferi specimen | serum, skin biopsy
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| B. burgdoferi lab diagnosis | serology (most), culture (rare), PCR (rare)
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| B. burgdoferi treatment | Ter/doxycycline (early); ceftriaxone, penicillin (late), amoxicillin (both)
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| B. burgdoferi prevention/control | DEET, white socks over pants, avoidance
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| B. burgdoferi NOTES: | promary erythemia migrans from wound site, secondary cardio/neuro/opthalmo, terthiary chronic (arthritis, dermititis)
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| Leptospira interrogans shape | Helical bacillus
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| Leptospira interrogans aerobicity | Aerobe
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| Leptospira interrogans Temperature | 30 C
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| Leptospira interrogans reservoir | mammals: urine
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| Leptospira interrogans diseases | leptospirosis: rash, fever, shiclls, in stages; rare Weil's syndrome
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| Leptospira interrogans specimen | blood, CSF, urine
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| Leptospira interrogans treatment | no standard: doxycycline, Beta-lactams, streptomycin
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| Leptospira interrogans prevention/control | Avoid urine or contaminated water
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| Primary syphilis | Chanchre
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| Secondary syphilis | Rash
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| Terthiary syphilis | latent, neuro, gummatour, or cardio; congenital (severe)
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