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NUHS PHYS CH3

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Question
Answer
cell containing a membrane-enclosed nucleus with genetic material; plant and animal cells   Eukaryotic cell  
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Cells such as bacteria that do not contain their genetic info w/in a membrane-enclosed nucleus   Prokaryotic cell  
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Membrane that forms outer surface of cell and separates cell's contents from extracellular fluid   Plasma membrane  
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membrane bound compartment, along with some particles and filaments that perform specialized functions in cell   Cell Organelles  
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large membrane bound organelle that contains cell's DNA; primary function is the storage & transmission of the genetic info to the next generation of cells   Nucleus  
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region of cell interior outside of nucleus   Cytoplasm  
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Intracellular fluid that surrounds cell organelles and nucleus   Cytosol  
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performs a variety of functions, but most universal is to provide a selective barrier to the passage of molecules   Membranes  
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major component of cell membranes; this lipid is a Amphipathic molecule   Phospholipids  
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protein embedded in membrane lipid layer; may span entire membrane or be located at only one side   Integral membrane protein  
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hydrophilic proteins associated w/ cytoplasmic surface in the interior of the membrane   Peripheral membrane proteins  
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integral protein that spans the plasma membrane; often acts as a receptor or ion channel   Transmembrane protein  
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transmembrane protein in plasma membrane; binds to specific proteins in extracellular matrix and on adjacent cells to help organize cells into tissues   Integrins  
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junction that holds two cells together; consists of plasma membranes junction of adjacent cells linked by fibers. hold adjacent cells firmly together in areas that are subject to considerable stretching, such as skin   Desmosomes  
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membrane junction in which extracellular surfaces of the plasma membrane of 2 adjacent cells are joined together so that no extracellular space remains between them and restricts molecule diffusion through space between cells   Tight junctions  
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membrane junction that creates protein channels linking cytosol of adjacent cells; allows ions and small molecules to flow between cytosols of the connected cells   Gap junctions  
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Double membrane surrounding cell nucleus   Nuclear envelope  
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opening in nuclear envelope through which molecular messengers pass between nucleus and cytoplasm   Nuclear pores  
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particular steroid (lipid) molecule which makes up 25% of cell membranes   Cholesterol  
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fine network of threads made up of DNA & nuclear proteins; principal component of chromosomes   Chromatin  
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highly coiled, condensed form of chromatin formed in cell nucleus during mitosis and meiosis forming rod like bodies   Chromosomes  
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densely staining nuclear region containing portions of DNA that code for ribosomal proteins   Nucleolus  
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cells which has no nucleus or organelles   Red blood cells  
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cells which have multiple nuclei   Skeletal muscle cells  
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protein factories of a cell; site of protein synthesis from amino acids, may be either free in cytosol or attached to endoplasmic reticulum   Ribosomes  
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cell organelle that consists of interconnected network of membrane-bound branch tubules & flattened sacs; 2 types, rough; with ribosomes attached to synthesize protein, smooth; (no ribosomes attached) synthesizes lipids & detoxifies certain molecules   Endoplasmic reticulum  
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cell organelle consisting of flattened membranous sacs; usually near nucleus; processes newly synthesized proteins for secretion or distribution to other organelles   Golgi apparatus  
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membrane bound vesicle produced by Golgi apparatus; contain protein to be secreted by cell   Secretory vesicle  
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cellular taxis that sorts & distributes vesicles   Endosomes  
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oval shaped body surrounded by "2" membranes; site of production of most ATP during cellular respiration   Mitochondria  
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cell organelle containing digestive enzymes in a highly acidic solution that break down bacteria, debris from dead cells, & or damaged cell organelles   Lysosomes  
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cell organelle that makes or disposes of hydrogen peroxide   Peroxisome  
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cytoplasmic filametous network which maintains the cell shape and provide cell movements; includes 3 types of protein filaments; microfilaments(actin), intermediate filaments, microtubules (cilia)   Cytoskeleton  
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hairlike extension on epithelial cells to propel material along epithelial surface   Cilia  
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unit of hereditary information; portion of DNA containing information req'd to determine a protein's amino acid sequence   Gene (20-25K genes in humans)  
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complete set of an organism's genes   Genome  
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Gene code is Universal, there are "3" Stop Codes, BUT only "1" Start Code   Universal genetic code for Methionine; A-U-G; "Start Code"  
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any change in base sequence of DNA that changes genetic information   Mutation (3 types)  
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the process of transferring genetic information from DNA to RNA in the nucleus   Transcription  
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the process that used the coded information in RNA to assemble a protein in the cytoplasm   Translation  
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ribonucleic acid that transfers genetic information for a protein's amino acid sequence from DNA to ribosome   Messenger RNA  
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enzyme that forms RNA by joining together appropriate nucleotides after they have base-paired to DNA   RNA polymerase  
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specific sequence of DNA nucleotide at the beginning of gene that controls the initiation of gene Transcription; determines which of the paired strands of DNA is transcribed into RNA template strand   Promoter  
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small intracellular peptide that attaches to proteins and directs them to proteasomes   Ubiquitin  
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a complex of proteins capable of denaturing (unfolding) other proteins and assisting in protein degradation   Proteasome  
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initial portion of newly synthesized protein (if protein is destined for secretion out of the cell)   Signal sequence  
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any molecule or ion that binds to protein surface by non covalent bonds (reversible)   Ligand  
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region of a protein to which a specific ligand binds   Binding site  
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selectivity; ability of binding site to react with only one, or limited # of molecules   Chemical Specificity  
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strength with which ligand binds to its binding site (can be high or low)   Affinity  
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refers to the fraction of total binding sites that are occupied by ligands at any given time   Saturation  
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ability of similar molecules to combine with the same binding site or receptor   Competition  
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alteration of a protein's shape, and therefore its function, by the covalent binding of various chemical groups to it   Covalent modulation (ex: Stereo's on/off switch)  
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addition of phosphate group to an organic molecule   Phosphorylation  
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any enzyme that phosphorylates other proteins by transferring to them a phosphate group from ATP   Protein kinase (ex: turns stereo on)  
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any enzyme that removes phosphate from protein   Phosphoprotein phosphatase (ex: turns stereo off)  
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control of protein binding site preoperties by modulator molecules that bind to regions of the protein other than the binding site altered by them   Allosteric modulation (ex: stereo's volume)  
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ligand that, by action at an allosteric regulatory site, alters properties of other binding sites on a protein and thus regulates its functional activity   Modulator molecule  
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site on protein that interacts with modulator molecule; alters functional site properties   Regulatory site  
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binding site on allosteric protein that when activated, carries out protein's physiological function; also called active site   Functional site  
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chemical reactions that occur in living organisms   Metabolism  
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the synthesis of organic molecules by cells   Anabolism  
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the breakdown of organic molecules by cells   Catabolism  
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chemical reaction in which energy release is small enough for reverse reaction to occur readily   Reversible reaction  
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chemical reaction that releases large quantities of energy and results in almost all reactant molecules being converted to product   Irreversible reaction  
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maxim that an increase in reactant concentration causes a chemical reaction to proceed in direction of product formation   Law of mass action  
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protein molecule, acts as protein catalyst that accelerates specific chemical reactions but does not itself undergo net chemical change during reaction   Enzyme (~2000 different enzymes in a typical cell)  
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substance that binds to a specific region of an enzyme & is necessary for the enzyme's activity   Cofactor  
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sequence of enzyme-mediated chemical reactions by which molecules are synthesized and broken down in cells   Metabolic pathway  
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metabolic pathway that breaks down glucose to 2 molecules of pyruvate(aerobically, with O2) or 2 molecules of lactate (anaerobically, lack of O2)   Glycolysis  
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mitochondrial metabolic pathway that utilizes fragments derived from carbs, proteins, and fat breakdown, & produces CO2, H, & small amounts of ATP   Krebs Cycle  
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