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Biotechnology - RCHS

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Answer
Human Genome Project   the project that found the order of all of the nucleotides in human DNA  
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PCR   DNA replication in a test tube  
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Gel Electrophoresis   the process of separating molecules on the basis of size and charge by passing them through a gel  
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Transgenic organism   an organism containing one or more genes from another species  
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Sticky ends   overhanging single strands of DNA left by some restriction enzymes  
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Genetic variation   this is reduced by inbreeding  
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Therapeutic cloning   cloning to create cells for medical purposes, usually stem cells  
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Nondisjunction   an error in cell division that creates cells with atypical numbers of chromosomes  
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Agarose   gelatin like substance used for separating DNA fragments by length and charge  
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Monosomy   having only one copy of a chromosome  
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Trisomy   having three copies of a chromosome  
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Inbreeding   mating between two closely related individuals  
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Pluripotent   able to become any cell in a living organism with the exception of extraembryonic structures such as the placenta  
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Genome   the set of chromosomes from one organism  
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Reproductive cloning   cloning to create a new living organism  
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Clone   an exact genetic replica of a gene, cell, or individual  
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DNA ligase   an enzymes that “glues” together fragments of DNA  
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Well   a hole in an agarose gel where a sample is placed  
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Restriction enzyme   an enzyme from bacteria that cuts DNA at a specific sequence  
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Recombinant DNA   cutting and pasting of DNA  
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Cell culture   growing living tissues outside of the organism; usually for research or therapeutic purposes  
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DNA fingerprinting   using DNA segments separated by electrophoresis to determine identity or familial relationships  
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Plasmid   a piece of circular DNA from bacteria; genes are inserted in these for cloning  
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Stem cells   cells that can divide to form many different cell types  
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Gene pool   all of the alleles in an interbreeding population  
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DNA polymerase   the enzyme used in PCR that elongates the DNA copy by adding nucleotides  
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Totipotent   able to become any cell in a living organism, including extraembryonic structures such as the placenta  
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Biotechnology   the use of living organisms to make, modify, or improve something  
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DNA sequence   the order of the nucleotides in the DNA of an organism  
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Karyotype   a physical arrangement of the chromosomes used for detecting genetic abnormalities  
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Dolly   the name of the first cloned mammal (a sheep)  
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Vector   any agent used to insert DNA into a cell; examples include plasmids, viruses, and gene guns  
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EcoR1   A restriction enzyme isolated from E. coli bacteria.  
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