PATH 375 Ch15
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| vulva | (blank)
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| labia majora | (blank)
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| labia minora | (blank)
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| clitoris | (blank)
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| urethral orifice | (blank)
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| vagina | (blank)
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| cervix | (blank)
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| uterus | (blank)
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| fallopian tubules | (blank)
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| ovaries | (blank)
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| Discuss the histology of female reproductive system 3x | (blank)
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| stratified squamous mucosa | (blank)
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| glandular epithelium | (blank)
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| germ cells | (blank)
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| ectocervix | touchable part
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| endocervix | canal part
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| endometrium | glandular epithelium
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| Hermaphroditism (1) defn (2) types | (blank)
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| True hermaphroditism | (blank)
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| male pseudohermaphroditism | inside male, outside female
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| female pseudohermaphroditism | inside female, outside male
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| How many female developmental abnormalities did we studied? | 1x Hermaphroditism
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| STD: female & male [chart] | (blank)
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| Is STD common? | yes
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| What are the usual symptoms of STD? | 1. vaginal discharge 2. leision 3. pelvic pain 4. dyspareunia
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| dyspareunia | painful intercourse
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| Female viral STD | 2x HSV HPV
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| HSV Type 2 (1) symptoms (2) on-set (3) rate (4) dormancy? (5) notes | (1) vesicles fuse together (coalesce) & ulcerate (2) 3-7 days (3) 30% infected = leisons (4) yes. neural ganglion cells (5) don't give birth when active
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| HPV (1) symptoms (2) types (3) | (1) labial, vaginal, cervical warts (condyloma) (2) those that will become carcinoma AND those that won't (HPV 6, 11) (3)
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| warts | (blank)
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| condyloma | (blank)
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| carcinoma | (blank)
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| condyloma acuminatum | large wart (HPV 6, 11)
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| Female bacterial STD | 1 chlamydia 2 gonorrhea 3 syphilis
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| Chlamydia (1) agent (2) symptoms | (2) urethritis / cervicitis / discharge / PID
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| Gonorrhea (1) agent (2) symptoms | (2) urethritis / cervicitis / discharge / PID
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| Syphilis (1) agent (2) symptoms | (2) vulvar ulcers
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| coalesce | fusion, vesicles
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| Bacterial vaginoses (1) types | general bacterial infection of vagina 3x
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| Candida | (blank)
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| Trichomonas | (blank)
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| Gardnerella | (blank)
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| Pelvic inflammatory disease (PID) (1) defn (2) cause (3) symptoms (4) complications 4x | Neisseria, Chlamydia (4) salpingitis, tubo-ovarian abscess, peritonitis
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| salpingitis | fallopian tubule
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| tubo-ovarian abscess | (blank)
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| peritonitis | (blank)
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| Complications of PID | (1) chronic non-specific (2) infertility if scar (3) pelvic mass (4) pain (5) spread of infection
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| Endometrial hyperplasia (1) defn (2) cause 2kinds (3) types | (blank)
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| hypothalamic - pituitary - ovarian axis | (blank)
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| estrogen VS progesterone | (blank)
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| anovulatory cycle | (blank)
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| functional cause | (blank)
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| organic cause | (blank)
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| Complex endometrial hyperplasia | (blank)
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| simple endometrial hyperplasia | (blank)
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| atypical endometrial hyperplasia | (blank)
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| typical endometrial hyperplasia | (blank)
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| endometrial adenocarcinoma | (blank)
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| What is one common thing about cancer in vulva, vagina & cervix? | they're all squamous cell carcinoma
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| Carcinoma of vulva (1) types 1x (2) progression / appearance (3) diagnosis (4) treatment | (1) squamous cell carcinoma (2) at first pre-cancer white/red patch, then ulcer or lump (3) biopsy (4) 1surgery 2+/- adjuvant therapy
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| white or red patch | (blank)
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| adjuvant therapy | (blank)
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| Carcinoma of vagina (1) types 2x | 1squamous cell carcinoma 2 clear cell carcinoma
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| squamous cell carcinoma: female reprod cancer... | vulva, vagina, cervix
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| clear cell carcinoma | DES (40-70s pill to prevent spontaneous abortion)
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| DES | 40-70s pill to prevent spontaneous abortion - vaginal clear cell carcinoma
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| Carcinoma of cervix (1) types 1x (2) risk factors 5x (3) location (4) progression / appearance (5) grading (6) prevention (7) virus (8) notes | (4) progression: dysplasia -> carcinoma in situ -> invasive (6) pap smear (7) HPV 16, 18, 31, 33, 34, 35 (8) koilocytic changes
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| Pap smear | (blank)
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| venereal disease | sexual contact disease
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| cervical dysplasia | (blank)
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| cervical intra-epithlial neoplasia | CIN
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| CIN | (blank)
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| CIS | carcinoma in situ
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| transition zone | between squamous epithelium & columnar epithelium (endo/exo-cervix)
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| koilocytic change | HPV
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| HPV histology is.. | koilocytic change
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| Neoplasms of the uterus (1) types | (blank)
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| Leiomyoma (1)defn b/m (2) treatment (3) risk group (4) symtpoms | (1) b smooth muscle cell uterus (2) estrogen (3) reproductive age (4) usually asympt, mass, bleeding..
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| fibroid | leiomyoma
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| most common uterine neoplasm is... | leiomyoma
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| Leiomyosarcoma (1) defn b/m (2) rate | (1) m smooth muscle uterus (2) rare
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| Endometrial adenocarcinoma (1) defn b/m (2) risk group (3) symptoms (4) risk factors 3x (5) stage/grade (6) diagnosis (7) treatment | (1)m epith cell endometrium (2) elderly f (3) vaginal bleed (4) 1tumor that secretes estrogen 2taking exogenous estrogen 3obesity 4nulliparous 5early menarche 6late menopause (5)I-IV/LMH (6)biopsy / dilation & curettage (7) hysterectomy +adjuvant treatmen
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| hyperestrinism | too much estrogen
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| what is the most common malignant tumor of female reproductive tract? | endometrium adenocarcinoma
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| estrogen secreting tumor | endometrium adenocarcinoma
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| take exogenous estrogen | endometrium adenocarcinoma
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| obestity is a risk factor for... | endometrium adenocarcinoma
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| nulliparous | (blank)
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| menarche | (blank)
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| menopause | (blank)
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| dilation and curettage | (blank)
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| hysterectomy | (blank)
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| adjuvant therapy | endometrium adenocarcinoma
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| ovarian cyst (1) defn (2) causes 3x (3) symptoms (4) big/small cyst? poly?single? | easily confused with cancer (1) follicules filled with fluid (2) 1follicles -> cyst 2cystic corpora lutea 3inclusion of surface cells (3) asymptomatic (4) small, single -- easily confused with cancer
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| unruptured follicles | ovarian cyst
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| follicular cysts | ovarian cyst
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| cystic corpora lutea | ovarian cyst
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| inclusion of ovary surface cells | ovarian cyst
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| Polycystic ovary syndrome (1) defn (2) symptoms (3) consequence | (1) hormone bad (2) no M (3) infertility
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| adrenal | kidney
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| Ovarian neoplasm (1) rate (2) types 3x (3) risk factors | (1) most death f ; 2nd common f reprof (2) surface, germ, stromal (3) ovarian dysgenesis, mutation BRCA1 BRCA2
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| What cancer is the second most common group in female reprod tract? | ovarian
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| What cancer has highest mortality of female reproductive tract? | ovarian
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| Is ovarian cancer common in young female? | No
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| ovarian dysgenesis | (blank)
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| BRCA1 & BRCA2 | (blank)
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| Is oral contraceptives linked to ovarian cancers? | No
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| Surface epithelial tumors @ cervix (1) rate amg cervix cancer (2) types 5x | (1) highest 70% (2) serous, mucinous, endometrioid, clear cell, transitional cell
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| Which is the most common ovarian cancer? Surface?Germ?Stromal? | surface, 70%
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| serous epithelial tumor (1) secretion? (2) appearance (3) grading | (blank)
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| mucinous epithelial tumor (1) secretion? (2) appearance (3) grading | (blank)
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| endometriod epithelial tumor (1) secretion? (2) appearance (3) grading | (blank)
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| Germ cell tumor @ cervix (1) rate (2) risk group | (1) 20% (2) young f
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| what tumor will contain fat, hair and teeth/bone? | ovarian teratoma
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| Teratoma (female) | (blank)
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| Immature teratoma (female) | (blank)
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| sebaceous material | (blank)
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| dermoid cysts | (blank)
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| tumor of germ cells developed into neural tissues | (blank)
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| Fibroma | (blank)
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| fibroblast | (blank)
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| Thecoma | (blank)
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| Theca cells | spindle cells - produce estrogen
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| spindle cells | Theca cells - produce estrogen
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| Granulosa cell tumor | granulosa cell
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| Granulosa cell | produce estrogen
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| 4 Causes of infertility | (blank)
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| Asherman's syndrome | (blank)
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| ectopic pregnancy | rupture
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| trophoblast cells | epith lining of placental villi
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| placenta accreta | (blank)
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| placental villi | (blank)
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| placenta previa | (blank)
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| toxemia | (blank)
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| preeclampsia | (blank)
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| eclampsia | (blank)
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| Gestational trophoblastic disease (GTD) | (blank)
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| Hydatidiform mole (1) cause (2) consequence | chorionic villi - no fetal movement, high hCG
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| hydropic degeneration | (blank)
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| chorionic villi disease | (blank)
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| complete mole | no fetus / 46xx, all pateranl
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| incomplete mole | little fetus / 69 fmm
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| Choriocarcinoma | highly malignant, treat with methotrexate
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| methotrexate | Choriocarcinoma
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| What is abortion? | <500 g , 20wks
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| Rate of Spontaneous abortions | 1/3 of all preg
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| complete abortion | (blank)
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| incomplete abortion | (blank)
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| missed abortion | (blank)
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| threatened abortion | some live, some die
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| Endometriosis | (blank)
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| chocolate cyst | (blank)
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