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operative surgery

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Question
Answer
Surgical objectives   preserve or restore function restore structure (anatomic reconstruction) preserve or restore appearance minimize morbidity  
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what % of uncomplicated surgeries result in infection?   2-5%  
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Halstead's surgical principles   Gentle tissue handling Aseptic technique Hemostasis Anatomic reconstruction Minimize dead space Minimize foreign material Manage concurrent disease  
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key events of surgical injury and healing   hemostasis inflammation proliferation remodeling scar maturation  
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Reasons for dehiscence   loss of tissue integrity loss of suture integrity excessive forces on wound  
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surgical factors contributing to wound complications   excessive tissue inflammation infection necrosis excessive forces  
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suture pullout   the force required to pull a suture out of a tissue (= relative holding strength of the tissue)  
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relative tissue strengths   fascia(3.77Kg) > skin(1.82Kg) > muscle(1.27Kg) > fat(0.2Kg)  
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describe the ideal suture   loses tensile strength at the same rate as the tissue of a healing wound gains tensile strength  
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what are desirable characteristics of a suture   biocompatibility ease of handling knot security non-capillary absorption inhibition of microbial growth  
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absorbable, short lasting, natural suture   Catgut TS = 7-14d Abs = 40-60d  
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absorbable, short lasting, synthetic suture   vicryl rapide TS = 7-14d Abs = 40-60d  
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absorbable, medium lasting, braided suture   Vicryl Braided Dexon TS = 14-28 Abs = 60-90+d  
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Absorbable, medium lasting, monofilament suture   Monocryl Dexon TS = 14-28d Abs = 60-90+d  
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absorbable, long lasting, monofilament suture   Maxon PDSII Biosyn TS >40d Abs = 120-180+d  
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Tensile strength retention vicryl rapide   50% in 5-6d 0% in 2wks  
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Tensile strength retention Monocryl   60-70% in 1wk 30-40% in 2wks  
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Tensile strength retention coated vicryl   50% in 3wks  
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Tensile strength retention PDSII   50% in 4wks  
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zone of inflammation   ~4mm from incision want sutures beyond this to avoid inflammatory degradation of suture material  
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vicryl rapide TSRP Abs   TSRP = 50% 5-6d Abs = 42d  
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monocryl TSRP Abs   TSRP = 60-70% 1wk; 30-40% 2wks Abs = 90-119d  
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coated vicryl TSRP Abs   TSRP = 50% 3wks Abs = 56-70d  
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PDSII TSRP Abs   TSRP = 50% 4wks Abs = 180-210d  
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What are the most commonly used sized suture needles in veterinary medicine?   3/8 circle and 1/2 circle  
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name three grips for holding needle drivers   thumb finger - more control thenar - more flexibility palmed - more force applied to needle  
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Different approaches to hemostasis   pressure clamping ligation sealing hemostatic agents  
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Double ligation of vessels   2 ligatures placed 2-4mm apart may need more than 2 (and placed farther apart) for large vessels  
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Why do you want to minimize dead space?   reduces space for collection of serum serum is a nidus for infection and also puts gravitational tension on suture line  
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What are some techniques for minimizing dead space   apposition of tissue layers (+/- tacking) external pressure bandage drains (active/passive) loose wound packing (with gradual removal)  
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"Clean Wound"   non-tramatic no break in technique no inflammation no GI, genitourinary, respiratory  
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"Clean Contaminated Wound"   minor break in technique GI, genitourinary, but no significant spillage  
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"Contaminated Wound"   Major technique break GI, genitourinary with spillage freshly traumatic wound  
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"Dirty Wound"   acute bacterial inflammation transection clean tissue to access pus traumatic wound, devitalized tissue, foreign body, fecal contamination, delayed treatment  
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How do you calculate risk of surgical site infection?   (Dose of bacterial contamination X virulence of bacteria) divided by resistance of host  
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critical bacterial inoculum   10^5 microorganisms/gram tissue  
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antimicrobial prophylaxis   procedures > 2hr procedures with implants dental GI Open Fx repair Orthopedics perineal hernia repair  
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when should antimicrobial prophylaxis be given?   <2hr before incision  
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what is the best way to minimize surgical site infection   excellent surgical technique -asepsis -gentle tissue handling -hemostasis -accurate apposition  
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anesthetic drug groups   Parasympatholytics (atropine) Neuroleptanalgesics (acepromazine/ hydromorphone; acepromazine/oxymorphone) Opioids (Morphine)  
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atropine   rapid onset short duration blocks muscarinic effects on heart and glands  
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acepromazine   long onset long duration sedation, antiarrhythmic, cheap hypotension, seizures, no analgesia  
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hydro- and oxymorphone   short onset 4-6hr duration good analgesia (+/- sedation) panting, bradycardia, regurgitation, excitability  
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acepromazine/oxymorphone (or hydro)   good sedation and analgesia lower doses less vomiting panting bradycardia regurgitation  
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morphine   long onset long duration excellent sedation and analgesia vomiting, panting, bradycardia, hypothermia, vasodilation, histamine release  
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what's an advantage of normosol R and plasmalyte?   they don't have Ca  
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When do you give horses prolylactic abx?   Commonly b/c fear risk of respiratory dz After Kelby's mom induces penile abrasions  
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Which abx do you commonly give to dogs in sx? For which bacteria?   Cefazolin - effective against 99% Staph & 90% Ecoli (coagulase + Staph and Ecoli)  
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Which abx do you commonly give to horses in sx? For which bacteria?   Penicillin + aminoglycoside (Gentamicin/amikacin) for Staph & Strep & Enterobacteriacea  
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What are the 4 general recommendations for abx prophylaxis?   -give immediately before incision (<2h) -redose if lengthy procedure -no additional benefit after 24h -if a drain is placed, continue abx for 24h post drain removal -if Kelby's mom has open sores  
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4 reasons we premedicate   -sedation (gettin' her "in the mood") -preemptive analgesia (before tight backdoor penetrations) -decrease injectable/inhalant (you only have so much in your date-rape kit) -block side effects associated with drugs/procedure (screaming and fighting bac  
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What kind of closure should you use on Kelby's mom's gaping anus?   Trick Question: Let the 5 guys after you worry about the closure  
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