ANA and other ABs
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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Anti-ds-DNA (native DNA) | SLE only (60%); an indicatore of disease activity and lupus nephritis
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Anti histone | Drug induced lupus (95%)
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Anti centromer | CREST
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Anti-SM | SLE only (25-30%)
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Anti Ro (SSA) | Sjogren; neonatal lupus
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Anti LA (SSB) | Sjogren
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Anti RNP | Mixed Connective Tissue Disease 100%
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Anti glomerular basement membrane antibody | Goodpasture
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Scl-70 (anti-DNA topoisomerase 1): | progressive systemic sclerosis; anti-centromere more in the localized form (CREST)
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c-ANCA | Wegener
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p-ANCA | PAN and Churg Strauss syndrome and Primary Sclerosing Cholangitis; Ulcerative colitis (50-80%)
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Anti-Jo1 | inflammatory myopathies
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Anti Smith antibodies | SLE specific
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HLA-B27 | Ankylosing spondylitis; also reactive and psoriatic arthritis
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DR4 and DR1 | Rheumatoid arthritis
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DR3 | Sjogren, SLE and also RA
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Created by:
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