Psychotherapuetic agents
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| chlorpomazine (Thorazine) | (blank)
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| haloperidol (Haldol) | (blank)
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| chlorpomazine (Thorazine) | antipsychotic older med- blocks dopamine
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| haloperidol (Haldol) | antipsychotic--- older med -- blocks dopamine
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| clozapine (Clozaril) | antipsychotic -- works on serotinon and dopamine
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| resperidone (Risperdal) | antipsychotic -- works on serotinon and dopamine
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| olanzapine (Zyprexa) | antipsychotic -- works on serotinon and dopamine
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| ziprasidone (Geodon) | antipsychotic -- works on serotinon and dopamine
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| arirpiprazole (Abilify) | antipsychotic -- works on serotinon and dopamine
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| older antipsycholitcs SE | momement disorders known as EPS (Extrapyrmaidal side effects)
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| SE of antipsychotics-- | photsensity, sedation and orthostatic hypotension, anticholinergec effects, rare, dangerous SE-- nerulopetic malginant syndrome
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| clozapine (Clozaril) SE | agranulocytosis --An acute disease marked by high fever and a sharp drop in circulating granular white blood cells.
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| SSRI | Inhibition of serotinon reuptake - also weak effects of norepiniphine and dopamin uptake . 2nd and 3rd generation less selective and have activity on brain seratonin as well as norepinephrine receptors
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| older antiphsychotic work best on.... | work best on "positive" symptoms such as hallucinations, delustions
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| newer antiphsychotics work best on.... | work on "negative or deficit" sx such as apathy, social withdrawal
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| fluoxetine (Prozac) | SSRI antidepressent
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| Sertaline (Zoloft) | SSRI antidepressent
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| paroxetine (Paxil) | SSRI antidpressent
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| citalopram (Celexa) | SSRI antidpressent
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| escitaloporam oxalate (Lexapro) | SSRI antidpressent
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| TCAs (tricyclics) | inhibit the uptake of seratonine and norepinephrine at nerve endings =these nuerotransmitters accumulate at nerve ending
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| aminotriptyline (Elavil) | TCAs
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| MAOI | inhibits the breaking down of neurotransmitters which alleviates symptoms of depression = Any of a class of antidepressant drugs that block the action of monoamine oxidase in the brain, thereby allowing the accumulation of monoamines such as norepinephri
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| MAOI SE | tryamine can cause adverse food allergies
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| phenelizine (nardil) | MAOI
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| buporopion (Wellbutrin or Zyban) | 2nd gen. of modles effect on blockagedof dopamine -- smoking cessation
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| vemlafaxine (Effexor) | meds that regulate serotonin and norepinephrine
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| duloxetine (Cymbalta) | regualte serotonin and norepinephrine
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| Antipressants major uses (SSRI, MAOI, & other ) | majordepression, obsessive compulsive disorder (OCD), panic disorders (MAOIs sometimes used), PMS, chemical dpedency with depression (dual dx), seasonal affective disorder
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| Prozac admin info | give in am and po
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| SSRI SE | insominia, wt gain, and sexual dysfunction
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| TCA SE | tendency to cause fatal cardiac dysrhythmias following overdose.
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| Newer generation antidepressant SE | headache, dizziness, tremor, nervousness, insomnica, fatigue, nausea, diarrhea, constipation,dry mouth, weithgt loss/gain, sweating, sexu dysfunction
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| bupropion side effects | associated with reduced sexua side effects.
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| antidepressent combination SE | serotonin sydrome (serotonigergic activity)
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| TCA's contraindication | should not be used within 2 wks of MAOIs (hypotension and tachycardia)
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| SSRI contraindication | should not be used within 2-5 wks of MAOIs (serotinin syndrom could be fatoal withhyperthermia, rigitidy, fluctuation VS, delirium, coma)
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| MOAIs contraindication | hypertensive crisisif not on low tyramine diet
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| lithium carbonate (lithodbid) | mood stabilizer
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| carbamazepine (Tegretol) | mood stabilizer
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| vlaproic acid (Depakote) | mood stabilizer
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| gabapentin (Neurontin) | mood stablizer
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| lithium carbonate (lithobid ) MOA | exact MOA unknown it is anutrally occuring salt - alters neuronal socium transport
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| carbamenazepine (Tegretol) MOA | reduces post -tetanic potentiation, decreasing seizure to spread; similiar to TCAs
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| lithium carbonate (lithobid) indicated for | treatment of choice of mania; prevent recurrent suicidal depression
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| lithium routes | PO
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| lithium ranges | .8-1.2 or aoun 1.0
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| lithium side effects | Lethargy, slurred speech, muscle weakness, fine hand tremor
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| lithium toxicity | levels above 1.5 or 2.0possible causes of toxicity - lfuid and salt intake important
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| chlordiazapoxide (Librium) class | antianziety meds - benzodiazepine
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| Lorazepam (Ativan ) class | antianziety meds - benzodiazepine
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| chlordiazapoxide (Librium) MOA | potentiate GABA
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| Lorazepam (Ativan ) MOA | potentiate GABA
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