NUR 370 Unit 2 Prototype Drugs
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| sulfamethoxazole-trimethoprim, sulfisoxazole-erythromycin | Sulfonamide prototypes
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| penicillin V potassium, penicillin G potassium, amoxicillin | Penicillin prototypes
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| cefazolin, cephalexin, keflex, cefoxitin, cefuroxime, ceftriaxone, cefepime | Cephalosporin prototypes
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| imipenm-cilastatin | Carbapenem prototypes
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| aztreonam | Monobactam prototypes
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| doxycycline, aoxycycline | Tetracycline prototypes
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| erythromycin, azithromycin, clarithromycin | Macrolide prototypes
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| gentamicin | Aminoglycoside prototypes
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| ciprofloxacin | Fluoroquinolone prototypes
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| telithromycin | Ketolide prototypes
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| clindamycin, vancomycin | Miscellaneous antibiotic prototypes
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| acyclovir, ganciclovir | Antiviral prototypes
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| zidovudine, nevirapine, indinavir | Antiretroviral prototypes
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| isoniazid | Antitubercular prototypes
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| amphotericin B, fluconazole | Antifungal prototypes
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| chloroquine, hydroxychloroquine, primaquine | Antimalarial prototypes
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| metronidazole | Antiprotozoal prototypes
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| mebendazole | Antihelmintic prototypes
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| Trimethoprim/sulfamethoxazole trade name | co-trimoxazole, Bactrim, Septra
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| Erythromycin/sulfisoxazole trade name | Pediazole
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| Amoxicillin trade name | Amoxil, Trimox, Wymox
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| Cefazolin trade name | Kefzol, Ancef
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| Keflex trade name | Cephalexin
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| Cefoxitin trade name | Mefoxin
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| Cefuroxime trade name | Kefurox, Ceftin
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| Ceftriaxone trade name | Rocephin
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| Cefepime trade name | Maxipime
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| Gentamicin trade name | Garamycin
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| Ciprofloxacin trade name | Cipro
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| Imipenm-cilastatin trade name | Primaxin
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| Erythromycin trade name | E-mycin
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| Azithromycin trade name | Zithromax
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| Clarithromycin trade name | Biaxin
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| Aztreonam trade name | Azactam
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| Doxycycline trade name | Vibramycin, Monodox
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| Telithromycin trade name | Ketek
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| Clindamycin trade name | Cleocin
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| Vancomycin trade name | Vancocin, Vancoled
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| Acyclovir trade name | Zovirax
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| Ganciclovir trade name | Cytovene
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| Zidovudine trade name | Retrovir, AZT
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| Nevirapine trade name | Viramune
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| Indinavir trade name | Crixivan
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| Isoniazid trade name | INH
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| Amphotericin B trade name | Amphocin, Fungizone
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| Fluconazole trade name | Diflucan
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| Chloroquine trade name | Aralen
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| Hydroxychloroquine trade name | Plaquenil
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| Metronidazole trade name | Flagyl
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| Mebendazole trade name | Vermox
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| Fentanyl citrate trade name | Duragesic
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| Meperidine HCl trade name | Demerol
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| Methadone HCl trade name | Dolophine
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| Oxycodone trade name | Oxycontin
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| Hydrocodone trade name | Hycodan
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| Naloxone HCl trade name | Narcan
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| Aspirin trade name | acetylsalicylic acid
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| Acetaminophen trade name | Tylenol
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| Indomethacin trade name | Indocin
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| Ibuprofen trade name | Motrin, Advil
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| Ketorolac trade name | Toradol
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| Celecoxib trade name | Celebrex
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| Azathioprine trade name | Imuran
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| Allopurinol trade name | Zyloprim
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| Sumatriptan trade name | Imitrex
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| Sulfonamides: half-life, onset, peak, duration | half-life= 7-12 hr, onset= variable, peak= 2-4 hr (plasma), duration= up to 12 hr
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| Beta-Lactam antibiotics | penicillins, caphalosporins, carbapenems, monobactams
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| Natural penicillins: half-life, onset, peak, duration | half-life= 30 min, onset= variable, peak= 30-60 min, duration= 4-6 hr
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| Aminopenicillins: half-life, onset, peak, duration | half-life= 1-1.3 hr, onset= 0.5-1 hr, peak= 1-2 hr, duration= 6-8 hr
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| Cefazolin: half-life, onset, peak, duration | half-life= 1.2-2.2 hr, onset= variable, peak= 1-2 hr, duration= variable
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| Keflex: half-life, onset, peak, duration | half-life= .05-1.2 hr, onset= variable, peak= 1 hr, duration= 6-12 hr
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| Cefoxitin: half-life, onset, peak, duration | half-life= 30-60 min, onset= variable, peak= 20-30 min, duration= variable
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| Ceftriaxone: half-life, onset, peak, duration | half-life= 4.3-8.7 hr, onset= variable, peak= 2-4 hr, duration= 24 hr
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| Cefepime: half-life, onset, peak, duration | half-life= 2 hr, onset= 0.5 hr, peak= 0.5-1.5 hr, duration= 8-12 hr
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| Imipenem-cilastatin: half-life, onset, peak, duration | half-life= 2-3 hr, onset= variable, peak= 2 hr, duration= 6-8 hr
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| Aztreonam: half-life, onset, peak, duration | half-life= 1.5-2 hr, onset= variable, peak= 1 hr, duration= 6-12 hr
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| Azithromycin: half-life, onset, peak, duration | half-life= 6-8 hr, onset= variable, peak= 2.5 hr, duration= up to 24 hr
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| Clarithromycin: half-life, onset, peak, duration | half-life= 3-7 hr, onset= variable, peak= 2 hr, duration= up to 12 hr
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| Telithromycin: half-life, onset, peak, duration | half-life= 9-10 hr, onset= unknown, peak= 1 hr, duration= unknown
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| Doxycycline: half-life, onset, peak, duration | half-life= 12-24 hr, onset= variable, peak= 1.5-4 hr, duration= up to 12 hr
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| Gentamycin: half-life, onset, peak, duration | half-life= IV 2 hr, onset= vaiable, peak= IV 0.5-2 hr, duration= IV 8-12 hr
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| Ciprofloxin: half-life, onset, peak, duration | half-life= 3-4.8 hr, onset= variable, peak= 1-2.3 hr, duration= up to 12 hr
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| Clindamycin: half-life, onset, peak, duration | half-life= 2.4 hr, onset= variable, peak= 45 min, duration= up to 6 hr
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| Metronidazole: half-life, onset, peak, duration | half-life= 8 hr, onset= unknown, peak= 1-2 hr, duration= unknown
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| Ganciclovir: half-life, onset, peak, duration | half-life= 4-8 hr, onset= unknown, peak= 24 hr, duration= variable
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| Zidovudine: half-life, onset, peak, duration | half-life= 0.78-1.93 hr, onset= unknown, peak= 0.4-1.5 hr, duration= 3-5 hr
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| Nevirapine: half-life, onset, peak, duration | half-life= 25-30 hr, onset= 2 hr, peak= 2-4 hr, duration= 24 hr
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| Indinavir: half-life, onset, peak, duration | half-life= 1.5-2.5 hr, onset= 2 weeks, peak= 0.5-1 hr, duration= 6 months
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| Chloroquine: half-life, onset, peak, duration | half-life= 8-10 days, onset= 8-10 hr, peak= 2 hr, duration= variable
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| Hydroxychloroquine: half-life, onset, peak, duration | half-life= 32-50 days, onset= several hrs, peak= few hr, duration= variable
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| Primaquine: half-life, onset, peak, duration | half-life= >4-6 hr, onset= <2 hr, peak= 1-3 hr, duration= 24 hr
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