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RBC forms/anemia

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Question
Answer
Spherocytes   Hereditary spherocytosis, autoimmune hemolysis  
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Elliptocyte   hereditary elliptocytosis  
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Macro-ovalocyte   Marrow failure, Megablastic anemia (hypersegmented polys common),  
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Helmet cell/schistocyte   DIC, TTP/HUS, traumatic hemolysis  
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Sickle cell   Sickle cell anemia  
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Acanthyocyte (spur cell)   Spiny appearance in liver disease and abetalipoproteinemia  
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Target cell   HbC disease, Asplenia, Liver disease, Thalassemia  
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Burr cell   TTP/HUS  
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Basophilic stippling   Thalassemia, Anemia of chronic disease, Iron deficiency, lead poisoning  
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HALT   Pneumonic for taret cells (Hbc disease, asplenia, liver disease, thalassemia)  
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Tail   Basophilic stippling (Thalassemia, anemia of chronic disease, iron deficiency, lead poisoning)  
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Heinz bodies formation   Oxidation of iron from ferrous to ferric form leads to denature hemoglboin preciptiation and damage to RBC membrane (bite cells)  
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Howell Jolly bodies formation   Basophilic nuclear remnants found in RBC  
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Howel jolly bodies   Hyposplenia, asplenia  
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Heinz bodies   alpha thalassemia, G6PD deficiency  
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Microcytic anemias   Iron deficiency, Thalassemia, Lead poisoning, sideroblastic anemia  
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Macrocytic   Megaloblastic (B12/folate), drugs that block DNA (sulfa, phenytoidn AZT)  
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Normocytic   hemorrhage, enzyme defects, RBC defects (hereditary), bone marrow disorders, hemaglobinopathies (sickel cell), auotimmune hemolytic, Anemia of chronic disease  
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Iron deficiency = serum iron, TIBC, ferritin levels   decreased serum iron, increased TIBC, decreased ferritin  
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Anemia of chronic disease= TIBC, ferritin   Decreased TIBC, increased ferritin,  
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Pneumonic for microcytic anemia   LIST (lead poisoning, iron deficiency, sideroblastic anemia, thalassemia)  
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