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Prochlorperazine

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Question
Answer
Prochlorperazine GENERIC NAME   Prochlorperazine  
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Prochlorperazine BRAND NAME   Compazine  
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Prochlorperazine CLASS   Antiemetics, antipsychotics  
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Prochlorperazine MECHANISM OF ACTION   Alters the affects of dopamine in the CNS. Possesses significant anticholinergic and alpha-adrenergic blocking activity. Diminished N/V and diminished signs and symptoms of psychoses and anxiety  
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Prochlorperazine INDICATIONS   N/V, psychoses, and anxiety.  
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Prochlorperazine CONTRAINDICATIONS   Narrow-angle glaucoma, severe liver or cardiovascular disease, bone marrow depression, children < 2 years.  
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Prochlorperazine ADVERSE REACTIONS   extrapyramidal reactions, sedation,blurred vision, dry eyes, ECG changes, hypotension, tachycardia  
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Prochlorperazine INCOMPATABILITIES/DRUG INTERACTIONS   Additive hypotension with antihypertensives, nitrates, or acute ingestion of alcohol. Additive CNS depression with other CNS depressants.  
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Prochlorperazine DOSE/ROUTE Adult Antiemetic PO   5-10mg 3-4 times daily. Up to 40 mg/daily  
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Prochlorperazine DOSE/ROUTE Adult Antiemetic IV   2.5-10mg not to exceed 40mg/daily.  
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Prochlorperazine DOSE/ROUTE Adult Antipsychotic PO   5-10mg 3-4 times daily not to exceed 150mg a day  
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Prochlorperazine DOSE/ROUTE Adult Antipsychotic IV   2.5-10mg not to exceed 40mg day  
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Prochlorperazine DOSE/ROUTE Adult Antianxiety PO   5mg 3-4 times daily not to exceed 40mg/daily  
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Prochlorperazine DOSE/ROUTE Adult Antianxiety IV   2.5-10mg not to exceed 40 mg/daily  
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Prochlorperazine ONSET OF ACTION   PO 30-40minutes.IV rapid  
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Prochlorperazine PEAK EFFECTS   Unknown  
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Prochlorperazine DURATION OF ACTION   3-4 hours  
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Prochlorperazine AZ DRUG BOX SUPPLY RANGE   Not carried  
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Created by: klindley
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