Nicotine/Smoking for Biology of Drugs
Help!
|
|
||||
|---|---|---|---|---|---|
| In which part of the tobacco plant is nicotine found? | The Leaves
🗑
|
||||
| 1-Methyl-2-(3-pyridyl) pyrrolidine | the chemical name for nicotine
🗑
|
||||
| Is there a fatal dose of nicotine? | Yes
🗑
|
||||
| T or F: nicotine is a commonly used insecticide | True
🗑
|
||||
| _________ forms of nicotine can be absorbed across mucosal surfaces. E.g., snuff through the oral mucosa. | Alkaline
🗑
|
||||
| To be absorbed in the lungs via smoke inhalation, nicotine must be converted from an _________ form to an ______ form and dissolved in ___. | ALKALINE to ACIDIC and dissolved in TAR.
🗑
|
||||
| Faster absorption: inhalation or oral? | inhalation
🗑
|
||||
| How quickly does inhaled nicotine arrive to the brain? | Within 10 seconds
🗑
|
||||
| Where is nicotine metabolized? | Liver
🗑
|
||||
| Nicotine half-life | 2 hours
🗑
|
||||
| Cotinine | the major nicotine metabolite
🗑
|
||||
| Cotinine half-life | 24 hours
🗑
|
||||
| T or F: nicotine increases dopamine levels in the nucleus accumbens | True
🗑
|
||||
| Nictotine is considered addicting because it increases ________ in the _______ _________. | dopamine, nucleus accumbens
🗑
|
||||
| The nucleus accumbens is known as the brain’s _______ center | reward
🗑
|
||||
| Ciliary Escalator | the body’s mechanism to trap inhaled particles and push it out of the respiratory tract, using cilia and mucous
🗑
|
||||
| 2 ways nicotine/smoking affect the ciliary escalator? | 1. paralyzes the cilia lining the respiratory tract and 2. stimulates excessive mucous production
🗑
|
||||
| How long after stopping smoking does it take for cilia to return to normal functioning? | Up to 9 months
🗑
|
||||
| What is the significance of non-functioning cilia? | Unable to clear lungs
🗑
|
||||
| EMPHYSEMA is to POOR GAS EXCHANGE, as ______ __________ is to POOR AIR MOVEMENT | CHRONIC BRONCHITIS
🗑
|
||||
| Emphysema involves destruction of which lung structures and the inability to completely do what? | alveoli (air sacs); exhale
🗑
|
||||
| Chronic Bronchitis is inflammation of what? | The bronchioles
🗑
|
||||
| Bronchioles | The large tubes that transport air to the alveoli
🗑
|
||||
| COPD is a combo of which 2 respiratory diseases? | emphysema and bronchitis
🗑
|
||||
| Inhaled carbon monoxide (CO) binds ____________ to hemoglobin, taking up needed space to carry ______ (__) to the tissues, decreasing the body’s O2 supply. | irreversibly; oxygen; O2
🗑
|
||||
| T or F: smoking can be attributed to 95% of all lung cancers | True
🗑
|
||||
| T or F: Tobacco smoke contains over 40 known carcinogens | True
🗑
|
||||
| T or F: persons with psychiatric disorders who smoke tend to have more difficulty quitting | True
🗑
|
||||
| How does smoking during pregnancy affect the fetus’s blood supply? | Lowers it
🗑
|
||||
| T or F: smoking during pregnancy is associated with low birth weight, premature births, birth defects, SIDS, allergies, leukemia, and ear infections | True
🗑
|
||||
| What is the relationship between SIDS and smoking | SIDS is more common in smoker households
🗑
|
||||
| Schizophrenic symptoms tend to get _____ when schizophrenics try to quit smoking | worse
🗑
|
||||
| Smokers at risk for depression are ____ likely to become depressed after they stop smoking. | more
🗑
|
||||
| 3 components of Environmental Tobacco Smoke | Mainstream, Sidestream, Exhaled
🗑
|
||||
| Mainstream smoke | the smoke inhaled through the filtered end of a cigarette
🗑
|
||||
| Sidestream smoke | the smoke from the lit end of a cigarette
🗑
|
||||
| Exhaled smoke | the smoke exhaled by the smoker
🗑
|
||||
| More carcinogens: Sidesteam or Mainstream smoke? | Sidestream. It is unfiltered.
🗑
|
||||
| Name some ways smoking contributes to the risk of heart attacks | increases blood clots, causes cardiac arrhythmias, decreases HDL & increases LDL
🗑
|
||||
| Zyban, a smoking deterrent is the same drug as which antidepressant? | Wellbutrin
🗑
|
||||
| Early signs of nicotine toxicity | sweating, nausea, tremors
🗑
|
||||
| Late signs of nicotine overdose | seizures, cardiac arrest, respiratory failure
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
jondoh
Popular Pharmacology sets