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UA/Micro Chapter 8

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Term
Definition
BUN   blood, urea, nitrogen  
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CDC   Centers for Disease Control  
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OSHA   Occupational Safety & Health Administration  
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epidemology   study of infectious disease  
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normal flora   helpful and necessary for life processes  
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pathogens or infectious agents   microorganisms that cause disease  
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stages of infection cycle   infectious agent, reservoir/source, portal of exit, means of transmission, portal of entry, susceptible host  
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infectious agents   bacteria, viruses, parasites (Rickettsia), protozoa, fungus (mold & yeast)  
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examples of reservoir   almost anything - vectors, water, food, fomites, humans  
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means of transmission   direct & indirect contact, vertical transmission, airborne, droplet, iatrogenic, inhalation  
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iatrogenic transmission   due to medical treatments, procedures, surgeries, injections  
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portal of entry/portal of exit   inhaled, ingested, absorbed - respiratory, gastrointestinal, urinary, reproductive tracts  
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anaerobes   microorganisms that grow without O2  
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environmental requirements for microorganisms   nutrients, O2 or no O2, temperature, PH, darkness, moisture,  
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stages of infection   invasion/multiplication, incubation, prodromal, acute, declining, convalescent  
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invasion stage   pathogenic microorganism enters body and begins to multiply, no signs or symptoms  
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incubation   first sign or symptoms  
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prodromal   definitive signs or symptoms i.e. fever, rash  
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acute   infection at its peak  
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declining   symptoms subside  
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convalescent   return to original state of health  
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inflammatory response   body's natural reaction to infection - to heal and replace injured tissue  
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cell-mediated immunity   T-cells activated - directly attack cancer cells, viruses, etc. (phagocytes) (thymus)  
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humoral immunity   B-cell lymphocytes produce antibodies that lock into antigen and neutralize (bone marrow)  
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immunity   body's ability to defend itself against pathogens and toxins  
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natural immunity   occurs as a result of being exposed to a pathogen  
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natural active immunity   direct exposure to antigen - body builds it's own protection  
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natural passive immunity   antibodies passed from mother to fetus  
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artificial immunity   occurs as a result of being given either antigen or antibodies  
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artificial passive immunity   pt is injected with antibodies (immunoglobulins)  
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artificial active immunity   pt given small amounts of antigen (immunization) to stimulate antibody reaction  
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live attenuated vaccine   weakened form of pathogen - produce antibodies against pathogen (MMR)  
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asepsis   free of germs  
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medical asepsis   destruction of microorganisms after leaving the body  
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surgical asepsis   destruction of microorganisms before they enter the body (sterilization for surgery)  
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hypochlorite solution   bleach (10%)  
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hepatitis   inflammation of the liver  
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Exposure Control Plan   developed by employer to protect employees that are at risk for exposure for BBP or OPIM  
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OPIM   other potentially infected materials  
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BBP   blood borne pathogens  
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regulated waste   infectious waste - medical waste contaminated with blood, body fluids, OPIM  
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work practice controls   methods used in workplace to protect employees from exposure  
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resident flora   normal flora present on skin  
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transient flora   bacteria on hands picked up via contaminated objects  
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nosocomial   disease originating in hospital - flora not found on hands  
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sanitization   cleaning process to remove tissue, blood or body fluids  
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disinfection   destroying microorganisms on fomites using chemicals (except for spores)  
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sterilization   complete destruction of all microorganisms - usually by autoclave  
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antigen   invading organism (bacteria or virus) that stimulates antibody production  
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antibodies   produced by B-cells (B-lymphocytes) attach to specific antigen to neutralize it  
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seroconversion   point at which antibodies are detectable in serum  
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SDS (MSDS)   safety data sheet (material SDS)  
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systemic signs of inflammation   fever, leukocytes, swollen lymph nodes, rashes, increased pulse  
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local signs of inflammation   redness, heat, pain, swelling  
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