Infectious Disease
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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| Amebiasis (Entamoeba histolytica) pathology | Commensal amoeba. Immigrants, communal living, MSM. Humans only hosts, insects vectors. Excysted in small intestine -> trophs invade large intestine -> ulcers
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| Primary site of extra-intestinal amebic disease is: | Liver (form abscesses up to 15cm). May also disseminate to lung, pleura, pericardium, brain
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| Watery stools with blood, later with necrotic tissue; high fever, tenesmus, N/V are sxs of: | Amebic dysentery
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| Copious, fould smelling, frothy diarrhea +/- blood or pus is sx of: | Giardiasis
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| Plasmodium life cycle | Anopheles mosquito ingests blood with gametocytes -> sporozoites -> infect human -> merozoites in liver -> bloodstream & RBCs -> schizogamy (sexual & asexual forms)
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| Plasmodium forms that produce dormant hepatic sporozoites that cause relaspse | P vivax & P ovale
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| Malaria clinical features | High fevers, rigors, diaphoresis, HSM, attacks Q2-3 days.
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| Toxoplasma gondii forms | Obligate intracellular parasite. Disease-causing troph, latent cyst, infective sporozoite-containing oocysts
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| In PCP pts, recurrent PTX is related to: | prior pentamidine use
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| Most common intestinal helminth worldwide: | Ascaris
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| Ascaris life cycle | Eggs – larvae in sm intestine => bloodstream => R heart => lung => bronchi – swallowed => intestine
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| Frothy, clear-white or yellow-green to gray adherent vaginal discharge, dysuria, vaginal pruritis. Vulvar / cervical erythema. Flagellated protozoa | Trichomonas
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| Leading cause of CHF in Latin America | Chaga disease (T cruzi). Vector assassin bug, active in evening.
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| Trypanosomiasis (Chaga) clinical features | Acute illness 3 wks-3 months with fever, unilateral periorbital edema, LAD, HSM
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| Trypanosomiasis tx | Nifurtimox PO QID x90-120 days
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| African sleeping sickness bug | Trypanosoma brucei
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Created by:
Abarnard
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