Infectious Disease
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| Fungal arthritis etiology | often immunocompromised pts; chronic indolent course; endemic dimorphic fungi in gardeners / occupations w/exp to soil
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| Fungal arthritis: Candida: RFs | surg procedures, joint injections, critical illness (knee, hip or shoulder); IVDUs: spine, SI joints
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| Fungal arthritis: non-candida agents: | Aspergillus, Cryptococcus, Pseudallescheria, dematiaceous fungi
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| In patients with asthma or CF. Thick brown tenacious mucus plugs in sputum | Allergic bronchopulmonary aspergillosis
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| Aspergilloma occurs when: | Fungus colonizes existing cavitary pulmonary lesions. Often invades blood vessels and may present with hemoptysis
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| Disseminated aspergillosis sx/sx | In immunocompromised pt. Pleuritic chest pain, cough, necrotic skin lesions, tissue infarction, wound infections, brain abscesses
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| Dimorphic fungus infecting men in water, by inhalation of mold from rotting wood & soil: | Blastomycosis
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| Blastomyces is found where? | SE, central, & midwest US
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| Common forms of Blastomycosis | Pulmonary most common. Hematogenous usually bone, skin, GU
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| Verrucous, crusted, or ulcerated skin lesions leave a central scar with healing in: | Blastomycosis
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| Coccidioides pathology | Inhalation of highly infectious athroconida (hyphae of the mold form). Common opportunist in HIV patients
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| Coccidiomycosis clinical features | Resp sxs, pulmonary cavitations & abscesses. pain/swelling of knees & ankles, erythema nodosum.
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| People most often affected by Coccidiomycosis / disseminated infection: | African Americans, Filipinos, PG women
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| Respiratory infection from pigeon & other bird droppings in immunocompromised patients | Cryptococcus
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| Cryptococcus clinical features | HA first sx of meninoencephalitis; papilledema. Resp infxns often asymptomatic. 95% of HIV patients are positive
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| Dimorphic fungus in soil contaminated with bat/bird droppings in Ohio & Mississippi River valleys | Histoplasmosis
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| Histoplasmosis clinical features | Resembles flu. Acute dz 9often epidemic): 1-6 weeks, fever & prostration.
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| Diffuse PNA on CXR with few pulmonary symptoms = | Histoplasmosis
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| Progressive disseminated histoplasmosis clinical features: | Involves all organs & is usually fatal. Fever, SOB, wt loss, HSM, bloody diarrhea.
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| Chronic progressive pulmonary histoplasmosis occurs in: | Older patients with COPD
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| Dermatophytosis organisms | Trichophyton, Microsporum, Epidermophyton spp; most common = Trichophyton rubrum
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Created by:
Abarnard
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