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3312 Test #3

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Question
Answer
What are the most effective nonspecific antidiarrheal drugs?   Opiates and Opiate Derivatives  
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Name two opiate/opiate derivative antidiarrheals   Loperamide (imodium) and diphenoxylate with atropine (Lomotil)  
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Would you give antidiarrheal drugs with:Antibiotic associated colitis   No  
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Would you give antidiarrheal drugs with:Relatively severe diarrhea in young children and older adults   Yes  
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Would you give antidiarrheal drugs with:HIV/AIDs associated diarrhea   No  
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Would you give antidiarrheal drugs with:Diarrhea caused by toxic materials   No  
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Would you give antidiarrheal drugs with: Microorganisms that penetrate the intestinal mucosa   No  
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Would you give antidiarrheal drugs with:Chronic inflammatory bowel disease   Yes  
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Would you give antidiarrheal drugs with:severe or prolonged diarrhea for more than 2 days   Yes  
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What is the main adverse effect of antidiarrheal medications   Constipation  
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What type of patient would Alosetron (Lotronex) be used for?   A woman with severe diarrhea-predominant irritable bowel syndrome  
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What are the potential serious adverse effects of Alosetron (Lotronex)?   GI obstruction, perforation, hemorrhage, ischemic colitis.  
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