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Duke PA GI bleed

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Question
Answer
upper bleeds are above   the ligament of treitz  
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upper bleeds are __X more common than lower bleeds   5  
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lower bleeds are below   the ligament of treitz  
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sign of upper GI Bleed   hematemesis  
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coffee ground emesis   old blood from stomach  
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red blood with or without stool, BRBPR   hematochezia  
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dark tarry stools   melena  
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color of melena   black, and nothing else  
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black, sticky, tarry, foul, unforgettable smell   melena  
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__ml of blood can give you melena   50  
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melena usually means that the blood has been in the GI tract for __   12-14 hours  
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medications associated with GI bleed   NSAIDS, ASA, steroids with NSAIDS, Warfarin, Heparin, enoxaparin, clopidogrel  
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__ means that 10% of intravascular volume is lost   resting tachycardia  
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__means that there has been a significant loss (10-20%) of intravascular volume   orthostasis  
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__ means that there has been a loss of 20-40% of intravascular volume   shock  
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brown stool on rectal exam means __   not an acute bleed  
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it can take up to __ for hematocrit to reflect extent of bleeding   2 days  
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things that turn your stool black other than blood   iron, anything with bismuth (pepto, Maalox)  
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mortality rate of upper GI bleed   8-10%  
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most common causes of upper GI bleed   peptic ulcer disease, varices, arteriovenous malformation  
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most common causes of lower GI bleed   diverticular disease, neoplastic disease, colitis (infectious, radiation, ischemic, IBD)  
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anemia with brown stool (guaiac +), iron deficiency anemia   chronic GI blood loss  
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the mainstay of initial treatment for acute GI bleed   resuscitation through large bore IV, with the goal being normal vitals  
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patients who should be transfused   unstable patients (hypotensive, tachycardia), active bleeders, low hemoglobin (Hct >30%, Hgb 10)  
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medical therapy for variceal bleeds   octreotide drip, antibiotics, discontinue all anticoags/antiplatelets  
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medical therapy for suspected upper bleed from peptic ulcer   proton pump inhibitor (pantoprazole drip if severe), discontinue all anticoags/antiplatelets  
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can help to delineate upper from lower source, bloody aspirate helps confirm upper bleed   nasogastric lavage  
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bloody NG lavage with hematochezia   brisk upper GI bleed  
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"negative NG lavage"   bilious return signifying that fluid aspirated from duodenum  
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laceration in the mucosa, usually near the GE junction commonly after retching, 80-90% stop bleeding spontaneously   Mallory-Weiss tear  
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dilated submucosal artery erodes into the mucosa with subsequent rupture of the vessel, bleeding often massive and recurrent   Dieulafoy's lesion  
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acute, painless hematochezia, usually stops spontaneously, risk of rebleed appears to increase with time   diverticular bleeding  
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can help localize bleeding, detects bleeding as small as 0.1-0.5 ml/min, safe, non-invasive, no therapeutic capability   tagged RBC scan  
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