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| Question |
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| Answer |
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| GENERIC NAME |
Dexamethasone sodium phosphate |
| BRAND NAME |
Decadron, Hexadrol |
| CLASS |
Corticosteroid |
| MECHANISM OF ACTION |
Suppresses acute and chronic inflammation. Immunosuppressive effects. |
| INDICATIONS |
Anaphylaxis, spinal cord injury, asthma, croup, elevated ICP, as an adjunct to treatment for shock. |
| CONTRAINDICATIONS |
Hypersensitivity |
| ADVERSE REACTIONS |
HTN, Sodium and water retention, GI bleeding, TB. None from a single dose. |
| NOTES ON ADMINISTRATION |
Pregnancy safety unknown. Protect from heat. Toxicity and side effects with long term use. |
| INCOMPATABILITIES/DRUG INTERACTIONS |
Calcium, Metaraminol. |
| DOSE/ROUTE Adult |
10-100mg IV (1mg/kg slow IV bolus) |
| DOSE/ROUTE Pediatric |
0.25-1mg/kg/dose IV, IO, IM |
| ONSET OF ACTION |
Hours |
| PEAK EFFECTS |
8-12 hours |
| DURATION OF ACTION |
24-72 hours. |
| AZ DRUG BOX SUPPLY RANGE |
8mg optional |
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