Stack #21721
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| VLDL | synthesized by the liver, digested by lipoprotein lipase in peripheral tissue, converted to IDL
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| IDL | endocytosed in liver and degraded by lysosomal enzymes
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| assembly of chylomicons | Tag's assembled in smooth er and use Apo B48 from th rough ER, aquire Apo E and Apo C2 from HDl
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| Bile salts | Cholesterol gets and alpha-hydroxyl group at carbon 7, further oxidized to chenocnolic or cholic acid, conjucated with glycine or taurine
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| cholesterol synthesis | acetyl CoA-mevalonate-isoprene units-squalene-cholesterol
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| rate limiting step in cholesterol synthesis | HMG CoA reductase
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| rate limiting step in bile salt synthesis | 7 alpha hydroxylase
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| HDL | synthesized by liver, major protien is ApoA, trasfers ApoC2 and ApoE to VLDL and chylomicrons
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| Apo CII | activates lipoprotien lipase
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| Apo E | recognition factor for cell surface receptor
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| LDL | endocytosed by peripheral tissues, cholesterol inhibits synthesis of receptors
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Created by:
swohlers
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