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Interactions between genes

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Question
Answer
INDEPENDENT GENES Phenotypes and Example   9:3:3:1 Spotted Horse and Pepper color  
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EPISTASIS (definition)   One gene masks or modifies the expression of the second gene  
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RECESSIVE EPISTASIS Phenotype and Example   9:3:4 Labrador Retrievers  
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DUPLICATE RECESSIVE EPISTASIS Phenotype and Example   9:7 Physa Snail color  
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DOMINANT EPISTASIS Phenotype and Example   12:3:1 Squash color  
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DOMINANT DUPLICATE EPISTASIS Phenotype and Example   15:1 Dominant chicken color  
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MODIFIER GENES Definition and Example   Genes that interact with and affect the expression of another gene (Modify but do NOT mask) Cat color and Horse red pigmenting  
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SUPERIMPOSED MINOR GENES Example   Spotting alleles prevent pigments from reaching some hairs S allele on cats, dogs and horses (more on cats and dogs, less on horses)  
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ENVIRONMENTAL INFLUENCES Types of traits and Examples   Sex-influenced and sex-limited traits (male pattern baldness) Temperature-sensitive traits (Himalayan rabbits and cats)  
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PLEIOTROPY Definition and Examples   A single gene affects multiple traits White eye mutation in Drosophila affects kidney function Lethal white foal disease in horses causes white coat and defective digestive system  
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POLYGENIC TRAIT Definition and Examples   A single trait is affected by multiple genes Eye color in drosophila controlled by 100 different genes Human height  
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CYTOPLASMIC INHERITANCE Definition and Example   Phenotype of offspring determined by genes inherited only from the mother (inherit mitochondria from mother) Leaf color of four o'clock plants  
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MATERNAL EFFECTS Definition and Example   Phenotype of offspring determined by products (mRNAs) from mother's genes Shell coiling in Limnaea  
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GENOMIC IMPRINTING Definition and Types   Genes whose expression is affected by the sex of the transmitting parent paternally imprinted=maternally expressed maternally imprinted=paternally expressed  
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GENOMIC IMPRINTING How?   Results from methylation differences that arise during gametogenesis Heavy methylation inactivates either maternal or paternal allele (epigenic modification)  
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INCOMPLETE DOMINANCE Definintion and Example   All three genotypes have different phenotypes Chicken color, eggplant color, flower color  
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CO-DOMINANCE Definition and Example   Traits associated with BOTH alleles seen in heterozygote (NOT actually dominance) MN and ABO blood proteins  
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Number of possible genotypes (Due to multiple alleles)   genotypes=n(n+1)/2 n=number of different alleles at a given locus  
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ALLELE SERIES Definition and Example   Alles taht produce alternative phenotypes can have serial dominance relatinships C color in rabbits, mice, cats (full-color>part-colored>heat-sensitive>albino)  
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RECESSIVE LETHAL Definition and Examples   Offspring homozygous for lethal allele die 1:2 phenotype, no recessive homozygote Yellow color in mice and Tail-less cats  
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EARLY LETHAL   One class of offspring in crosses is missing  
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POSTNATAL LETHAL Definition and Example   Incomplete skew in birth ratio Spotting (Ov gene) in horses Ratio NOT 1:2:1 or 1:2  
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DOMINANT LETHAL Definition and Example   NO embryonic dominant lethals known because all carriers would die and allele would be lost only detectable if death after reproductive age Huntington's disease in humans  
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EXPRESSIVITY Definition and Example   Extent to which genotype is expressed in an individual (how much phenotype you see) Horse or dog spots (how big)  
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PENETRANCE Definition and Example   Percent of individuals with genotype who show phenotype at all (whether or not you see the phenotype) Polydactyly  
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Created by: kosmorla
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