FSHN 450-2 Lower gi
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| Two types of IBD | Crohn’s and ulcerative colitis
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| IBD | irritable bowel disease
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| Crohn’s disease aka | regional ileitis
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| Crohn’s is inflammation of | the small intestine
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| Crohn’s can also involve | uterus or right side of colon
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| Stenosis | narrowing of lumen
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| Fistula | tunnel from abnormal adherence of mucosal surface to another epithelial tissue
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| Crohn’s malabsorption | blockage results in overgrowth of bacteria , deamination of bile acids and protein -> malabsorption
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| Steatorrhea | fatty diarrhea
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| Tenesmus | sudden need to use the bathroom
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| ___ affects ___% of people w/ Crohn’s | malnutrition, 25-85%
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| oxalate kidney stones and why w/ Crohn’s | undigested FAs bind to Ca so Ca unavailable and can’t bind oxalate
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| methotrexate | immunosuppressant for IBD that inhibits folic acid metabolism and affects bone marrow
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| antidiarrheal drug side effect | anti-coloneric= dry mouth, dry eye
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| methotrexate side effects | megaloblastic anemia
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| immunosuppressant side effects | antibodies against TNF-a, abdominal sx, increase risk of infection
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| sulfasalazine side effects | (anti-inflammatory) allergic reactions, gastritis, better/new forms
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| what’s lost w/ diarrhea? | magnesium, potassium, sodium
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| B12 deficiency is often involved when | terminal ileum is involved
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| How to get folic acid? | must receive via injection
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| What foods are high in oxalate? | dark greens and whole wheat
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| Omega 3s and IBD | inconclusive but may prolong remission w/ 3-5g/day
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| Ileostomy MNT | fluid and sodium balance, B12
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| IBS medical treatment | loperimide/narcotics= slow transit time, somatostatin/GLP antisecretory
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| IBS is a ___ not a ___ | functional disorder, disease
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| IBS aka | spastic colon
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| IBS symptoms | bloating, gas, cramping, pain, diarrhea, constipation, mucous in stool, tenesmus
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| Diagnosis of exclusion | IBS, if barium enema, CT scans, endoscopic exam all negative
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| Rome II criteria for Dx of IBS | relieved by defecation, onset associated w/ change in form of stool, onset associated w/ change in frequency of stool
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| Fodmaps | fermentable oligo, di, mono saccharides and polyols
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| Diverticulosis diet | adequate fiber and fluid intake
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