ABO discrepancies
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
|
|
||||
|---|---|---|---|---|---|
| Group 1 discrepancy | Weak or missing ag due to immunocompromised status
🗑
|
||||
| Group 2 discrepancy | Missing antigens due to disease or rare subgroup
🗑
|
||||
| Group 3 discrepancy | Unexpected antigens due to disease or extra proteins
🗑
|
||||
| Group 4 discrepancy | Unexpected antibodies due to infection or alloantibodies
🗑
|
||||
| Group 1 missing ab resolve | Determine diagnosis, incubate at room temperature 15 minutes, incubate at 4 to enhance cold ab
🗑
|
||||
| Group 2 missing ag resolve | Room temperature incubation to enhance weak rxn, pretreat with enzymes, check for acquired B
🗑
|
||||
| Group 3 unexpected ag resolve | Wash to resolve forward testing, saline replacement, wash to remove whartons jelly
🗑
|
||||
| Group 4 unexpected ab resolve | DAT at cold temp for cold alloantibodies, Dolichos biflorus to detect A2 our other A subgroup, ab screen/panel to detect alloantibodies
🗑
|
||||
| Forward typing discrepancies | Missing ag due to subgroup/disease, extra ag due to disease or protein, mixed field die to transfusions or transplant
🗑
|
||||
| Reverse typing discrepancies | Missing ab in newborns or elderly, extra ab due to anti-A1 alloantibodies, passive immunity
🗑
|
||||
| Caucasian ABO frequencies | A 41%, B 10%, O 45%, AB 4%
🗑
|
||||
| Black ABO frequencies | A 27%, B 20%, O 49%, AB 4%
🗑
|
||||
| Asian ABO frequencies | A 28%, B 26%, O 40%, AB 6%
🗑
|
||||
| Enzymes enhance | Rh, Kidd, Lewis, P
🗑
|
||||
| Enzymes destroy | Kell, Duffy, MNS (Lutheran)
🗑
|
||||
| Cold antibodies | Lewis, P, MN, Lu-a
🗑
|
||||
| Warm antibodies | Rh, Kell, Duffy, Kidd, SsU, Lu-b
🗑
|
||||
| Labile in vivo and in vitro | Kidd
🗑
|
||||
| Expression lost during pregnancy | Lewis
🗑
|
||||
| Resistant to P. vivax | Fy (a-b-) cells
🗑
|
||||
| R1 | DCe, common
🗑
|
||||
| R0 | Dce, common in blacks, otherwise rare
🗑
|
||||
| R2 | DcE, 20% or less in all pops
🗑
|
||||
| RZ | DCE, extremely rare
🗑
|
||||
| r | dce, rare in Asians, otherwise common
🗑
|
||||
| r' | rCe, rare
🗑
|
||||
| r" | dcE, extremely rare
🗑
|
||||
| rY | dCE, extremely rare
🗑
|
||||
| Hydatid cyst fluid | Has anti-P activity
🗑
|
||||
| Donath-Landsteiner test | For paroxysmal cold hemogloburia. Detects anti-P IgG
🗑
|
||||
| Hematocrit increase per unit RBC | 3%
🗑
|
||||
| Hemoglobin increase per unit RBC | 1g/dL
🗑
|
||||
| Whole blood indications | Symptomatic anemia with large volume deficit
🗑
|
||||
| RBC indications | Symptomatic anemia
🗑
|
||||
| Plasma indications | Deficiency of labels and stable plasma coagulation factors
🗑
|
||||
| Cryoprecipitate pooled indications | Hypifibrinogenemia, factor Xlll deficiency
🗑
|
||||
| Factor Vlll indications | Hemophilia A
🗑
|
||||
| Basic evaluation of transfusion rxn | Clerical error check, hemolysis check, DAT, retype
🗑
|
||||
| Increase in platelets per unit | 20,000-40,000
🗑
|
||||
| Factor IX | Hemophilia B
🗑
|
||||
| RhIgG dose calculation | Fetal cell % x 50 \ 30 plus one vial
🗑
|
||||
| Refractive mixed field agglutination | Anti-Sda
🗑
|
||||
| Warm autoimmune hemolytic anemia | Often associated with anti-e
🗑
|
||||
| Neutralize Lea | Use saliva containing secretions of Lea
🗑
|
||||
| Complement dependant antibodies detection | Serum stored at 4C for less than 48 hours
🗑
|
||||
| HTLA | High titer low avidity antibodies
🗑
|
||||
| NAT testing for | HIV, HCV
🗑
|
||||
| Vaccines with no deferral period | Recombinant vaccines
🗑
|
||||
| Acceptable time limit for whole blood collection | 20 minutes
🗑
|
||||
| Placid/clopidogrel | Destroys platelets
🗑
|
||||
| Waiting period between autologous donations | 3days
🗑
|
||||
| Cryoprecipitate expiration post thaw, post pooling | 4 hours
🗑
|
||||
| RBCs retained after leukoreduction | 85%
🗑
|
||||
| Techniques for weak D testing | 37C incubation +IAT
🗑
|
||||
| Wiener Rh theory | Single-locus theory, multiple alleles determine surface Rh antigens
🗑
|
||||
| Weak D is missed by | gel testing, because ithe ABD card lacks a 37C and AHG phase
🗑
|
||||
| U antigen | Part of the MNS group, no dosage, not affected by enzymes, IgG class warm significant antibody
🗑
|
||||
| Poorly expressed at birth | Lewis, Lutheran, I, ABO
🗑
|
||||
| strong expression at birth | Rh, Kell, Duffy, Kidd, MNS
🗑
|
||||
| Clinically significant antigens in generally non-significant groups | Lub, SsU
🗑
|
||||
| McLeod phenotype | Lacks Kell group. Associated with CGD
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
Enebergall
Popular Medical sets