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HIV & AIDS, Cancer,

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Term
Definition
Antiretroviral Therapy   Medications to specifically combat the retrovirus.  
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B cells   Lymphocytes that originate in the bone marrow.  
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Opportunistic infections (OI)   Infections or cancers that do not generally cause disease in a person with a normal immune system. Commonly found in later stages of HIV or part of diagnosed  
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Prophylaxis   Medication given to prevent infections.  
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Retrovirus   One of a large group of RNA-based viruses that tend to infect immunocompromised persons.  
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T cells   Lymphocytes that originate in the thymus (T lymphocytes)  
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Viral load   Amount and strength of the HIV virus in an individual ; also called HIV-RNA  
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Adjuvant therapy   Assisting or enhancing therapy given, especially in cancer to prevent further growth or pain; therapy used which was originally intended for another purpose.  
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Anaplastic cell   A cell which lacks orderly growth arrangement, and does not function normally; these cells are found in malignant tumors.  
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Antineoplastic   An agent that inhibits the growth of malignant cells.  
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Apoptosis   cell self destruction  
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Benign   harmless, not malignant  
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Biopsy   removal of a sample of body tissue or fluid for diagnostic examination, usually microscopic; most often used to detect the presence of cancer.  
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Biotherapy   The use of biologic response modifiers(BRM) in cancer treatment.  
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Blastoma   Blastic tumors are malignant tumors of immature or embryonic tissue. (found in children) Examples Nephroblastomas- kidney, medulloblastomas- brain and retinoblastomas- eye tumors.  
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Cancer   a malignant growth, neoplasm, carcinoma. is characterized by excessive growth (proliferation) of cells that lack the capabilities of normal cellular function.  
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Carcinogen   An agent that causes cancer.  
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Carcinogenessis   The transformation of a normal cell into a malignant cell.  
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Carcinoma (CA)   The largest group of cancer. develop from epithelial tissues that line skin, glands, gastrointestinal (GI), urinary, and reproductive organs. Cancer, a malignant neoplasm (new growth)  
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Cachexia   Severe ill health and malnutrition; debilitated state.  
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Chemotherapy   Use of chemical agents to destroy cancerous cells  
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Cryosurgery   Removal of tissue by destroying it through freezing.  
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Cytology   the study of cells  
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Eletrocauterization   destruction of malignant tissues by burning.  
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Fulguration   destruction of malignant tissues by high- frequency current  
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Histology   The study of tissues  
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Immunotherapy   Biotherapy uses the immune system directly or indirectly against cancerous tumor cells via biological response modifiers (BRMs). biological response modifiers  
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Leukemia   Malignant disease of blood forming organs may be classified as acute or chronic and also in relationship to the specific blood cell affected, as acute lymphoid (lymphocytic) myelocytic, or granulocytic leukemia.  
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Malignant   deadly; tending to become progressively worse.  
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Metastasis   Transfer of disease organisms or cells from one organ or body part to another not directly connected with it; often refers to cancer cells or TB  
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Myelosuppression   Reduction in bone marrow function  
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Neoplasm   Tumor, new growth( may be benign or malignant); often refers cancer  
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Oncogene   A gene that causes cancer  
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Oncology   Study of tumors and the study of cancer  
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Remission   Indicated by absence of all signs of a disease such as remission of cancer. Dose not prove a cure of the disease.  
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Replication   Reproduction of cancer  
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Scarcoma   Connective tissue tumors. that develop from connective or supportive tissues, such as Cartilage, Bone, Fat, Muscle, Bone marrow, and Blood vessels Example gliomas and neuroblastomas of the brain osteosarcoma, and Ewing's sarcoma, and leiomyosarcoma.  
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Signs   Objective evidence of disease that another person can note (as opposed to symptom, which only the client can describe).  
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Symptoms   Indications of disease or illness that are noticed by the client e.g fatigue, nausea, or malaise; subjective observations  
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Allergen   A substance capable of producing hypersensitivity (allergy)  
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Allergy   A state in which the body is hypersensitive to a substance, usually a protein  
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Anaphylaxis   Serious state of shock resulting from hypersensitivity to an allergen ; also called anaphylactic effect.  
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Autoimmune disorder   Disorder in which the body fails to recognize its own cells as "self" and begin to destroy them  
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Eczema   An inflammatory skin rash, characterized by itching, redness, weeping, oozing, and crusting, and later by scaling.  
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Histamine   A major chemical mediator involved in the allergic response An amine found inall body tissues that stimulates dilation of small blood vessels and production of gastric juice.  
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Hives   swollen patches on the skin as a result of an allergic reaction  
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Induration   A hardened place, a lump as in the skin in a positive reaction to a TB test  
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Immunogen   A substance capable of initiating or stimulating an immune response  
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Immunosuppression   Referring to deliberate suppression of the natural immune system, as in chemotherapy for cancer  
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Leukotrienes   Chemical mediators which are 100 to 1000 times more potent than histamine in causing bronchospasm. released by mast cells they initiate the inflammatory response causing contraction of smooth muscle , constriction of the bronchi, and secretion of mucus  
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Non--organ specific   A disease that affects one or more organs  
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Organ-specific   Having an effect only on a particular organ  
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Urticaria   An allergic skin reaction characterized by superficial wheals and often accompanied by severe itching; also called HIVES  
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Wheals   A smooth, slightly elevated skin area, usually pale in the center with a reddened periphery, often accompanied by severe itching when caused by an allergic reaction; small elevation caused by injection of an intradermal medication, such as the PPD  
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Monoclonal Antibodies( MOAB)   Produced by genetically fusing cancer cells with normal cells. They are highly specific antibodies that seek out, and bind to specific targets on cancer cells causing apoptosis  
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