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WVSOM -- Pulmonary Circulation

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Question
Answer
What is the organization of pulmonary circulation?   pulmonary artery, branch with airways, mesh of capillaries at the respiratory bronchioles, pulmonary venules, and pulmonary veins  
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What is the flow and pressure of pulmonary circulation?   high flow, low pressure  
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What happens to alveolar vessels when they are exposed to high alveolar pressure?   contract  
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What happens to alveolar capillaries when the alveolar pressure is low?   the alveolar capillaries dilate  
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What inspiration do to extra-alveolar vessels?   pulls them open by radial traction  
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What is the only organ to receive all of the cardiac output?   lungs  
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Why is there little smooth muscle in the lung?   only enough to direct blood to all areas of the lung.  
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What determines blood flow in the lung?   passive hydrostatic forces  
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What are the two types of vessels in the lung?   alveolar vessels (capillaries exposed to alveolar gases) and extra-alveolar vessels  
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What determines the diameter of extra-alveolar vessels?   lung volume  
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What determines the caliber of alveolar vessels?   balance between internal and alveolar pressures  
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Which vessel can collapse if alveolar pressure is large enough?   pulmonary capillaries  
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What is pulmonary vascular resistance compared to systemic vascular resistance?   pulmonary vascular resistance is 1/10th of the systemic vascular resistance  
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What will happen to pulmonary vascular resistance if the arterial or venous pressure increases?   pulmonary vascular resistance decreases  
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Why does pulmonary vascular resistance reduce?   recruitment and distension of other pulmonary capillaries  
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When does pulmonary vascular resistance increase?   with low or high lung volumes  
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Why does pulmonary vascular resistance increase at high lung volumes?   the high volumes put a lot pressure on the capillaries stretching them increasing resistance  
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Why does pulmonary vascular resistance increase at low lung volumes?   the resistance is from the extra alveolar vessels because there is less radial traction to open up these vessels.  
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Where is pulmonary blood flow grater?   lung base  
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Where is the greatest distension of capillaries?   Zone 3 (base)  
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Where are the vessels most compressed?   zone 1 (apex)  
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What is hypoxic vasoconstriction?   blood flow in the lung is directed away from the hypoxic area of the lung. Usually is regional  
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What happens in generalized hypoxia?   elevates pulmonary pressure by large areas of hypoxia which results in edema.  
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Why is keeping the alveolar walls problematic in keeping them dry?   they are very thin  
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What causes fluid leakage?   Hydrostatic pressure and the surface tension  
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What causes fluid to stay in the capillaries?   colloid osmotic pressure and lymph drainage  
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Where is fluid in early edema?   engorgement of interstitial spaces  
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Where is fluid in late edema?   fluid in alveoli  
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What are the metabolic functions of the pulmonary system?   conversion of angiotension I to Angiotension II, serotonin uptake and removal of Norepi, leukotrienes and prostaglandins  
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