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Stack #176271

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
Risk factor: Diabetes. Services?   Eye, foot exams; urine tests  
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Risk factor: Drug use. Services?   Hep immunizations; HIV, TB tests.  
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Risk factor: Alcoholism. Services?   Pneumococcal, Influenza immunizations; TB test  
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Risk factor: Overweight. Services?   Blood sugar tests for diabetes.  
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Risk factor: Homeless, recent immigrant, inmate. Services?   TB test  
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Risk factor: High-risk sexual behavior. Services?   HIV, hep B, syphilis, gonorrhea, chlamydia tests.  
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Reportable diseases?   Hep, Hep, Hep, Hooray, the SSSMMART Chick is Gone! Hep A/B/C, HIV, Salmonella, Shigella, Syphilis, Measles, Mumps, AIDS, Rubella, TB, Chickenpox, Gonorrhea  
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Leading causes of death in the US for infants   congenital anomalies, sort gestation/low birth weight, sudden infant death syndrome, maternal complications of pregnancy, respiratory distress syndrome  
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Leading causes of death in the US for ages 1-14   injuries, cancer, congenital anomalies, homicide, heart dz  
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Leading causes of death in the US for ages 15-24   injuries, homicide, suicide, cancer, heart disease.  
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Leading causes of death in the US for ages 25-64   cancer, heart dz, injuries, suicide, stroke.  
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Leading causes of death in the US for ages 65+   heart dz, cancer, stroke, COPD, PNA, influenza  
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Stress affects   Induce production of free fatty acids, 17-OH corticosteroids, lipids, cholesterol, catecholamines; Affects water absorption, muscular tonicity, gastrocolic reflex, mucosal circulation.  
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Differential diagnosis of sexual dysfunction   Drugs (antihypertensives, neuroleptics, SSRIs, ethanol), Diseases (depression, diabetes), Psychological (performance anxiety)  
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5 heart block   Lyme dz, salmonella typhi (=typhoid), chagas dz (whipple's), legionella, diphtheria  
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reiter's syndrome   chlamydia, shigella, yersinia, crohns, irrit.bowel dz  
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low complement cryoglob. (bugs)   "I AM HE": influenza, adenovirus, mycoplasma, hep c, EBV . (=5 vasculitides assoc with Subacute Bacterial Endocarditis)  
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drug induced SLE   "HIPPE": hydralazine, isoniazid, procainamide, penicillamine, phenytoin, ethosuximide  
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drugs that blast BM   "ABCV": AZT, benzene, chloramphenicol, vinblastine  
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comma shaped bugs   vibrio, campylobacter, listeria, H. pylori  
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corynebacter   chinese letters  
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giardia lamblia   crescent shaped protozoa  
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TB Rx's   "RESPIre": Pyrazinamide, rifampin, ethambutol, isoniazid, streptomycin  
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6 low complement associated nephrotic syndromes (vascultides)   Serum sickness, PSGN, SLE, SBE, Cryoglobulinemia, MPGN II (membranoproliferative GN)  
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Induce P450   "Really Quiet Bats Go Camping": Rifampin, Quinidine, Barbiturate, Alcohol (chronic), Tetracycline, Sulfa drugs, Griseofulvin, Carbamazepine  
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Inhibit P450   "I'd SMACK Q": INH, Dapsone, Spironolactones, Macrolides, Amiodarone, Cimetidine, Ketoconazole, Quinolones  
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P450 dependant   "WEPTD": Warfarin, Estrogen, Phenytoin, Theophyline, Digoxin  
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Neutrophil deficiency   CGD (chronic granulomatous dz)= NADPH-oxidase deficiency (X linked recesive)  
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Side efects of Statins   Myositis, hepatitis, elevated liver enzymes  
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Painful genital lesions   herpes, chancroid (hemophilus ducreyi), lymphogranuloma inguinale (venereum, chlamydia), granulom inuinale associated with Donovini  
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4 hormones with disulfide bonds   "PIIG": prolactin, inhibin, insulin, growth hormone  
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Hookworms   "NEATAS": necatur americanis, enterobius vermicularis, anklostoma duodenale, trichuris trichurium, ascaris lumbricoides, strongyloides  
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x-linked enzyme deficiencies   G6PD (=MC), CGD (NADPH oxidase defic.), Pyruvate DH deficiency, Fabry's, Hunter's, Lesh-Nyhan. (are usualy AR)  
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Screen newborns   "Please Check B4 Going Home": PKU, CAH (Congenital Adrenal Hyperplasia), Biotidinase defic., Galactosemia, Hypothyroidism  
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Actions of Steroids   "KIIISS": kils Th cels and eosinophils, inhibit macrophage migration, ingibits phospholipase A2, inhibits mast cel degranulation, stabilizes (tighten) endothelium, stimulate cell protein synthesis  
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cause monocytosis   salmonella (typhoid), TB, EBV (MC), listeria, syphilis, CMV  
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Ecoli is the most common cause of ?   "AAASUC": abdominal absces, ascending cholangitis, apendicitis, spontaneous bacterial peritonitis, UTI, cholecystitis  
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one dose trx for chlamydia   azithromycin  
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"Big Mama" Anaerobes   Strep Bovis, Clostridium melanogosepticus, Baceroides Fragilis  
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"Big Mama" Trx for anaerobes   clindamycin, metronidazole, cefoxitin  
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low volume state (serum)   low K/Na/Cl, hi pH/BP  
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one dose Trx for gonorhea   "CCCCOG": ceftriaxone, cefixime, cefoxitin, ceprofloxacin, ofloxacin, gatifloxacin  
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Psammoma bodies   "PSaMMoma" =calcified cancers: Papilary CA of thyroid, Serous cystadenoma of ovary, Meningioma, Mesothelioma  
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Urease positive bacteria   "PPUNCH": proteus (struvite stones=90%, swarming motility), pseudomonas, ureaplasma urealyticum, nocardia spp., cryptococus neoformans, helicobacter pylori  
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4 indications for PUD surgery   "IHOP": intractable pain, hemorage, obstruction (fr scarring), perforation  
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cardiac fibrosis   adriamycin, phen-fen  
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MCC of any ...penia   viral, drugs (ABCV-C: azt, vincblastine, chemo, benzene, chloramphenical)  
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salmonela typhi triad   hi fever, intestinal fire, rose spots (rash)  
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drugs that cause myositis   "RIPS": rifampin, inh, prednisone, statins  
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7 encapsulated bacteria (gram negative)   "Some Strange Kilrs Have Prety Nice Capsules": salmonela, strep PNA, klebsiela, h. influenza, pseudomonas, neiseria, citrobacter  
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jones criteria (rheumatic fever)   "PECCS": polyarthritis, erythema marginatum, carditis, chorea, Subcutaneous nodules  
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eosinophilia   "CAPAN": neoplasms, alergies/asthma, adison's dz, colagen vasc. dz, parasites  
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risk factor for primary liver ca (hepatoma)   "HAVE CASH BS": hep B/C, aflatoxin, vinyl chloride, EtOH, carbon tetrachloride, anyline dyes, smoking hemochromatosis, benzene, schistosomiasis mansoni  
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9 live vacines   "MR OR Smal Blistery Yelow Vesicles": Measles, Mumps, Rubela, Oral Polio (Sabin), Rotavirus, Small Pox, BCG Yelow Fever, Varicella  
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IgA Nephropathies   henoch-schonlein purpura, berger's, alport's  
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autoimune hemolytic anemia   "PACS PAD": PTU, alpha-methyldopa, cephalosporins, sulfa, PNC, antimalarial , dapsone  
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autoimune thrombocytopenia   ASA, heparin, quinidine  
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drugs containing sulfa   sulfonamides, sulfonylurea, celbrex-celecoxib =COX2 specific (viox-rofecoxib=COX2 spec has NO sulfa)  
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inhibit dihydrofolate reductase   pyremethamine/sulfadiazine, trimethoprim/sulfamethoxasole  
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MI enzymes   TPI= appears in 2h, peaks in 2 d, gone in 7 d; CKMB= appears in 6h, peaks in 12 h, gone in 24h; LDH1=appears in 1d, peaks in 2 d, gone in 3d  
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siver stains   "BC Lawyers Charge Hourly": bartonela henselae (Lymph nodes), candida (yeast), legionela, pneumocystis Carinii, H. pylori  
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drugs that cause pulm fibrosis   "BBAT": bleomycin, busulfan, amiodarone, tocainide  
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macrophage deficiency   chediak-higashi, NADPH-oxidase deficiency  
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Side efect of loops and thiazides   "OHHHH": ototoxic, hyperglycemia, hyperuricemia, hypokalemia, hypovolemia  
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the only 3 pansystolic M's   inc on expir, decr on inspir: MR, VSD; incr on inspir: TR  
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7 palms and soles rashes   "TRACKSSS": TSS, RMSF (rocky mtn spotted fever), coxsackie A (hand/foot/mouth dz), kawasaki, scarlet fever, syphilis, sSSS(staph scald skin syndrome= exfolitin)  
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every restrictive lung dz and low volume state   tachypnea, low pCO2, low pO2, hi pH  
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2nd messengers: cAMP, cGMP   2nd messengers: cAMP=symp., CRH. cGMP=parasymp.  
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2nd messengers: IP3/DAG   NeuroTransmiter, GHRH, all hypothal. horm. xc CRH, smooth muscle by contraction  
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2nd messengers: cAlcium/calmodulin   smooth musc. contr by distention  
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2nd messengers: calcium   gastrin  
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2nd messengers: tyrosine kinase   insulin, al GF's  
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2nd messengers: NO   nitrates, viagra, ANP, LPS (endotoxin)  
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T and B cel deficiency   WAS (wiskot Aldrich), SCID, CVID, HIV, HTLV1  
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WAS (wiskot Aldrich)   thrombocytopenia, IL4 infx, eczema, decr IgM (IgE?)  
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SCID   framshift/nonsense mutation, adenosine deaminase defic; T>B; bact. and fungal infxns  
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CVID   late onset, frameshift/misense mutation; tyrosine kinase defic  
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HIV, HTLV1   T>B, CD4 rich; brain testicles, cervix, blod vesels  
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ETC poisons:   complex I=amytal, rotenone; complex II= malonate ; complex III=antimycin D; complex IV= CN-, CO, chloramphenical; complex V=oligomycin  
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ETC chemical uncouplers   dnp, free fatty acids, aspirin (a physical uncoupler)  
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4 sources of acid (Renal)   plasma, urea cycle, collecting ducts, gutaminase  
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ETC poisons:complex I=   amytal, rotenone;  
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ETC poisons:complex II=   malonate ;  
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ETC poisons:complex III=   antimycin D;  
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ETC poisons:complex IV=   CN-, CO, chloramphenical;  
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ETC poisons:complex V=   oligomycin  
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one dose trx hemophilus ducreyi   azithromycin 1 gr po, ceftriaxone 250 mg im,  
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one dose trx candidiasis   ketoconazole 150 mg  
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one dose trx vaginal candidiasis   1 pill of diflucan  
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one dose trx trichomonas   metronidazole 2 gr  
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one dose trx gardnerella   metronidazole 2 gr  
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to break down glycogen, 4 enz.   phosphorylase (Pi), debranching enz, alpha-1,6-glucosidase, phosphatase, alpha 1,4-glucosidase  
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to make glycogen, 2 enz   glycogen synthase, branching enz (=glycogen alpha-1,4;alpha-1,6 glycosyl transferase)  
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obstructive vs restrictive pulmonary dz   obstructive= hi pO2/N, or hi pCO2, low pH. (leads to resp. acidosis) restrictive = low pO2, low pCO2, hi pH  
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6 places of TCA where aa's feed in/out   pyruvate- gly, ala,ser; acetyl coA- Mr.PITT (phe, iso, thr,tyr) + lys, leu; alpha-KG - glu, gln; succinyl coA- phe, tryp, tyr; fumarate-pro; oxaloacetate- asp,asn  
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4 steps of beta oxidation   1. oxidation (7 NADH/21 ATP). 2. Hydration. 3. oxidatio(7 FADH/14 ATP). 4. thiolysis (8 AcCoA/ 96 ATP). ***total 131 ATP-2 to bring it in.  
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4 H's produced by small cell CA   ACTH, ADH, PTH, TSH, (ANP)  
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viruses directly cause CA   PAPILLOMA, EBV, HBV,HCV, HIV  
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tPA 20mg iv push, 40mg drip. give inhibitors.   aminocaproic acid  
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streptokinase 750K iv push, then 750K drip. give inhibitors.   aminocaproic acid  
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warfarin. give inhibitors.   vitK  
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heparin. give inhibitors.   protamin sulfate  
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urokinase.   used only for feeding tubes, fistulas, etc.  
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anticardiolipin   SLE  
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anti-topoisomerase   PSS (Progressive Systemic Sclerosis)  
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anti-TSH receptors   Graves  
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anti-hair follicle   allopecia areata  
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anti-myelin receptor   MS  
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anti-melanocyte   viteligo  
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anti-ACH   MG  
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anti-ribonuclear protein   Mixed CT dz (MCTD)  
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anti-parietal cell receptor   pernicious anemia (ab's to intrinsic factor)  
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anti-epidermal anchoring protein receptors   pemphigus vulgaris (positive Nikolsky, ab's to intercellular jntn of epidermal cells)  
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anti-epidermal BM protein   bullous pemphigoid,(IgG subepidermal blisters, oral etc.)  
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anti-thyroglobulin   hashimoto's  
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anti-microsomal   hashimoto's  
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anti-smooth muscle   scleroderma  
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anti-scl70   scleroderma  
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anti-rho (SS-A)   sjogren's  
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anti-la   sjogren's  
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anti-proteinase   wegener's  
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clot in front of renal artery   renal artery stenosis  
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clot off whole renal artery   renal failure  
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clot in renal papilla   papillary necrosis  
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clot off renal medulla   interstitial nephritis  
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clot off pieces of nephron   focal segmental GN, HIV, drug use assoc.  
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clot off lots of nephrons   RPGN  
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MC nephrotic dz in adults   membranous GN  
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MC renal dz in blacks/hispanics   focal segmental GN  
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MC renal mass   a cyst  
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MC malignant renal tumor in adults   adenocarcinoma  
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MC malignant renal tumor in children   wilm's tumor  
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MCC leading to RPGN   goodpasteurs  
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alopecia areata   patch of hair  
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alopecia totalis   entire head bald  
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alopecia universalis   entire body hairless  
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pulmonary infiltrate eosinophilia (PIE) syndrome   "NASSA": necator americanus, ascaris lumbricoides, schistosomiasis, strongyloides, ankylostoma duodenale  
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2 enzymes used by B12   homocystine methyl transferase, methyl malonyl mutase  
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mitochondrial inheritance   NO male transmission, ALL  
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increased susceptibility to pseudomonas and staph infxs   burn pts, CF pts, DM pts, neutropenic pts (cover 1x for S. aureus during 1st wk, cover 2x for pseudomonas after 2nd wk)  
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cause of widened S2   (incr pO2, incr vol in R ventricle). 1. blood transfusion. 2. giving O2. 3. R side failure. 4. pregnancy (incr vol). 5. iv fluids. 6. ASD. 7. deep breathing.  
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8 cavities of blood loss   "PIMP TRAP": pericardium, intracranial, mediastinum, pleural cavity, thighs, retroperitoneum, abdominal (=big), pelvis (=deep)  
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penicillin   gram positive, bone marrow suppression; simple anaerobes; #1 cause of anaphylax; interstitial nephritis; nonspecific rashes; as haptens->hemolytic anemia.  
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negative-stranded RNA   prodromal period b4 sxs=1-3 wks b/c must switch to positive stranded before replication  
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positive-stranded RNA   sxs within 1 wk or less (xc these negative stranded: hanta, ebola, yellow fever)  
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5 cofactors for dehydrogenase complex   "Tender Loving Care For Nancy": TPP (thiamin-B1), lipoic acid (B4), CoA (pantothenic acid- B5), FAD (Riboflavin-B2), NAD (Niacin-B3).  
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x-linked inheritance (all are x-recessive, xc one)   bruton's agammglobulinemia, CGD (NADPH defic.), duchenne, color blindness, G6PD, hemophilia, lesch-nyhan, vitamin resistant rickets (x-linked dominant)  
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B-cell deficiency   bruton's agammaglobulinemia (tyrosine kinase deficiency), SCID (T-cell overlap), WAS (T-cell overlap), CVID (common variable immune defic., tyrosine kinase defic), leukemias, lymphomas, job-buckley syndrome (T-cell overlap)  
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4 itchiest rash   "SLUD": scabies, lichen planus, urticaria, dermatitis herpetiformis  
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I-myc   small cell lung CA, promyelocytic leukemia (Burkitt's lymphoma)  
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c-myc   small cell lung CA, promyelocytic leukemia (Burkitt's lymphoma)  
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N-myc   neuroblastoma, small cell lung CA  
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c-abl   CML, ALL  
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c-myb   colon CA, AML  
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c-sis   osteosarcoma, glioma, fibrosarcoma  
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c-erb B2   epidermal growth factors receptors  
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CSF-1   breast  
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erb-B2   breast CA, ovarian, gastric  
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ret   medullary CA of thyroid, MEN II/III, papillary CA  
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Ki-ras   lung CA, colon CA  
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bcl-2   Burkitts, follicular lymphoma  
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erb   retinoblastoma  
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ranson's criteria of acute pancreatitis   at admission "GALAW": glu>200, age>55, LDH>350, AST>250, WBC>16,000. at less than 48 hrs "CHOBBS": calcium<8mg/dl, hct drop of>10%, O2<60 (PaO2), base deficit>4, BUN>5, sequestration>6L  
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hormones produced by placenta   "HI HOPE": hCG, inhibin, human placental lactogen (HPL), oxytocin, progesterone, estrogen  
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pilocarpine   CF, glaucoma (painful, red, teary eye)  
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causing dysgeusias (taste disorders)   metronidazole, clarithromycin, Zn deficiency  
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Rashes associated with cancer: seborrheic keratosis (waxy warts)   colon ca or HIV if sudden increase in #. nL with aging.  
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Rashes associated with cancer: dermatomyositis (violacious, heliotropic rash, malar area)   colon ca  
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Rashes associated with cancer: akanthosis nigricans (dark lines in skin folds)   any visceral ca, end organ damage  
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carcinoid syndrome (triad), measure what,   flushing, wheezing diarrhea (measure serotonin 5-HIAA; comes from pancreas, ileum)  
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AVMs   "HEAL": heart (PDA), elbow (fistula from dialysis in renal dz), abd/brain (von hippel lindau, clot off with coils, increased incidence of renal cell CA--chr3), lungs (osler-weber-rendu syndrome).  
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HDL carries   "CEAL": L-CAT, E, C-II, Apo-A  
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VLDL carries   B-100, E, C-II, ApoA  
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IDL carries   B-100, E, CII  
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LDL carries   B-100  
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chylomicrons take TGs from GI to   liver (25%), endothelium (75%)  
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erythema marginatum   little red spots with bright red margins, sandpapery, RF - Jones criteria ->strep pyogenes  
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Measles   morbiliform rash, preceded by cough, conjuctivitis  
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roseola   fever 2 days, sop, rash pops up= rash after fever (=HHV6)  
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erythema nodosum   anterior aspect of leg, redness, teder nodules  
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erythema multiforme   red macules, target lesions, allergy, viruses, severe = Toxic Epidermal Necrolsis (skin peels off); mild = stevens johnson syndrome; mild= virus (MCC), drugs (Sulfa)  
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seborrheic dermatitis   scaly skin with oily shine on hairline  
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seborrheic keratosis   stuck on "warts"  
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psoriasis   HLA B27, extensor surfaces, silvery white plaques, scaly skin, pitted nails  
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varicella zoster   stages- red macules, papules, vesicles, pustules, then scabs; different stages at same time (=HHV3)  
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dermatitis herpetiformis   rash/blisters on ant. thigh, assoc. with diarrhea 2/2 celiac sprue flare up  
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typhoid fever (salmonella)   rose spots assoc. with "intestinal fire"  
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dermatomyositis   heliotropic rash  
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erysipelas   reddened area on skin with raised borders; does not blanch  
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tinea cruris   redness, itchy groin  
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pityriasis rosea   herald patch; dr skin patches that follow skin lines, (HHV7)  
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Tinea versicolor   hypopigmented macules on upper back in "V" pattern (upside-down Christmass tree); Trx=griseofulvin  
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Scabies   linear excoriations on belt line and finger webs, etc. Trx: Lindane, or Permethrin.  
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T-cell deficiency   DeGeorge's (hypokalemia, 3 & 4 pharyngeal pouch, deletion of chr22), HIV (also B-cell, but less so)  
🗑
Lipoprotein transports: chylomicron   takes TGs from GI to liver and endothelium  
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Lipoprotein transports: VLDL   takes TGs from liver to adipose  
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Lipoprotein transports: IDL   takes TGs from adipose to tissue  
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Lipoprotein transports: LDL   only one to carry cholesterol  
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Lipoprotein transports: excessive TGs   xanthelasma- eyelids/-brows  
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Lipoprotein transports: excess cholesterol   xanthoma-elbows  
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Lipoprotein transports: VLDL   is the only one made in the liver  
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Lipoprotein transports: IDL and LDL   are break down products of VLDL  
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hemophilus influenza   "pleomorphic" gram negative rod; "school of fish"; (Type A=80%, non-encapsulated, noninvasive, 2nd MCC of sinusitis/otitis/bronchitis). (Type B=20%, encapsulated-polyribosyl phosphate in capsule, IgA Protease, invasive dz, #1 cause of eiglotitis, stridor  
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meningitis (wrong in AID): 0-2 months   GBS (agalactiae), Ecoli, listeria  
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meningitis (wrong in AID): 2mo-10yrs   S. PNA, N. meningitides (adolescent yrs only)  
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meningitis (wrong in AID): 10yrs-21yrs   N. meningitides  
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meningitis (wrong in AID): >21yrs   S. PNA  
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Strep pneumo vaccine   given at 2,4,6 months. covers 23 strains (98% of cases). indications include: anyone +65yo, splenectomized (sickle cell), end-organ damage (CF, RF, nephrotic syndrome)  
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strep pyogenes   MCC of all throat infections. 2nd MCC of all skin infxns  
🗑
staphylococcus differentiation   S.aureus-gold pigment, S.epi-white pigment, S.saprophyticus-no pigment.  
🗑
rusty colored sputum   Strep pneumonia (pneumococcus)  
🗑


   

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