Small Class Antibiotics
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| MOA, Aminoglycosides | Inhibit Protein Synthesis
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| Two Aminoglycosides | Gentamycin, Tobramycin
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| Use, aminoglycoside | Gram negatives, in combo with other drugs. Rarely used alone except UTIs.
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| MOA, Macrolides | Inhibit protein synthesis by binding to 50S
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| Name two Macrolides | Clarithromycin, Azithromycin
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| What can a single dose of Azithromycin be used for? | Chlamydia
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| What are Marcolides excellent against? | Atypicals
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| MOA, Ketolides | Inhibit protein synthesis by binding to 50S.
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| Name a Ketolide. | Teltihromycin/Ketek.
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| MOA, Clindamycin | Inhibit protein wall synthesis by binding to 50S.
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| What is a drawback of Clindamycin? | Worst offender of C. Diff Colitis.
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| What is Clindamycin typically used for? | Gram positives, some anaerobes.
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| What is a strength of Clindamycin | Can do community acquired MRSA.
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| What is Metronidazole used for (general and specific)? | Anaerobes and parasites: C. Diff.
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| What are the tetracylcines used against? | Rickettsia and atypical pathogens.
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| Name a tetracylcine. | Doxycycline (Vibramycin)
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| Which antibiotic stains kids teeth? | Tetracyclines
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| What should Septra/Bactrim be used for? | Gram negative urinary pathogens, protozoa, PCP
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| What is Vancomycin used for? | MRSA, very strong against gram positives. No gram negative.
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| Describe Daptomycin. | Like Vanc, but covers more.
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| What should Daptomycin NOT be used for? | Pneumonias/CNS.
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| Name an oxazolidinone? | Linezolid
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| What was oxazolidinone developed to do? | Treat resistant gram positive stuff, MRSA, vanc resistant staph
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| What can the Oxazolidinones cause? | Thrombocytopenia
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