Comprehensive Pharm 8
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| which drugs cause pulmonary fibrosis? | busulfan bleomcyin amiodarone
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| which drugs cause gyneomastia | "Some drugs create awesome knockers" spironolactone digitalis cimetidine alcoholism ketoconazole (estrogen)
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| which drugs cause SLE like syndrome | "it's not HIPP to have lupus" hydralazine inh procainamide phenytoin
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| which drugs --> osteoporosis | CHO corticosteroids heparin
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| which drug --> gingival hyperplasia | phenytoin
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| which drugs --> photosensitivity | Amy played Tetris on her cell phone in the sun amiodarone sulfonamides tetracycline
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| which drugs --> tendonitis and tendon rupture in kids | fluoroquinolones
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| which drug --> gray baby syndrome | chloramphenicol
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| which drugs --> agranulocytosis | colchicine carbamazepine clozapine
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| which drugs --> atropine like side effects | tricyclics
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| which drugs --> cardiac toxicity | Dawn sat on the Docks mending her red, broken heart doxorubicin daunorubicin
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| which drugs --> torsades de pointes | Ia and III aniarrhytmics cisapride
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| which drugs --> focal/massive hepatic necrosis | Hello Val! Have a seat before your liver dies! halothane valproic acid acetaminophen
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| which drug --> fanconi's syndrome | expired tetracycline
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| which drug --> interstitial nephritis | methicillin
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| which drugs --> hemorrhagic cystitis | cyclophosphamide ifosfamide
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| which drug --> hepatitis | INH
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| which drugs --> pseudomembranous colitis | I have to take a CLAMP clindamycin ampicillin
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| which drugs --> nephrotoxicity AND ototoxicity | "if you call, i won't be able to hear you in the bathroom" Cisplatin aminoglycoside loop diuretics
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| which drugs --> seizures | buproprion imipenem clistatin
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| which drugs --> DI | lithium demeclocycline
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| which drugs --> aplastic anemia | chloramphenicol benzene NSAIDS
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| which drug --> coronary vasospasm | cocaine
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| which drugs --> flushing | AIDEN was in the VAN FLUSHING NIACIN and CALCIUM niacin CCB adenosine vancomycin
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| which drug --> hemolysis in G6PD pts | sulfonamides INH aspirin ibuprofen primaquine nitrofurantoin
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| whch drugs --> acute aholestatic hepatitis | macrolides
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| which drugs --> cinchonism | quinidine quinine
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| which drugs --> disulfiram like rxn | metronidazole some cephalosporins procarbazine sulfonylureas
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| which drug --> neurotoxicity/nephrotoxicty | polymyxins
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| uses for cytarabine | AML
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| examples of nitrosureas | "you MUST not let the Nitro go to your head, or you'll do a strip tease- a sin!" carmustine lmoustine semustine streptozacin
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| uses for nitrosureas | brain tumors (incl. GBM)
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| uses of the -platins | Platinum treated BOLTs breast ovarian lung testicular
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| uses for busulfan | "I will bustle to treat my dark CaMeL" CML
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| adverse effects of busulfan | "I will bustle to treat my DARK CaMeL" hyperpigmentation pulmonary fibrosis
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| uses for rubicins | "MS. Hodgkin's will LOB the RED ball" myeloma sarcoma Hodkin's lung ovarian breast
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| uses for dactinomycin | "children ACT out" rhabdomyosarcoma wilm's tumor ewing sarcoma
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| MOA 6MP | blocks do novo purine synth, activated by HGPRTase
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| which 2 drugs work synergistically with each other to prevent DNA replicaion? | 5-FU MTX
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| MOA MTX | blocks DHF reductase, preventing DHF --> THF
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| MOA 5FU | blocks thymidylate synthase (preventing dUMP --> dTMP)
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| which cancer agen has minimal myelosuppression? | bleomycin
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| leucovorin | folinic acid that can reverse some of the myelosuppression associated with MTX (doesn't do anything for 5FU myelosuppression)
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| "rescue agent" for 5FU | thymidine
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| which cancer agent --> macrovesicular fatty change in liver? | MTX
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| cancer agents that alkylate DNA | Busulfan Platins Nitrosureas cyclophosphamide/ifosfamide
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| which alkylating agent requires bioactivation | nitrosureas
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| uses for -phosphamides | non-hodgkin's breast ovarian
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| which drugs intercalate in DNA? | 3D doxorubicin daunorubicin dactinomycin
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| which cancer agents generate free radicals | doxorubicin daunorubicin bleomycin
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