Cell Bio/Histo/Path -6
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| Association for tumor marker: PSA | Screening for Prostatic Carcinoma
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| Association for tumor marker: CEA | -Carcinoembryonic antigen. -In ~70% of colorrectal and pancreatic cancers -Also produced by gastric and breast carcinomas -Very nonspecific
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| Association for tumor marker: alpha-fetoprotein | -Hepatocellular carcinomas -Nonseminomatous germ cell tumors of the testis (eg yolk sac tumor)
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| Association for tumor marker: beta-hCG | -Hydatidiform moles -Choriocarcinomas -Gestational trophoblastic tumors
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| Association for tumor marker: CA-125 | Ovarian malignant epithelial tumors
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| Association for tumor marker: S-100 | -Melanoma -Neural tumors -Astrocytomas
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| Association for tumor marker: Alkaline phosphatase | -Metastases to bone -Obstructive biliary disease -Paget's disease of bone
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| Association for tumor marker: Bombesin | -Neuroblastoma -Lung cancer -Gastric cancer
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| Association for tumor marker: TRAP | -Tartrate-resistance acid phosphatase -Found in hairy cell leukemia
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| What type of cell is found in hairy cell leukemia? | B-cells
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| Association for tumor marker: CA-19-9 | Pancreatic adenocarcinoma
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| Tumor marker for: Prostatic carcinoma | -PSA -Prostatic acid phosphatase
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| Tumor marker for: Colorectal cancer | CEA - Carcinoembryonic antigen -Produced by 70% of colorectal cancers
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| Tumor marker for: Pancreatic cancer | CEA - Carcinoembryonic antigen -Produced by 70% of pancreatic cancers CA-19-9 -Produced in pancreatic adenocarcinoma
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| Tumor marker for: Gastric carcinoma | -CEA - Carcinoembryonic antigen -Bombesin
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| Tumor marker for: Breast carcinoma | CEA - Carcinoembryonic antigen
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| Tumor marker for: Hepatocellular carcinoma | alpha-fetoprotein
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| Tumor marker for: Nonseminomatous germ cell tumors of the testis | alpha-fetoprotein
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| Tumor marker for: Hydatidiform moles | beta-hCG
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| Tumor marker for: Choriocarcinoma | beta-hCG
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| Tumor marker for: Gestational Trophoblastic tumors | beta-hCG
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| Tumor marker for: Malignant ovarian epithelial tumors | CA-125
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| Tumor marker for: Melanoma | S-100
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| Tumor marker for: Neural tumors | General: S-100 Neuroblastoma: Bombesin
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| Tumor marker for: Astrocytomas | S-100
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| Tumor marker for: Metastases to bone | Alkaline phosphatase
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| Tumor marker for: Obstructive biliary disease | Alkaline phosphatase
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| Tumor marker for: Paget's disease of bone | Alkaline phosphatase
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| Tumor marker for: Neuroblastoma | Bombesin
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| Tumor marker for: Lung cancer | Bombesin
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| Tumor marker for: Hairy cell leukemia | TRAP (Tartrate-resistant acid phosphatase)
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| Tumor marker for: Pancreatic adenocarcinoma | CA-19-9
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| Cancer associated with: HTLV-1 | HTLV=Human T-Lymphotropic Virus Adult T-cell leukemia
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| Cancer associated with: HBV | Hepatocellular carcinoma
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| Cancer associated with: HCV | Hepatocellular carcinoma
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| Cancer associated with: EBV | -Burkitt's lymphoma -Nasopharyngeal carcinoma
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| Cancer associated with: HPV | -Cervical carcinoma (with HPV 16,18) -Penile/anal carcinoma
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| Cancer associated with: HHV-8 | HHV-8 = Kaposi's sarcoma-associated herpes virus -Kaposi's sarcoma -body cavity fluid B-cell lymphoma
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| Oncogenic virus associated with: Adult T-cell leukemia | HTLV-1 (HTLV=Human T-Lymphotropic Virus)
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| Oncogenic virus associated with: Hepatocellular carcinoma | -HBV -HCV
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| Oncogenic virus associated with: Burkitt's lymphoma | EBV
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| Oncogenic virus associated with: Nasopharyngeal carcinoma | EBV
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| Oncogenic virus associated with: Cervical carcinoma | HPV 16 and 18
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| Oncogenic virus associated with: Penile carcinoma | HPV
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| Oncogenic virus associated with: Anal carcinoma | HPV
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| Oncogenic virus associated with: Kaposi's sarcoma | HHV-8 (aka Kaposi's sarcoma-associated herpesvirus)
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| Oncogenic virus associated with: body cavity fluid B-cell lymphoma | HHV-8 (Human Herpesvirus 8)
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| Organ affected by: Aflatoxins | Liver (hepatocellular carcinoma)
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| Organ affected by: Vinyl chloride | Liver (angiosarcoma)
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| Organ affected by and effects of: CCl4 | Liver -centrilobular necrosis -fatty change
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| Organ affected by: Nitrosamines | -Esophagus -Stomach
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| Organ affected by: Cigarette smoke | -Larynx -Lung
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| Organ affected by: Asbestos | Lung -Mesothelioma -Bronchogenic carcinoma
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| Organ affected by: Arsenic | Skin (squamous cell carcinoma)
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| Organ affected by: Naphthalene (aniline) dyes | Bladder (transitional cell carcinoma)
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| Organ affected by: Alkylating agents | Blood (leukemia)
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