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Wound Care and Skin Integrity Part 2

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Question
Answer
Serosanguinous or Sanguinous   looks like watery blood - Hemorrhagic - due to capillary damage - Occurs w/severe inflammation/ injury  
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Purulent   Pus Occurs with infection - Thicker, WBCs, dead tissue, & bacteria, Pyogenic – bacteria produced - may be yellow, tan, green,  
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Mucus (mucous)   thick fluid secreted by mucous membranes and glands  
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Phase 4 – Healing   Regeneration and repair - Replacement of lost cells & tissue w/cells of same type  
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What factors may prolong inflammatory phase?   age, autoimmune disease, chronic infections, nutrition deficiencies, immunosuppressants, steroids  
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What might impair granulation or proliferation phase?   dry wound, infection, nutrition (not enough protein or zinc), collagen, anemic (not enough RBCs to get there and heal)  
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Hyperemia   redness due to vasodilation – blanch to see if transient  
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Blanching hyperemia   area blanches and then erythema returns – transient  
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Nonblanching erythema   area does not blanch – deep tissue damage probable  
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In shear, what damage occurs?   deep tissue damage – undermining of dermis  
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In friction, what damage occurs?   epidermis or top layer of skin – sheet burn  
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Skin changes due to age   reduc skin elasticity, decr collagen, slower epithelialization & wound healing, dypodermis decreases in size, less sub Q  
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Primary Intention   Wound closed with sutures, staples, dermabond, Least scarring  
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Secondary Intention   Left open to fill in w/granulation tissue – healing from inside out  
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Why use secondary intention?   To monitor granulation tissue or remove necrotic tissue –adipose tissue takes longer to heal  
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Tertiary Intention or delayed primary closure   wound left open for a period of time & then closed – used w/compartmental syndrome, make sure infection gone before closing  
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Examples of primary intention   surgical incision closed w/suture or staples  
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How does primary intention heal?   by epithelialization – minimal scar formation – by connective tissue deposition  
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How does secondary intention heal?   By granulation tissue formation, wound contraction, and epithelialization  
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Examples of secondary intention   pressure ulcers, burn, severe laceration, surgical wounds w/tissue loss – wound edges not approximated  
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Examples of tertiary intention   contaminated wounds – examining them for inflammation  
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How does tertiary intention heal?   closure of wound delayed until risk of infection, then closed  
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Full thickness wounds heal by   skar formation because deeper structures do not regenerate  
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3 healing stages of partial-thickness wounds   inflammatory response, epithelial proliferation (reproduction) and migration, and reestablishment of epidermis  
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3 healing phases of full-thickness wound repair   inflammatory, proliferative, and remodeling  
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How do steroids affect healing?   suppresses the immune system, masks effects of infection  
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How does infection delay healing?   Uses up available resources, damages tissues  
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Inflammatory Phase   hemostasis, fibrin matrix, neutrophils, then monocytes that transform into macrophages – goal is to stop bleeding and remove debris  
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Proliferative Phase   appearance of new blood vessels, granulation tissue, contraction of wound, epithelialization, collagen  
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What can impair healing during proliferation phase?   age, anemia, hypoproteinemia, and zinc deficiency  
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Remodeling phase   collagen scar formation – takes more than year – scar is remodeled and reorganized into original appearance  
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Hemorrhage occurring after hemostasis indicates?   slipped surgical suture, dislodged clot, erosion of blood vessel by drain, etc.  
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Surgical wound doesn’t show infection till when?   4th or 5th postoperative day  
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Dehiscence   surgical incision has opened - pack w/moist gauze, etc; monitor for signs of infection  
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Increase in serosanguineous drainage from wound could indicate   dehiscence  
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Evisceration   medical emergency – when organ protrudes outside body - dehiscence - cover w/sterile moist gauze over protruding organ & surgery – NPO  
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What can increase incidence of dehiscence and evisceration?Obesity, poor suturing, poor nutrition    
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Fistula   poor wound healing – abnormal passage between 2 organs or between organ and outside of body  
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How do fistulas occur   poor wound healing or complication of disease, trauma, infection, radiation, cancer – tissue layers don’t’ close properly  
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s/sx of internal bleeding?   hematoma, bruising, distention, BP drop, HR incr due to loss of volume, hypotension, tachycardia  
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Contracture   excessive shortening of muscle or scar tissue leads to deformity – when arm or affected parts are immobilized  
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PRESSURE – 3 factors for pressure wounds   Pressure Intensity, Pressure Duration, Tissue Tolerance  
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Impaired Nutrition that affects wounds   not enough protein, zinc, vitamin C  
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Stage I   Superficial, Intact skin, Non-blanchable erythema, Discoloration of darker skin, Warmth, edema (boggy feeling), induration, hardness  
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Stage II or partial thickness   Partial loss of epidermis & dermis, abrasion, blister, Considered infected even if no sx – heals by regeneration  
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Stage III or full thickness   deep crater, Extends into SQ tissue, but not into muscle, necrosis present - slough or eschar – heals by scar formation  
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Stage IV – Full thickness   through SQ into muscle w/extensive destruction, necrosis – may go down to the bone, possible damage to muscle, bone, supporting structures – scar formation  
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How do stage 3 and 4 wounds heal?   through scar formation  
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How does a stage 2 wound heal?   by regeneration  
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Venous stasis ulcers   necrotic crater-like lesion usually found on lower leg at medial malleoli - slow to heal, poor venous return, varicose veins, incompetent valves, DM, arterioscleosis  
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Arterial ulcers   pale, ischemic base, well defined edges found on toes, heels, lateral malleoli  
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Cap refill in arterial ulcer   Greater than 3sec  
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Cap refill in venous ulcer   Less than 3sec  
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Which type of ulcer condition has no edema in the legs, yet has little or no hair there?   arterial  
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Cool skin temperature occurs in which type ulcer?   arterial – venous is warm  
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Contact Dermatitis   caused by exposure to irritant chemical or allergen - poison ivy, metals – nickel  
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Atopic Dermatitis (Eczema)   tendency is inherited causing chronic inflammation from exposure to allergens  
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Urticaria (hives)   type I hypersensitivity reaction (usually caused by something ingested) causing release of histamines – wheals  
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Psoriasis   Unknown origin - Chronic rapid turnover of epidermal cells resulting in thickening and scaling, silvery plaques  
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Cellulitis   infection of dermis & subcutaneous tissue; may be caused by Staph or Strep, insect bite - MRSA, Red, warm, swollen, painful  
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Furuncles   usually cause by Staph which begins in a hair follicle & spreads into surrounding dermis – boil  
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Carbuncle   collection of furuncles that form a large infected mass – if many furuncles together, they are a carbuncle.  
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Acute Necrotizing Fascitis   highly virulent strain of gram positive, group A, beta-hemolytic Strep, history of minor trauma or infection in skin and subQ - Mortality is 30-60%  
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Herpes Zoster (Shingles)   Caused by activation of varicella-zoster virus - affects one cranial nerve or one dermatome innervated by a spinal nerve  
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Cutoff score for onset of pressure ulcer risk with Braden Scale is   18  
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Tinea infections   fungal infection or mycoses  
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Pedis   athlete’s foot  
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Corporis   ringworm of body  
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Capitus   ringworm of head  
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Pediculosis (lice)   contagious parasites that suck blood - head, body, pubic  
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Scabies   contagious, caused by itch mite - Causes burrows, papules, vesicles; very itchy  
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Vitamin A reduces neg effects of   steroids on wound healing  
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Copper is necessary for   collagen fiber linking  
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Best measure of nutritional status is   prealbumin – reflects not only what pt eats but what body has absorbed  
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Basal cell   can be removed. Most common, least likely to metastasize  
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Squamous cell   removal, may require radiation. May metastasize if untreated  
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Malignant Melanoma   Excision & removal of surrounding tissue, Lymph node biopsy, radiation, chemo, immune therapy, A symmetry, B orders irregular, C olor-varied pigmentation brown, black, tan, D iameter > 6mm - pencil eraser  
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Wrinkles – Why?   loss of elasticity  
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Skin tears   lose collagen  
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Senile lentigo or liver spots   areas of discoloration on the skin – tannish - harmless  
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Pruritis   itching due to dry skin  
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Keratosis   overgrowth of horny layer  
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Seborrheic   yellow-brown scales on trunk, face, scalp  
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Macule   frecke, petechia, flat nonpalpable change in skin color – smaller than 1cm  
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Papule   Nevus – palpable, circumscribed, solid elevation in skin – smaller than 1cm  
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Nodule   Wart – elevated solid mass deeper and firmer than papule 1-2 cm  
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Wheal   Hive, mosquito bite – irregularly shaped, elevated areas of superficial localized edema – varies in size  
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Vesicle   Chickenpox, herpes – circumscribed elevation of skin filled w/serous fluid, less than 1cm  
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Pustule   Acne, staphylococcal infection – like a vesicle but filled with pus  
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Ulcer   Venous stasis ulcer – deep loss of skin – extends to dermis – bleeds and scars  
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Atrophy   Arterial insufficiency – thinning of skin w/furrow – skin shiny and translucent  
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Plaque   a patch on the skin or on a mucous surface  
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Fissure   an ulcer or cracklike sore  
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Comedone/comedo   The typically small skin lesion of acne – closed form is a whitehead – papule – open form is a blackhead- rearely inflamed  
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Petichiae   pinpoint purpuric lesions – tiny bruises  
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Purpura   any rash in which blood leaks into skin at multiple sites – associated mostly with coagulation or thrombosis disorders  
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Ischemia (decreased circulation)‏ - disorders causing   PVD, MI, DVT, CVA  
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Causes inflammation without infection   Foreign body, Ischemia‏, Skin, tissue trauma, Temp extremes (Burns, frostbite), Chemicals, radiation, electricity, Allergies, Neoplasms  
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Differentials measure   WBC count incl. neutrophils, lymphs, monos, eosinophils/basophils  
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Neutrophils increase with   bacterial infections or acute trauma – major inflammatory response  
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Which WBCs are the first to respond?   neutrophils – perform phagocytosis  
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Lymps increase with   viral & chronic bacterial infections  
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Monos change into   macrophages in tissues – phagocytosis  
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Monos increase with   protozoan, rickettsial, & TB infections, fungal  
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Eosinphils/Basophils increase with   allergic rxns, not elevated with infections, release chemical that control histamine & serotonin  
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Which WBCs release chemicals that control histamine & serotonin?   Eosinophils/basophils – due to allergic rxn, not infections  
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Total WBCs   4000-10000/mm3  
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Possible critical levels are WBCs   less than 2500 or greater than 30,000 or Absolute neutrophils less than 1000  
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Elevated sedimentation rate Increase w/   generalized inflammatory response  
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C-reactive protein increase w/   inflammation, infection, malignancy  
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