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The following are activities related to the key terms for the chapter.

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Answer
Adverse drug reactions (ADRs)   Unintended side effects from medications such as cough, headache, nausea and so on  
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Anaphylactic reaction   A life-threatening reaction to a drug, insect/jellyfish sting, snake bite or foreign substance requiring immediate medical attention  
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Chemoinformatics   Application of computer technology, statistics and math to study information about the structure, properties and activities of molecules  
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Cumulative effect   Increased effect of a drug that accumulates in the body  
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Dependence   Acquired need for a drug after repeated use; may be psychological with craving and emotional changes or physical with body changes and withdrawal symptoms  
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Dosage   Amount of drug given for a particular therapeutic or desired effect  
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Drug interactions   Response that may occur when more than one drug is taken-The combination may alter the expected response of each individual drug  
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Drug processes   Four biological changes that drugs undergo within the body  
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Hypersensitivity   Allergic or excessive response of the immune system to a drug or chemical  
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Idiosyncratic reaction   Unusual reaction to a drug, other than expected  
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Local effect   Affecting one specific area or part  
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Paradoxical reaction   Opposite effect from that expected  
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Pharmacogenomics   The study of the effects of genetic differences among people and the impact that these differences have on the uptake, effectiveness, toxicity, and metabolism of drugs  
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Placebo effect   Relief from pain as the result of suggestion without active medication  
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Prodrug   A newly developed group of chemicals that exhibit their pharmacological activity after biotransformation  
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Sources of drugs   Five ways that the drugs are obtained being plants, minerals, animals, synthetic and DNA  
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Systemic effect   Affecting the whole body or system  
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Teratogenic effect   Effect of a drug administered to the mother that results in abnormalities in the fetus  
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Therapeutic range   A range of drug levels in the blood that will produce the desired effects without causing serious side effects  
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Tolerance   Decreased response to a drug after repeated dosage; greater amounts of the drug are required for the same effect  
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