WVSOM: Bone
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| 4 cells types found in bone | Ostoecytes, Osteoblast, osteoclast, osteoprogenerators
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| What is primary bone | immature bone. Collagen runs in random directions, low mineral count, and uneven stain
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| What is Secondary bone | mature bone. Deeply acidiphilic, organized, and resembles a "bulls-eye"
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| 2 types of secondary bone | Compact and spongy
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| Describe the composition of spongy bone | made up of spicles and traneculae.
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| What ability does spongy bone have and what gives it this ability | Ability to handle change and/or adjust to external stress. Trabeculae gives it this ability
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| What is the periosteum | noncalcified covering of the outside of the bone
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| What are Sharpeys fibers and where are they found | These hold the periosteum to the bone. Found in the periosteum
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| Is the periosteum vascular | YES
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| What are the two parts of the periosteum | OUter fibrous layer and inner osteogenic layer
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| What is the endosteum | bone's cell lining that covers all of the interior surfaces of the bone
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| What does the endosteum NOT include | osteocytes
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| Describe the structure of an osteon | Haversian system surrounded by matirx in a circumfrential pattern.
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| What interconnects the various osteons in bone | Volkmans canal
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| What makes up the organic matrix called osteoid | ground substance is proteoglycans and glycoproteins. GAG's. Osteonectin and osteocalcin
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| What causes osteoid to be mineralized | deposition of crystals of hydroxapatite
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| Which type of ossification occurs in most bones | Endochondral
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| Which type of ossification uses a cartilage model | Endochondral
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| Which type of ossificatin makes frontal and parietal bones | Intramembranous
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| Which type of ossification uses condensed mesenchyme to differentiate into osteoblast | Intramembranous
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| In which type of ossification does primary immature bone turn to secondary bone by use of osteoclast | Intramembranous
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| Where does bone remodeling take place | at the BMU's (Bone remodeling units)
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| How does bone remodeling work | Osteoblast recieve a signal and then signal to the osteoclast to start working
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| What function does bone remodeling serve | retains shape, size, architecture and repairs minor stress fractures
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| What is osteomalacia | a calcium or vitamin D deficency in adults. Characterized by decalcification of bones
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| What is osteoporosis | decrease in bone mass and quantity associated with a normal ratio of mineral to matirx. Caused by decreased formation and increase reabsorbtion.
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| What can cause osteoporosis | lack of physycial stress, less GH, in women less estrogen
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| Osteochondrodysplasia | extreme bending of long bones
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Created by:
lowryc
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