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Anesthetics

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Generic
MOA
ADR
halothane   1. hyperpolarize nuerons & 2. pre-synaptic: reduces the amount of NT released   Hepatitis, occurs several days after sedation  
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enflurane   1. hyperpolarize nuerons & 2. pre-synaptic: reduces the amount of NT released   Seizures, hypotension  
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isoflurane   1. hyperpolarize nuerons & 2. pre-synaptic: reduces the amount of NT released   Odor, not induction, hypotension  
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desflurane   1. hyperpolarize nuerons & 2. pre-synaptic: reduces the amount of NT released   Strong irritant, not induction, very low partition coefficient  
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sevoflurane   1. hyperpolarize nuerons & 2. pre-synaptic: reduces the amount of NT released   Non-irritating, induction and maintenance  
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nitrous oxide   Antagonizes NMDA and GABAa   Insoluble in blood, adjunct, weak anesthetic, does have analgesic properties  
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thiopental   GABAa Agonist/barbiturates/Increases ClCh opening duration   Suppression of EEG  
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etomidate   GABAa Agonist, hypnosis; no analgesia   Nausea and Vomiting!  
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ketamine   NMDA receptor antagonist. Eyes open, breathe independently   Hypertension!  
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propofol   GABAa Agonist   Respiratory depression! Pt. must be ventilated  
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Created by: piro12
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