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WVSOM: Subject 5 -- Receptor Biology

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Question
Answer
Receptor   a cellular factor that recognizes and binds a specific ligand to induce a response  
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Ligand   a molecule bound by another molecule such as a receptor  
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Intercellular Signaling Molecule   nutrient ligand secreted by one cell to induce a response in another cell  
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Hormone   intercellular signaling molecule that controls metabolism or physiology  
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Growth factor   intercellular signaling molecule that controls cell cycle progression, cellular differentiation, or morphogenesis during development  
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Cytokine   growth factor involved with hematopoiesis  
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Isoreceptors   different receptors bound and activated by the same ligand, often inducing distinct responses in different cells  
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Paracrine   for an intercellular signaling molecule to diffuse over a short distance, usually through interstitial spaces, to induce a response  
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Endocrine   for an intercellular signaling molecule to diffuse through the blood  
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Hydrophobic Ligands   Steroids (cholesterol derivatives) Fatty acid derivatives (prostoglandins, retinoic acid)  
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Hydrophilic Ligands   Amino acid derivatives (catecholamines-tyrosine, histamine-histidine, serotonin-tryptophan) Peptides and proteins (insulin, glucagon, FSH, TGFβ, etc.) Nucleotides (cAMP) No carbohydrates - this is the only major class of biochemicals not used as recept  
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Transport proteins   action potential initiation & propagation  
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Serine/threonine Kinases   Tissue Differentiation Tissue Patterning Immunosuppression Cell Cycle progression  
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Seven Receptor Transmembrane   blood glucose levels metabolism menstrual cycle inflamation glycogenolysis  
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Tyrosine Kinases   blood glucose levels metabolism cell proliferation cell cycle progression differentiation apoptosis. glycogen synthesis  
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TGF-b   Tissue Differentiation Tissue Patterning Immunosuppression Cell Cycle progression  
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Ras   TYROSINE KINASES metabolism glycogen synthesis blood glucose levels cell cycle progression apoptosis. differentiation  
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Phosphoinositide   TYROSINE KINASE cell proliferation  
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cAMP   SEVEN TRANSMEMBRANE RECEPTOR blood glucose levels metabolism glycogenolysis menstrual cycle inflamation  
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synaptic ligand-gated ion channels   TRANSPORT PROTEINS action propagation initiation & potential  
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Created by: tjamrose
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