Includes Brand Name, Generic Name, Therapeutic Class, and Mechanism of Action
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| Lortab | hydrocodone and APAP/ Narcotic Analgesic | hydrocodone: opiod receptor agonist
acetaminophen: analgesic effect unknown, affects hypothalamic heat regulating center (antipyretic)
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| Synthroid | levothyroxine/ thyroid hormone | levothyroxine (T4) replacement
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| Xanax | alprazolam/ antianxiety | benzodiazepine: binds to receptors in the central nervous system (CNS)
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| Micro-K, K-Dur, Klor-Con | potassium chloride/ potassium supplement | potassium supplement
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| Glucophage | metformin hydrochloride/ antidiabetic | main effect believed to be inhibition of hepatic gluconeogenesis (multiple MOAs suspected)
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| Zestril, Prinivil | lisinopril/ ace inhibitor | ACE-I (angiotensin converting enzyme inhibitor)
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| Ultram | tramadol/ analgesic | binds to opioid receptor, and also inhibits reuptake of norepinephrine(NE) and seratonin (5-HT)
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| Lasix | furosemide/ diuretic | "loop diuretic": blocks sodium and chloride reabsorption from kidney tubules
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| Lipitor | atorvastatin/ antihyperlipidemic | inhibits 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) and increases hepatic low-density lipoprotein (LDL) receptors
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| Percocet | oxycodone and APAP/ narcotic analgesic | oxycodone: opioid receptor agonist
acetaminophen: analgesic effect unknown; affects hypothalamic heat regulating center (antipyretic)
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| Tenormin | atenolol/ beta blocker | beta-1 receptor antagonist
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| Toprol XL | metoprolol succinate/ beta blocker | beta-1 selective receptor antagonist
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| Lopressor | metoprolol tartrate/ beta blocker | beta-1 receptor antagonist
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| HydroDiuril | hydrochlorothiazide/ diuretic | Diuretic effect: blocks reabsorption of sodium and chloride from renal tubules
Antihypertensive effect unknown
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| Coumadin | warfarin/ anticoagulant | inhibits vitamin K dependent clotting factors
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| Norvasc | amlodipine/ calcium channel blocker | dihydropyridine calcium channel blocker
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| Amoxil | amoxicillin/ antibiotic | beta lactam antibiotic; inhibits cell wall synthesis of mucopeptide
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| OxyContin | oxycodone/ narcotic analgesic | opioid receptor agonist
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| Zithromax | azithromycin/ antibiotic | macrolide antibiotic; inhibits microbial protein synthesis
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| Darvocet | propoxyphene and APAP/ narcotic analgesic | propoxyphene: binds to opioid receptor (like codeine, hydrocodone)
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| Zoloft | sertraline/ antidepressant | selective seratonin reuptake inhibitor (SSRI)
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| Zantac | ranitidine/ H2 antihistamine | Histamine-2 receptor antagonist
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| Zocor | simvastatin/ antihyperlipidemic | inhibits HMG-CoA and increases hepatic LDL receptors
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| Lexapro | escitalopram/ antidepressant | SSRI
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| Nexium | esomeprazole/ antisecretory | proton pump inhibitor (PPI)
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| Seroquel | quetiapine/ antipsychotic | Serotonin(5HT), dopamine(DA), histamine and alpha receptor blockers
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| Proventil | albuterol/ antiasthmatic/bronchodilator | beta-2 selective receptor agonist
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| Singulair | montelukast/ antiasthmatic | Leukotriene receptor antagonist
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| Plavix | clopidogrel/ platelet inhibitor | adenosine diphosphate(ADP) receptor antagonist
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| Deltasone | prednisone/ steroid/anti-inflammatory | inhibits phospholipase, prostaglandins, and leukotrienes (mediators of inflammation)
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| Effexor | venlafaxine/ antidepressant | potentiates activity of serotonin, norepinephrine, and dopamine
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| Elavil | amitriptyline/ antidepressant | increases 5HT and NE levels (prevents reuptake)
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| Ativan | lorazepam/ antianxiety | benzodiazepine: binds to receptors in the CNS
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| Neurontin | gabapentin/ antiepileptic | MOA unknown
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| Glucotrol | glipizide/ antidiabetic | Sulfonylurea: increases pancreatic insulin secretion
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| Naprosyn | naproxen/ NSAID | inhibits prostaglandin synthesis
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| Wellbutrin | bupropion/ antidepressant | inhibits DA and NE uptake
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| Desyrel | trazodone/ antidepressant | MOA unknown; believed to increase serotonin levels
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| Prilosec | omeprazole/ antisecretory | PPI
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| Dyazide | triamterene and HCTZ/ diuretic | Triamterene: inhibits the reabsorption of sodium in exchange for potassium and hydrogen ions in the renal tubule
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| Flexeril | cyclobenzaprine/ muscle relaxant | reduces motor activity in the brainstem
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| Duragesic | fentanyl transdermal system/ narcotic analgesic | opioid receptor agonist
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| Prozac | fluoxetine/ antidepressant | SSRI
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| Fosamax | alendronate/ osteoporosis agent | osteoclast inhibitor
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| Vasotec | enalapil/ ace inhibitor | ACE-I
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| Prevacid | lansoprazole/ antisecretory | PPI
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| Lantus | insulin glargine/ antidiabetic | binds to insulin receptor (24 hour insulin)
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| Prempro | conjugated estrogens and medroxyprogesterone acetate/ estrogen/progestin combination hormone | estrogen and progesterone receptor agonists, respectively
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| Lanoxin | digoxin/ cardiovascular | inhibits sodium-potassium ATPase
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| Valium | diazepam/ antianxiety | Benzodiazepine(BZD): same as Xanax
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| Keflex | cephalexin/ antibiotic | cephalosporin: inhibits cell wall synthesis
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| Paxil | paroxetine/ anti-depressant | SSRI
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| Reglan | metoclopramide/ anti-emetic | anti-emetic: inhibits DA receptors, which increases vomiting threshold
GI motility stimulant: cholinergic activity becomes greater than that of dopamine, which increases smooth muscle response to ACh(Acetylcholine) and causes GI motility
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| Cardizem | diltiazem/ calcium channel blocker | Non-DHP calcium channel blocker
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| Ambien | zolpidem/ hyonotic | agonist of benzodiazepine gamma-aminobutyric acid (GABA-A) subunit
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| Celexa | citalopram/ antidepressant | SSRI
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| Advair | fluticasone & salmeterol/ antiasthmatic | fluticasone: inhibits phospholipase, prostaglandins, and leukotrienes
salmeterol: beta-2 receptor agonist
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| Zestoretic, Prinzide | lisinopril & hydrochlorothiazide/ antihypertensive | lisinopril: ACE-I HCTZ: loop diuretic
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| Vytorin | simvastatin & ezetimibe/ antihyperlipidemic | simvastatin: HMG-CoA reductase inhibitor ezetimibe: cholesterol absorption inhibitor
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| Zyrtec | cetirizine/ antihistamine | H-1 receptor antagonist
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| Fioricet | APAP, butalbital & caffeine/ analgesic | butalbital: causes sensory depression by inhibiting conduction in areas of the brain caffeine: stimulates CNS by increasing levels of cAMP
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| Diflucan | fluconazole/ antifungal | inhibits fungal steroid production
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| Ortho-Tricyclen | norgestimate & ethinyl estradiol/ oral contraceptive | norgestimate: progesterone receptor agonist EE: estrogen receptor agonist
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| Depakote | divalproex/ antiepileptic & antipsychotic | MOA unknown (may increase brain GABA levels)
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| Adderall | amphetamine & dextroamphetamine/ CNS stimulant | sympathetic amine with effects similar to epinephrine
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| Celebrex | celecoxib/ NSAID | Cyclo-oxygenase 2 inhibitor
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| Diovan | valsartan/ AT2 antagonist | angiotension-2 receptor blocker
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| Lotrel | amlodipine & benazepril/ antihypertensive | amlodipine: DHP calcium channel blocker benazepril: ACE-I
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| Allegra | fexofenadine/ antihistamine | H-1 receptor antagonist and inhibits histamine release
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| Klonopin | clonazepam/ antiepileptic | benzodiazepine: believed to enhance GABA activity
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| Augmentin | amoxicillin & clavulanate/ antibiotic | clavulanate(clavulanic acid): beta-lactamase inhibitor, which increases the antibacterial activity of beta-lactam antibiotics
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| Cymbalta | duloxetine/ antidepressant | SSNRI: selective seratonin and norepinephrine reuptake inhibitor
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| Risperdal | risperidone/ antipsychotic | MOA unknown (affects serotonin and DA receptors
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| Levaquin | levofloxacin/ antibiotic | Quinolone antibiotic: inhibits bacterial DNA synthesis
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| Aldactone | spironolactone/ diuretic | aldosterone antagonist at the distal convoluted renal tubule
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| Lyrica | pregabalin/ anticonvulsant | MOA unknown (may bind to alpha-2 delta receptors in the CNS
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| Zyloprim | allopurinol/ agent for gout | xanthine oxidase inhibitor, which decreases uric acid production
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| Protonix | pantoprazole/ antisecretory | PPI
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| Actos | pioglitazone/ antidiabetic | peroxisome proliferator-activated receptor (PPAR) gamma agonist
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| Dilantin Kapseals | extended phenytoin/ antiepileptic | enhances neuronal sodium efflux
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| Kenalog | triamcinolone acetonide topical/ corticosteroid | inhibits phospholipase, prostaglandins, and leukotrienes
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| Motrin | ibuprofen/ NSAID | inhibits prostaglandin synthesis
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| Altace | ramipril/ ACE-I | ACE-I
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| Coreg | carvedilol/ beta blocker | non-selective beta blocker (blocks B-1, B-2, and alpha-1 receptors)
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| Verelan | verapamil/ calcium channel blocker | non-DHP calcium channel blocker
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| Estrace | estradiol/ estrogen | estrogen receptor agonist
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| Catapres | clonidine/ antihypertensive | alpha-2 receptor agonist
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| Soma | carisoprodol/ muscle relaxant | MOA unknown (works centrally to produce muscle relaxation)
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| Zetia | ezetimibe/ antihyperlipidemic | cholesterol absorption inhibitor
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| Amaryl | glimepiride/ antidiabetic | sulfonylurea: increases pancreatic insulin release
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| Flomax | tamsulosin/ treats BPH | alpha-1 receptor antagonist
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| Diovan-HCT | valsartan & hydrocholorothiazide/ AT2 antagonist | valsartan: angiotensin receptor-2 blocker
HCTZ: diuretic
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| Humalog | insulin lispro/ antidiabetic | binds to insulin receptor (ultra short-acting insulin)
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| Flonase | fluticasone/ nasal decongestant | inhibits phospholipase, prostaglandins, and leukotrienes
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| Tylenol w/ Codeine | APAP & codeine phosphate/ analgesic | same as hydocodone
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| Aricept | donepezil/ antipsychotic | acetylcholinesterase inhibitor (Ach-I)
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| Mevacor | lovastatin/ antihyperlipidemic | HMG-CoA reductase inhibitor
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| Accupril | quinapril/ ACE-I | ACE-I
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| Miralax | polyethylene glycol (PEG) 3350/ laxative | osmotic agent (causes water to be retained in the stool)
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| MS Contin | morphine sulfate/ analgesic | opioid receptor agonist
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| Lotensin | benazepril/ ACE-I | ACE-I
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| phenobarbital | phenobarbital/ antiepileptic | produces sensory cortex depression
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| Cleocin | clindamycin/ antibiotic | suppresses bacterial protein synthesis
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| Theo-Dur | theophylline/ antiasthmatic, bronchodilator | couses endogenous epinephrine release, inhibits histamine release, and may prevent release of SRS-A (slow-reacting substance of anaphylaxis)
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| Pravachol | pravastatin/ antihyperlipidemic | HMG-CoA enzyme reductase inhibitor
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| Lamictal | lamotrigine/ antiepileptic | MOA unknown. may block neuronal sodium channels
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| Voltaren | diclofenac/ NSAID | inhibits prostaglandin synthesis
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| Spiriva | tiotropium/ antiasthmatic, bronchodilator | anticholinergic, causing airway smooth muscle relaxation
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| Cogentin | benztropine/ antiparkinson agent | blocks cholinergic histamine receptors
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| Mobic | meloxicam/ NSAID | cyclo-oxygenase inhibitor (COX-2 inhibitor)
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| Strattera | atomoxetine/ treatment for ADHD | selective NE reuptake inhibitor
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| Yasmin | drospirenone & EE/ oral contraceptive | drospirenone: progesterone receptor agonist EE: estrogen receptor agonist
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| Ortho-Novum 7/7/7 | norethindrone and EE/ oral contraceptive | norethindrone: PRA EE: ERA
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| Hytrin | terazosin/ antihypertensive, BPH treatment | alpha-1 receptor agonist
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| Avapro | irbesartan/ ARB | angiotensin- 1 receptor blocker
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| Veetids | penicillin V potassium/ antibiotic | inhibits cell wall mucopeptide synthesis
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| Lopid | gemfibrozil/ antihyperlipidemic | increases activity of lipprotein lipase
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| Skelaxin | metaxalone/ muscle relaxant | MOA unknown
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| Inderal | propranolol/ beta blocker | beta blocker
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| Zovirax | acyclovir/ antiviral | inhibits viral DNA replication
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| Benicar-HCT | olmesartan and HCTZ/ antihypertensive | ARB and diuretic
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| Adipex-P | phentermine/ obesity management | sympathomimetic amine, CNS stimulation and elevation of blood pressure
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| Bactroban | mupirocin/ topical antibacterial | inhibits bacterial protein synthesis
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| Aciphex | rabeprazole/ PPI | PPI
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| Pepcid | famotidine/ H2 antihistamine | H-2 receptor blocker
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| Imuran | azathioprine/ immunosuppressant | interferes with viral RNA and DNA precursors
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| Bentyl | dicyclomine/ anticholinergic | anticholinergic causing smooth muscle relaxation
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| Clozaril | clozapine/ antipsychotic | antagonist at anticholinergic, histaminergic, seratonergic, and adrenergic receptors. also blocks certain dopamine receptors
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| Biaxin | clarithromycin/ antibiotic | inhibits bacterial protein synthesis
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| methadone | methadone/ analgesic | opioid receptor agonist
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| Provera | medroxyprogesterone/ progestin hormone | progesterone receptor agonist
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| Requip | ropinirole/ antiparkinson agent | dopamine agonist
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| Prempro | conjugated estrogens and progesterone/ estrogen, progestin combo | estrogen and progesterone receptor agonists
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| Lithobid | lithium carbonate/ antipsychotic | MOA unknown, may antagonize release of NE and DA or increase their reuptake
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| BuSpar | buspirone/ antianxiety | dopamine and serotonin agonist
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| Omnicef | cefdinir/ antibiotic | inhibits bacterial cell wall synthesis
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| Lunesta | eszopiclone/ hypnotic | agonis of GABA receptors in the CNS
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| Relafen | nabumetone/ NSAID | inhibits prostaglandin synthesis
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| Allegra-D | fexofenadine & pseudophed/ antiallergy | fexofenadine: H1 receptor antagonist and inhibits histamine release
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| Niaspan | niacin/ antihyperlipidemic | enhances lipoprotein lipase activity
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| Bumex | bumetanide/ diuretic | loop diuretic: blocks sodium and chloride reabsorption from kidney tubules
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| Demadex | torsemide/ diuretic | loop diuretic: blocks sodium and chloride reabsorption from kidney tubules
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| Lotrisone | clotrimazole & betamethasone/ topical antifungal | increases permeability of fungal cell wall
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| Lomotil | diphenoxylate & atropine/ antidiarrheal | diphenoxylate: binds to intestinal opiate receptors, decreases GI mobility atropine: added intentionally to prevent abuse or overdosage of the diphenoxylate (also an antimuscarinic which decreases GI motility)
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| lactulose | lactulose/ laxative | digested into lactic acid, which increases osmotic pressure. (causes water to be absorbed into the stool, and loosens stool)
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| Monopril | fosinopril/ ACE-I | ACE-I
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| Guaifenex PSE | guaifenesin & pseudoephedrine/ decongestant, expectorant | guaifenesin: thins bronchial secretions, lubricating irritated respiratory tract
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| Flovent | fluticasone/ antiasthmatic,steroid | inhibits phospholipase, prostaglandins, and leukotrienes (mediators of inflammation)
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| Imitrex | sumatriptan/ antimigrainous agent | 5HT-1 receptor agonist
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| Antivert | meclizine/ antivertigo agent | antihistamine
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| Cozaar | losartan/ angiotensin II Blocker | ARB
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| Ditropan | oxybutynin/ anticholinergic | causes the smooth muscle of the bladder to relax
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| Detrol | tolteridine/ antimuscarinic | Muscarinic receptor antagonist
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| Combivent | ipratropium & albuterol/ antiasthmatic, bronchodilator | ipratropium: anticholinergic, which dilates bronchioles albuterol: beta-2 selective receptor agonist
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| Tricor | fenofibrate/ antihyperlipidemic | PPAR alpha agonist
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| Zyprexa | olanzapine/ anti-psychotic | MOA unknown: believed to antagonize effects of DA and 5HT
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| Crestor | rosuvastatin/ antihyperlipidemic | statin: HMG-CoA reductase inhibitor
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| Remeron | mirtazapine/ antidepressant | Increases central NE and 5HT activity
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| Procardia | nifedipine/ CCB | Dihydropyridine CCB
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| Imdur | isosorbide mononitrate/ antianginal | organic nitrate, which causes arterial and venous dilation
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| Topamax | topiramate/ antiepileptic | MOA unknown: believed to potentiate effects of GABA
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| Actonel | risedronate/ osteoporosis agent | Inhibits osteoclasts
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| Atrovent | Ipratropium/ antiasthmatic, antiallergy | anticholinergic, which dilates bronchioles
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| Medrol | methylprednisone/ anti-inflammatory, steroid | Inhibits phospholipase, prostaglandins, and leukotrienes (mediators of inflammation)
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| Tessalon Perles | benzonatate/ antitussive | suppresses cough by anesthetizing the stretch receptors in the respiratory tract
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| Ultracet | tramadol & acetaminophen/ analgesic | tramadol: binds to opioid receptor, and also inhibits reuptake of NE and 5HT
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| Sinequan | doxepin/ antidepressant | inhibits neuronal NE and 5HT reuptake
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| Ritalin | methylphenidate/ CNS stimulant | sympathetic amine with effects similar to epinephrine
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| Avandia | rosiglitazone/ antidiabetic | PPAR gamma agonist
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| Cipro | ciprofloxacin/ antibiotic | Quinolone antibiotic: inhibits bacterial DNA synthesis
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| Bactrim | sulfamethoxazole & trimethoprim/ antibiotic | sulfamethoxazole: inhibits production of dihydrofolic acid, which kills bacteria trimethoprim: interferes with the production of folic acid (bacteriocidal)
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| folic acid | folic acid/ vitamin | dietary supplement
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| Phenergan | promethazine/ antihistamine, antitussive | H1 receptor blocker
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| Macrobid(Macrodantin) | nitrofurantoin/ antibacterial | inhibits bacterial carbohydrate metabolism
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| Pyridium | phenazopyridine/ urinary tract analgesic | MOA unknown: exerts topical analgesic effect in the urinary tract
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| Hyzaar | losartan &HCTZ/ antihypertensive | losartan: ARB HCTZ: diabetic
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| Dilacor | diltiazem/ CCB | Non-dihydropyridine CCB
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| Vibramycin | doxycycline/ antibiotic | Inhibits bacterial protein synthesis
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| Capoten | Captopril/ ACE-I | ACE-I
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| Tegretol | carbamazepine/ antiepileptic | decreases responsiveness at neuronal synapses
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| Concerta | methylphenidate/ CNS stimulant | sympathetic amine with effects similar to epinephrine
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| Trileptal | oxcarbazepine/ antiepileptic | Inhibits neuronal sodium channel efflux
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| Evista | raloxifene/ osteoporosis agent | selective estrogen receptor modifier(SERM). Only binds to certain estrogen receptors
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| Glucovance | glyburide & metformin/ antidiabetic | sulfonylurea: increases pancreatic secretion of insulin metformin: inhibition of hepatic gluconeogenesis
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| Namenda | memantine/ antipsychotic | NMDA receptor antagonist
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| Cardura | doxazosin/ alpha blocker | Alpha-1 receptor blocker
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| Novolog | insulin aspart/ antidiabetic | binds to insulin receptor
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| Flagyl | metronidazole/ antibacterial, antiprotozoal | causes bacterial DNA strand to break
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| Nasonex | mometasone/ antiallergy | inhibits phospholipase, prostaglandins, and leukotrienes (mediators of inflammation)
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| Restoril | temazepam/ hypnotic | benzodiazepine
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| Micronase | glyburide/ antidiabetic | sulfonylurea: increases pancreatic production
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| Xoponex | levalbuterol/ antiasthmatic, bronchodilator | beta-2 selective receptor agonist
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| Xalatan | latanoprost/ glaucoma agent | prostaglandin analogue
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| Benicar | olmesartan/ ARB | ARB
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| Alesse | levonorgestrel & EE/ oral contraceptive | levonorgestrel: binds to progesterone receptors EE: binds to estrogen receptors
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| Abilify | aripiprazole/ antipsychotic | partial DA and 5HT receptor agonist
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| Duoneb | ipratropium & albuterol/ antiasthmatic | see above for both
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| Armour Thyroid | dessicated thyroid | thyroid hormone replacement
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| nystatin | nystatin oral/ antifungal | Increases fungal cell membane permeability
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| Ziac | bisoprolol & HCTZ | bisoprolol: beta-1 receptor blocker HCTZ: diuretic
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Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
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Created by:
ashley3185
Popular Pharmacology sets