System based disorders II
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
|
|
||||
|---|---|---|---|---|---|
| Cystic Fibrosis | respiratory, exocrine pancreas, intestesting, vas deferens, hepatobiliary and sweat glands
🗑
|
||||
| Cystic fibrosis | 15-20% neonates meconium ileus
>95% males infertile
🗑
|
||||
| Cystic fibrosis | dx: sweat Cl>60 mEq/L OR CFTR disease causing mutations
🗑
|
||||
| Cystic fibrosis | deltaF508 (0.7 of ~1500 alleles)
🗑
|
||||
| Cystic fibrosis | antibiotics, bronchodilators, mucolytic (pulmonzyme, mucomyst), chest PT; avoid smoking, resp viruses and dehydration
🗑
|
||||
| Cystic fibrosis | mutation specific therapy (G551D) using Ivacaftor/Kalydeco
🗑
|
||||
| Heritable Pulmonary Arterial Hypertension (HPAH) | dyspnea 60%, fatigue 19%, chest pain 7%, edema 3%; PA pressure <25 mmHg (rest)/ >30 (exercise) and other causes exclueded;
increased PA pressure causes right heart failure and death within 3 yrs of dx
🗑
|
||||
| Heritable Pulmonary Arterial Hypertension (HPAH) | ~6% of cases familial: AD w/ 10% pen, variable age onset and ?anticipation;
2.4 females/males;
BMPR2 and ACVRL1, BMPR1B, CAV1,, ENG and SMAD8 rare
🗑
|
||||
| Heritable Pulmonary Arterial Hypertenstion | treatment; sc/iv treprostinil,; po Bosentant, sildenafil; neb Iloprost and IV epoprostenol
🗑
|
||||
| Idiopathic Pulmonary Fibrosis (IPF) | Bibasilar reticular anomalies/nodules on high res CT, abnl lung func (VC), usually 50-70 yrs; +/- lung Ca; 30-50% 5 yr survival
🗑
|
||||
| Idiopathic Pulmonary Fibrosis (IPF) | TERT and TERC (short telomeres) or SFTPC in 8-15% multiplex or 3% simplex; all AD reduced penetrance;
🗑
|
||||
| Pulmonary Fibrosis | occurs in Hermansky Pudlak (AR),
Dyskeratosis Congenita (AD, AR, XL)
🗑
|
||||
| Idiopathic Pulmonary Fibrosis | treatment: supp O2, lung transplant, no smoking
🗑
|
||||
| Adenosine Deaminase Def | SCID with FTT, opportunistic infections, marked lymphocytopenia, absent humoral and cellular, usually Dx <6/12
🗑
|
||||
| Adenosine Deaminase Def | <1% ADA activity (purine metabolism) or 2 known ADA causing muts (AR)
🗑
|
||||
| Adenosine Deaminase Def | antibiotic, antifungual, IV immunoglobulin (IVIg), Pneumocystis prophylaxis, bone marrow/stem cell transplant; PED ADA ERT
🗑
|
||||
| Common Variable Immune Def (CVID) | humoral immune def after 24/12 (often young adults), sinopulmonary (Strep, H flu, Kleb pn), meningitis after bacterial infections, chronic diarrhea, malabsorption, +/- lymphoid hyperplasia, autoimmune, lymphomas
🗑
|
||||
| Common Variable Immune Def (CVID) | IgG < 100 mg/dL to low, poor response to Pneumovax
🗑
|
||||
| Common Variable Immune Def (CVID) | loss RAC1, CD19, BAFFER protein; TNFRSF13B (TAC1)10-15%, ICOS (<1%), muts (AD, AR)
🗑
|
||||
| Common Variable Immune Def (CVID) | rx: immune globulin (IVIg), antibiotics, monitor lymphoma, thyroid function
🗑
|
||||
| AD Hyper IgE syndrome | boils, cysts forming pneumonia and very high IgE; characteristic face, Chiari malform, +/- eczema, candiasis, osteopenia, fractures, scoliosis, arterial tortuosity and aneurysms
🗑
|
||||
| AD Hyper IgE syndrome | IgE >2000 IU/mL (~15X)
STAT3 gene (AD)
🗑
|
||||
| AD Hyper IgE syndrome | rx: antibiotics to prevent Staph absecess/pn
🗑
|
||||
| X linked hyper IgM syndrome | 50% onset by 1 yr, >90% by 4yr; recurrent respiratory bacterial, recurrent diarrhea w/ FTT; neutro & thrombopenia, anemia; 10-15% CNS infections; liver, GI, pancreatic tumors; lymphoma (Hodgkins) and EBV
🗑
|
||||
| X linked hyper IgM syndrome | CD40LG (aka TNFSF5/CD154) muts in 95% of affected males (XL)
🗑
|
||||
| X linked hyper IgM syndrome | allogenic hematopoietic cell transplantation, recombinant granulocyte stim factor (G-CSF) for neutopenia, antibiotics
🗑
|
||||
| IPEX syndrome | Immune dysregulation, Polyendocrinopathy, Enteropathy; watery diarrhea, eczema, diabetes, autoimmune thyroid, anemia, low polys and plts, tubular neuropathy
🗑
|
||||
| IPEX syndrome | FOXP3 muts in ~25% affected males (XL)
🗑
|
||||
| IPEX syndrome | rx: immunosuppression, steriods, granulocyte stim factor, bone marrow transplant
🗑
|
||||
| XL SCID | severe combined cellular and humoral immunodef, present 1-3/12 w FTT, oral/diaper candidiasis, absent tonsils and lymph nodes, recurrent and presistent infections
🗑
|
||||
| XL SCID | NBS in 10 states, IL2RG muts found in >99% of affected males (XL)
🗑
|
||||
| XL SCID | rx: antibiotics (esp pneumocystis, IVIg, bone marrow transplant ASAP, gene therapy?
🗑
|
||||
| AR SCID | SCID presents in 1st yr, recurrent bacterial, viral, and opportunistic infections, diarrhea, oral moniliasis, FTT, Pneumocystis, usually die by 2 yrs unless stem cell transplant
🗑
|
||||
| AR SCID | due to abnl T cell receptor signaling; low CD3,4,8 T cells; ZAP70 muts (AR)
🗑
|
||||
| AR SCID | IVIg, antibacterial,-fungal, -protozoal, allogenic HSCT within 3/12; avoid live viral vaccines
🗑
|
||||
| GATA1 related XL cytopenia | thrombocytopenia +/- anemia w 1 or more of the following: plt dysfx, mild beta thal, neutropenia and congen erythropoietic porphyris in males
🗑
|
||||
| GATA1 related XL cytopenia | rx: plt or rbc transfusions, avoid ASA, NSAIDs
🗑
|
||||
| Hemophilia A | prolonged oozing after trauma, tooth extractions or surgery, age at dx relates to F8 activity, sever joint/deep muscle bleeds <2 yrs, 10% carriers bleed
🗑
|
||||
| Hemophilia A | Low F8 clotting activity with nl von Willebrand factor level; F8 muts in 98% of affected males (XL), IVS 22 inversion in 48% severe cases and dels/dups in 6%
🗑
|
||||
| Hemophilia A | hemophilia center, IV F8, DDAVP, avoid ASA, IM injections, impact sports and activities, and always rx before circumcision
🗑
|
||||
| Hemophilia B | prolonged oozing after trauma, tooth extractions or surgery, age at dx relates to F9 activity, severe joint/deep muscle bleeds <2yrs, 10% carriers bleed
🗑
|
||||
| Hemophilia B | low F9 clotting activity; F9 mut in 100% of affected males (XL), dels/dups 3%
🗑
|
||||
| Hemophilia B | rx; hemophilia center, IV F9, avoid ASA, IM injections, impact sports and activities; always rx before circumcision
🗑
|
||||
| Sickle Cell Disease | intermittent vaso-oclusive events and hemolytic anemia, dactylitis, splenic infarction and asplenia, cholelithiasis, PAH, leg ulcers
🗑
|
||||
| Sickle cell Disease | HBB muts B(s) Glu6Val, B(c), B(punjab), B(arab) - all AR; SS and SC <3.6% and Sb(thal) >3.6% Hb A2
🗑
|
||||
| Sickle Cell Disease | rx: hydration, transfusion, penicillin, hydroxyurea, rx PAH phosphodiesterase inhibs/nitric oxide
🗑
|
||||
| Alpha Thalessemia | significant Hb Bart hydrops fetalis (Hb Bard Syn) and HbH disease w 90% vs 5% Hb Bart
🗑
|
||||
| Alpha Thalessemia | Hb Bart syn, HbH, alpha thal trait, silent carrier and nl have deletion of 4,3,2,1,1 alpha globin genes; dels 90% and point 10% of mut, alpha thal moderates SS
🗑
|
||||
| Alpha Thalessemia | rx: Hb Bart syn fatal, HbH transfuse prn; avoid excess FE rx and sulphonamides in HbH
🗑
|
||||
| Hb Bart syndrome | 4 null alpha genes
🗑
|
||||
| HbH | 3 null alpha genes
🗑
|
||||
| alpha thal trait | 2 null alpha genes (in cis or trans)
🗑
|
||||
| silent carrier | 1 null alpha gene
🗑
|
||||
| Beta Thalessemia | reduced beta globin causes microcytic hypochromic anemia and dec HbA; Bthal major > severe anemia and hepatosplenomegaly <2 yrs, marrow expansion
🗑
|
||||
| Beta Thalessemia | RBC indices, dec Hb A2 and inc Hb F >12 months; nucleated RBCs
🗑
|
||||
| Beta Thalessemia | rx; regular transfusion, Fe chelation, bone marrow transplant, splenectomy?; monitor endo function; avoid EtOH & iron meds
🗑
|
||||
| Thiamine Responsive Megaloblastic Anemia | triad of megaloblastic anemia, SNHL and DM; +/- optic atrophy, CHD, arrythmias, strokes
🗑
|
||||
| Thiamine Responsive Megaloblastic Anemia | SLC19A2 muts in 100% (AR)
🗑
|
||||
| Thiamine Responsive Megaloblastic Anemia | rx: anemia corrected by high dose Thiamine (B1), RBC remain macrocytic and SNHL irreversible
🗑
|
||||
| XL Adrenal Hypoplasia Congenita (AHC) | acute adrenal insufficiency by 3 wks in ~60%; vomiting, hypoglycemia and salt wasting with hyper kalemia; +/- cryptochidism
🗑
|
||||
| XL Adrenal Hypoplasia Congenita (AHC) | NROB1 (DAX1) dels in 100% with glycerol kinase def +/- DMD; but point muts in nearly all isolated AHC
🗑
|
||||
| XL Adrenal Hypoplasia Congenita (AHC) | rx: IV glucose, NaCl; glucocorticoids, mineralocorticoids and NaCl
🗑
|
||||
| Antley Bixler (cyto p450 oxidooreductase def) | steroidogenic defect ranging from cortisol deficiency to Antly Bixler syndrome with ambiguous genitalia, craniosynostosis, choanal atresia,radiohumeral synostosis
🗑
|
||||
| Antley Bixler (cyto p450 oxidooreductase def) | sterol/steriod abnormalities, POR muts (AR)
🗑
|
||||
| Antley Bixler (cyto p450 oxidooreductase def) | rx: tracheostomy, cortisol, surgery for craniosynostosis and hypospadias
🗑
|
||||
| Congenital Adrenal Hyperplasia | >90% CYP21OHD, impaired cortisol synthesis by adrenal cortex, simple virilizing (25%) and salt wasting (low cortisol and inadequate aldosterone) (75%), NBS of neonates lowers risk for initial fatal salt wasting crisis
🗑
|
||||
| Congenital Adrenal Hyperplasia | CYP21A2 panel of 9 seq or del/dups detect 80-98% (AR)
🗑
|
||||
| Congenital Adrenal Hyperplasia | rx: glucocorticoid (increase w stress), salt wasting add mineralocorticoid and NaCl
🗑
|
||||
| Congenital Adrenal Hyperplasia | ACTH causes adrenal hyperplasia and overproduction og 17OHP and hormones
🗑
|
||||
| Familial Hyperinsulinism | Hypoglycemia (ranges from severe neonatal to mild childhood onset)
🗑
|
||||
| Familial Hyperinsulinism | ~45% ABCC8 and 5% KCNJ11 (AR), ~5% GLUD1 and 5% HNF4A (AD w anticipation)
🗑
|
||||
| Familial Hyperinsulinism | rx: IV glucose, diazoxide, etc, diet, pancreatic resection, avoid fasting
🗑
|
||||
| Isolated Gonadotropin Releasing Hormone (GnRH) Def | low LH and FSH w hypogonadism, +/- micropenis/cryptochidism, small testes, absent puberty, 60% anosmia (aka Kallmann), bimanual synkinesis
🗑
|
||||
| Isolated Gonadtropin Releasing Hormone (GnRH) def | FGFR1, PROKR2, PROK2, CHD7, FGF8 muts ~25% (AD), KAL1 ~10% (XL) muts/del
🗑
|
||||
| Isolated Gonadtropin Releasing Hormone (GnRH) deff | Testosterone, hCG in males and estrogen, progestins in females
🗑
|
||||
| PROP1 related combined pituitary hormone def | combined pituatary hormone def (CPHD) w GH, TSH, LH, FSH, and PrL +/- ACTH deficiencies, short stature, FTT in childhood
🗑
|
||||
| PROP1 related combined pituatary hormone def | PROP1 muts >98% (AR)
🗑
|
||||
| PROP1 related combined pituatary hormone def | rx: GH, L thyroxine, +/- testosterone or estrogens, +/- hyrocortisone
🗑
|
||||
| Achondoplasia and Hypochondroplasia | Rhizomelic short stature, macrocephaly/inc ICP; kyphosis, lordosis, narrowing interpedicular distance, trident hand, genu varum, cranio-cervial compression and spinal stenosis
🗑
|
||||
| Achondroplasia and Hypochondroplasia | dx: signs and x-rays;
FGFR3: Achondroplasia 98% G>A transition due to CpG results in Gly380Arg; Hypochondroplasia Asn650Lys C>A and 21% C>G
🗑
|
||||
| Achondroplasia and Hypochondroplasia | rx: cns shunt for ICP, sleep and cc apnea; otitis; orthopedics for gibbus, genu varum and spinal stenosis
🗑
|
||||
| Osteogenesis Imperfecta | Fx fater min trauma, +/- dentinogenesis imperfect (gray/brown) and HL (adults
🗑
|
||||
| OI type 1 | non-deforming with blue sclerae
🗑
|
||||
| OI type 2 | perinatal lethal
🗑
|
||||
| OI type 3 | progressively deforming
🗑
|
||||
| OI type 4 | variable OI with nl sclerae
🗑
|
||||
| Osteogenesis imperfecta | dx: FHx (fx/signs), X rays (fx, wormian, codfish vertebrae and oseopenia);
COL1A1/2 molecular test and/or biochemical analysis of type 1 collagen
🗑
|
||||
| COL1A1/2 ratio | 2:1
🗑
|
||||
| Osteogenesis Imperfecta | Molecular testing COL1A/2 detects 90% of OI types 1-4 (AD, >95% seq changes and 2% del/dup); biochemical detects 90,98,84,84% of OI types 1-4
🗑
|
||||
| Ostoeogenesis imperfecta | rx: orthopedic and otolaryngology management, periodic dental and hearing eval; bisphosphonates, oral alendronate or risedronate and GH may reduce fx, increase bone density and improve growth
🗑
|
||||
| OI V-VII | Fx, no dentinogenesis (D) or hearing loss; abnl vertebrae and hyperplastic callous
🗑
|
||||
| OI V | IFITM5 (AD)
🗑
|
||||
| OI VI | SERPINF1 (AR)
🗑
|
||||
| OI VII | CRTAP (AR)
🗑
|
||||
| OI VIII | Fx, no dentinogenesis or HL; short limb dwarfism, gracile long bones
🗑
|
||||
| OI VIII | LEPRE1 (AR)
🗑
|
||||
| OI IX | Fx, white to gray sclerae, short limb dwarfism, bowed limbs
🗑
|
||||
| OI IX | PPIB (AR)
🗑
|
||||
| Type II Collagenopathies | Achondrogenesis 2;
Kniest,
SED,
Stickler
🗑
|
||||
| Achondrogenesis Type 2 (Langer Saldino) | micromelic dwarfism, CP, short ribs and abnl vert; stillborn/neonatal death;
COL2A1 (AD)
🗑
|
||||
| Kniest | short stature and trunk (platysopondyly); hearing loss; myopia and retinal detach (MRD and cataract;
COL2A1 (AD)
🗑
|
||||
| Spondyloepiphyseal Dysplasia (SEDC) | flat face/CP, MRD, abnl vert, cervical myelopathy;
COL2A1 (AD)
🗑
|
||||
| Stickler | flat face, MRD and cataract, HL, CP +/- Robin;
COL2A1 (85%) and COL11A1 (10-15%)
🗑
|
||||
| Diastrophic dysplasia | short limbs, nl skull, hitchhikers thumbs, spine (scoliosis, lordosis, kyphosis), joint contractures and osteoarthritis, CP 1/3, cystic ears 2/3, club feet
🗑
|
||||
| Diastrophic dysplasia | clinical and radiologic confirmed by SLC26A2 >90% have seq variants
🗑
|
||||
| Diastrophic dysplasia | rx: PT, casting, ortho surgery with caution as deformities tend to recur, watch C spine for cord compression
🗑
|
||||
| Ehlers Danlos | 5 types:
1.classic (i and ii) 2. hypermobility (III) 3.kyphoscoliotic (vi) 4. vascular(iv)
🗑
|
||||
| Classic EDS (i and ii) | skin hyperextensible, abnl wound healing and joint hypermobility
🗑
|
||||
| Hypermobility EDS (iii) | soft skin, dislocation, pain +/- aortic dilation
🗑
|
||||
| Kyphoscoliotic EDS (vi) | friable, hyperextensible skin; scars, bruising, hypotonia, progressive scoliosis and fragile sclerea
🗑
|
||||
| Vascular EDS (iv) | thin, translucent skin; bruising, vascular rupture (12% death secondary to arterial or uterine rupture in pregnancy); GI perforation
🗑
|
||||
| Classic EDS (i and ii) | ~50% have COL5A1/2 seq, del/dup (AD)
🗑
|
||||
| Hypermobility EDS (iii) | TNXB haploinsufficiency; very rare (AD)
🗑
|
||||
| Kyphoscoliotic EDS (vi) | increase deoxypyrimidine/pyrimidine ration in urine (HPLC) due to def lysyl hydroxylase (PLOD1) activity (fibroblast); PLOD1 seq?; del/dups ~18% (AR)
🗑
|
||||
| Vascular EDS (iv) | COL3A1 seq >95%, del/dup 2% (AD)
🗑
|
||||
| Classic EDS (i and ii) | rx: care with sutures, ascorbic acid? avoid ASA and contact sports
🗑
|
||||
| Hypermobility EDS (iii) | rx: watch aorta and avoid cs/joint hyperextension
🗑
|
||||
| Kyphoscoliotic EDS (vi) | rx: ortho, opthal, pregnancy risk and avoid cs
🗑
|
||||
| Vascular EDS (iv) | avoid contact sports and arteriography
🗑
|
||||
| Marfan syndrome | ocular (myopia, ectopia lentis); skeletal (dolichosternomelia, pectus, scoliosis); aoritc dilation/tear/rupture/MV prolapse
🗑
|
||||
| Marfan syndrome | dx: FHx, exam (esp ectopia lentis and aneurysm); FBN1 seq 70-93%, dels/dups? (AD), 25% de novo
🗑
|
||||
| Marfan syndrome | rx: lens surgery, beta blockers/losartan for aortic dilation, surgery 5 cm or if 1 cm/yr; yearly opthal & ECHO; avoid contact sports, isometric; CV stimulants and LASIK; inc CV risk with pregnancy
🗑
|
||||
| Loeys Dietz syndrome | vascular (CNS, thoracic and abdominal arterial aneurysms/dissections) and skeletal (pectus excav/carin, scoliosis, lax joints, arachnodactyly and clubfeet).
🗑
|
||||
| LDS type I | 75%
hypertelorism, bifid uvula/CP and craniosynostosis
🗑
|
||||
| LDS type II | 25%
velvety/translucent skin; atrophic scars
🗑
|
||||
| Loeys Dietz | TGFBR1/2 in 95% (AD), 3/4 de novo
🗑
|
||||
| Leoys Dietz | rx: aortic dissection at smaller diameters than MFS, beta blockers, C spine instability, avoid contact sports and CV stimulants
🗑
|
||||
| Multiple Epiphyseal Dysplasia | joint pain (hips and knees), malformations (hands, feet and knees) and scoliosis;
50% had clubfoot, clinodactyly or CP at birth; adult Ht 150-180 cm
🗑
|
||||
| Multiple Epiphyseal Dysplasia | dx: clin and x-ray; SLC26A2 seq variants in ~100% (AR)
🗑
|
||||
| Multiple Epiphyseal Dysplasia | rx: orthopedic, avoid sports involving joint overload and caution with NSAIDs
🗑
|
||||
| Pseudoxanthoma Elasticum | affects elastic tissue skin, eye, CV and GI systems; skin (papules); retina (streaks and hemorrhage); GI bleeds, angina/claudication
🗑
|
||||
| Pseudoxanthoma Elasticum | dx: skin and eye findings and skin biopsy; ABCC6 seq ~90% both alleles w dels in 5-30% (AR)
🗑
|
||||
| Pseudoxanthoma Elasticum | rx: intraocular injections for macular degeneration; avoid contact sports, ASA, NSAIDs, retinal exams in pregnancy
🗑
|
||||
| Branchiootorenal Spectrum Disorders | ear pits, tags, anomalies causing deafness >90%; branchial fistulae/cysts and renal hypoplasia, dysplasia or agenesis
🗑
|
||||
| Branchiootic Syn (BOS) | BOR w/out renal anomalies
🗑
|
||||
| Branchiootorenal disorders | EYA1, SIX5, SIX1 seq, dups/dels in 40% (AD) with 10% de novo
🗑
|
||||
| Branchiootorenal disorders | rx: excision fistulae/cysts, ear surgery, aids, cochlear implants
🗑
|
||||
| Lowe syndrome | eyes: cataracts, glaucoma and poor vision; CNS: hypotonia, absent DTRs and 75-90% mild to severe delay; Renal: Fanconi, RTA, renal
🗑
|
||||
| Lowe syndrome | OCRL seq variant in 95% affected males and carriers (XL); enzyme in fibroblasts
🗑
|
||||
| Lowe syndrome | rx: remove cataracts, GERD; oral Na/KHCO3, PO4 and calcitriol; avoid contact lens
🗑
|
||||
| Polycystic kidney disease (AD) | late onset, bilateral renal cysts; liver and pancreatic cysts; CNS/aortic aneurysms and MVP; renal pain, hypertension, renal failure by 60 yrs
🗑
|
||||
| Polycystic kidney disease (AD) | dx: renal imaging; 85% PKD1 and 15% PKD2 most seq but few del/dups (AD); contiguous PKD1 and TSC2 del > PKD in utero and Tuberous Sclerosis; rare early onset PKD with neg FHx due to hypo morph PKD1 in trans
🗑
|
||||
| Polycystic kidney disease (AD) | rx: hypertension, pain, cyst decompression, nephrolithiasis, clip small and aortic replacement for large aneurysms; avoid nephrotoxic, caffeine and smoking
🗑
|
||||
| Polycystic kidney disease (AR) | neonates with enlarged echogenic kidneys: ~45% hepatomegaly, dilated bile ducts and echogenicity; pulmonary hypoplasia w 30% dying by 1 yr of resp insuff and >50% have renal failure in first decade
🗑
|
||||
| Polycystic kidney disease (AR) | dx: clin findings in absence of renal cysts in parents; ~80% PKHD1 seq variants, dups/dels seen
🗑
|
||||
| Polycystic kidney disease (AR) | rx: resp failure, hypertension, avoid NSAIDS, aminoglycosides and caffeine
🗑
|
||||
| UMOD associated kidney disease | hyperuricemia and goat from dec renal excretion uric acid; increase creatinine 5-40 yrs and renal failure >40 yrs; isosthenuria may exacerbate bouts of dehydration
🗑
|
||||
| UMOD associated kidney disease | UMOD (aka uromodulin/Tamm Horsfall protein) seq variants in >95% (AD)
🗑
|
||||
| UMOD associated kidney disease | rx: allopurinol/probenecid for gout; nepherology management, peritoneal dialysis, renal transplant; avoid nephrotoxic meds, dehydration and meats
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
amrs
Popular Genetics sets