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N130 OLOL Diabetes Mellitus Terminology

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Answer
ADA diet   (blank)  
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Alpha Glucosidase inhibitors   A new class of drugs used in the treatment of non insulin dependant diabetes  
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Bigunides   a memeber of the class of oral antihyperglyceric agents that works by limiting glucose production and glucose absorption and by increasing the body's sensitivity to insulin.  
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Continous subcutaneous insulin infusion   (blank)  
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dawn phenomenon   a marked increase in insulin requirements between 6am and 9am as compared with the midnight to six am period.  
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Diabetic Ketoacidosis   acidosis caused by an accumulation of ketone bodies in advanced stages of uncontrolled diabetes mellitus.  
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Diabetes Mellitus   A chronic metabolic disorder marked by hyperglycemia.  
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Exchange lists   A grouping of foods to assist people on special diets  
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Fasting blood glucose (FBG)   fasting levels of blood glucose normally between 80 and 120  
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Gastric stasis   (blank)  
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Glucagon   A polypedtide homone secreted by teh alpha cells of the pancreas that increases the blood glucose level by stimulating the liver to change stored glycogen to glucose.  
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Gluconeogenesis   The formation of glucose from excess amino acids, fats, or other noncarbohydrate sources.  
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Glucose tolerence test   testing the ability of the body to absorb and use glucose.  
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Glucosuria/Glycosuria   An abnormal amount of glucose in the urine.  
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Glycemic index   A ratio used to describe the ability of a food to increase blood sugar as compared with consumption of either glucose or white bread as the standard.  
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Glycosylated hemoglobin test ( hemoglobin A1C)   Hemoglobin A that contains a glucose group linked to the terminal amino acid of the beta chains of the molecule.  
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Hyperglycemia   Increased blood sugar, as occurs in diabetes  
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Hypoglycemia   An abnormally low level of glucose in the blood often associated with neurological side effects and arousal of the sympathetic nervous system  
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Hyperglycemic Hyperosmolar Non ketotic Syndrome (HHNS)   (blank)  
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Impaired fasting glucose (IFG)/impaired glucose tolerance (IGT)   (blank)  
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Insulin   A hormone secreted by the beta cells of the pancreas that controls the metabolism and cellular uptake of sugars, proteins, and fats.  
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Islet cell transplant   Guided by sophisticated imaging equipment in Interventional Radiology, doctors inject the cells into the patient’s liver through a catheter inserted into a major blood vessel, the portal vein.  
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Ketone   A substance containing the carvonyl group attached to two carbon atoms.  
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Ketonemia   The presence of acetone bodies in the blood which causes the characteristic fruity breath odor in ketoacidosis.  
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Ketonuria   Acetone bodies in the urine  
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Kussmaul respiration   Kussmaul's breathing- a very deep gasping type of respiration associated with severe diabetic ketonacidosis  
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Macroangiopathy   Disease of the blood vessels (arteries, veins, and capillaries) that occurs when someone has diabetes for a long time. In macroangiopathy, fat and blood clots build up in the large blood vessels, stick to the vessel walls, and block the flow of blood.  
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Microangiopathy   Pathology of small blood vessels.  
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Meglitinides   type 2 medications that increase first phase insulin release in the pancreas  
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Metabolic Acidosis   Any process that causes a decrease in ph of the body as a result of the retention of acids, or the loss of bicarbonate buffers.  
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Metformin Induced lactic acidosis   Metformin is a useful anti-hyperglycaemic agent but significant mortality is associated with drug-induced lactic acidosis. Significant renal and hepatic disease, alcoholism and conditions associated with hypoxia (eg. cardiac and pulmonary disease, surgery  
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Neurogenic bladder   Any dysfunction of the urinary bladder caused by lesions of the central nervous system or nerves supplying the bladder.  
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Nephropathy   Disease of the kidney  
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Osmotic diuresis   is urination caused by the presence of certain substances in the kidney tubules. Excessive amount of glucose (blood-sugar) can cause this.  
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Peripheral Vascular Disease   Any condition that causes partial or complete obstruction of the flow of blood to or from the arteries or veins outside the chest.  
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Polydipsia   excessive thirst  
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Polyphagia   eating abnormally large amounts of food, gluttony  
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Polyuria   Excessive secretion and discharge of urine  
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Proteinuria   Protein, usually albumin, in the urine  
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retinopathy   Any disorder of the retina  
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Renal Threshold   the concentration at which a substance in the blood normally not excreted by the kidney begins to appear in the urine.  
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Self monitoring of blood glucose (SMBG)   (blank)  
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somogyi effect   In diabetes mellitus rebound hyperglycemia following an episode of hypoglycemia caused by counterregulatory hormone release.  
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Sulfonylureas   One of a class of oral durgs used to control hyperglycemia in type two diabetes mellitus. Members of this group include tolazamide, glyburide, and glipizide  
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Thiazolidinedione   An oral drug that lowers blood sugars by decreasing hepatic glucose output and increasing glucose metabolism in skeletal muscles.  
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Type 1 DM   Diabetes mellitus that usually has its onset before the age of 25 years in which the essential abnormalties is related to absolute nsulin deficiency.  
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Type 2 DM   A group of forms of diabetes mellitus that occur predominantly in adults.  
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