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Micro Final
Viruses
| Question | Answer |
|---|---|
| Peter Meadewor | "Piece of Bad News Wrapped Up" |
| A piece of genetic marterial (RNA or DNA) wrapped up in a protein coat called a capsid. | Virus |
| Nucleocapsid | Virion |
| Virion | Virus particle |
| Virus | No metabolic activity; No organelles; No cystosol; No liquid |
| There may be some enyzmes within host. Enyzmes are not active in the virus. Just taken with them from the host | Virus |
| Basic structure | Nucleic acid, Capsid, Membrane envelop |
| Envelop | Bilipid layer around Nucleocaspid |
| Acquired when it exjt the host | envelop |
| Envelop | used for protection(hide form immune system of host). |
| Used for recognition for attachment | Envelop |
| Also fused with another cell of host | Envelop |
| Capsomere | Protein subunits of the capsid |
| Naked virus | Non-evelope virion |
| Spikes | carbohydrate-protein complexes that project fromthe surface of the envelopes; |
| Used by some viruses to attach to host. | Spikes |
| bacteriophages or phages | viruses that can infect bacteria |
| obligatory intracellular parasites | absolutely require living host cellss in order to multiply. |
| the spectrum of host cells the virus can infect. | host range |
| Nucleic acid structure | DNA or RNA |
| Single or double standed: RNA may pair up | Nucleic acid structure |
| Linear, circular, or segmented chromosomes | Nucleic acid structure |
| Nucleic acid structure | RNA genomes unique to viruses |
| Nucleic acid enclosed by a | capsid |
| Capsomere | Individual subunits that make up the capsid |
| Has 1 protein or more proteins | capsid |
| capsid | proteins useful in identification; highly specific |
| helical viruses | resemble long rods that may be rigid or flexible |
| Ex: Ebola hemorrhagic fever and rabies | helical viruses |
| Ex: Tobacco Mosiac Virus and SARS | helical capsid |
| polyhedral capsid | many sided |
| 2 types of capsid | helical & polyhedral |
| Icosahedron capsid | 20 sides |
| Ex: Poliovirus | icosahedral virus |
| Complex capsid | bacteriophages |
| Ex: rabies | complex virus |
| Ex:Poliomyelitis & herpes simplex & Rubella | polyhedral |
| Can live on surfaces | naked virion |
| naked virion | more resistant to harsh conditions. |
| A virus that is very fragile. | An envelope virus |
| Contracted by droplet nuleci or blood or sexual contact | An envelope virus |
| Poxvirus | small pox |
| Paramyxovirus | Influzena |
| Larger viruses about 200 to 300 nanometer | poxvirus & paramyxovirus |
| Old scheme (host) | Based what they could infect |
| Based on the DNA or RNA they have | New scheme |
| ICTV | International Committee of Taxnomy on Viruses |
| Virus classification | RNA, DNA, nucleic acid, shape, envelope, and size |
| Classification naming | ICTV |
| lytic cycle | ends with the lysis and death of the host cell |
| lysogenic cyle | host cell remains alive |
| Attachment, penetration, synthesis, assembley, and release | Lytic replication of bacteriophage |
| attachment | phage attaches to host cell |
| penetration | phage pentrates host cell and injects its DNA using an enzyme called lysozyme in its tail to break the host cell walls down to enter the cell |
| synthesis | phage DNA directs synthesis of viral components by the host cell |
| viral components are assembled into virions | maturation |
| release | host cell lyses and new virions are released |
| lysogeny | the phage reamins latent (inactive) |
| prophage | the circle can recombine with and become part of the circular bacterial DNA |
| RNA viruses (non-envelope) | Picornavirus |
| Reovirus | RNA viruses (non-envelope) |
| RNA viruses (envelope) | Toga virus; Rhabdovirus; Coronvirus; Orthomyxovirus; Paramyovirus; Bunyavirus; Arena virus; Retrovirus |
| Picornavirus | 24 hr bug/Cold/Hep A |
| Reovirus | Gasterointestinal/Respiratory Infections |
| German Measles/Rubella | Toga virus |
| Rabies | Rhabdovirus |
| Coronavirus | SARS |
| Influena | Orthomyxovirus |
| Measles | Paramyxovirus |
| Bunyavirus/Huntavirus | Hemoraic fever |
| Arenavirus | Alsa fever |
| Retrovirus | HIV/Human T-cell leukemia |
| DNA (non-envelope) viruses | Parvovirus; Papovirus; Adenovirus |
| Hepadnavirus; Poxvirus; Herpesvirus | DNA (envelope) Viruses |
| Erythemia (5th disease) | Parvovirus |
| Papovavirus | Papilloma causes warts on epitheial cells |
| Adenovirus | Cause respiratory infections |
| Hep B | Hepadnavirus |
| Poxvirus | Smallpox/Cowpox |
| Herpes virus | Chicken pox; Shingles; Oral & Vaginal Herpes |