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MICRO4
Viral and Prion Nervous System Diseases
| Question | Answer |
|---|---|
| What diseases are involved with RABIES? | Furious rabis and paralytic rabies |
| How do you acquire the disease? | Through an animal vector |
| What is the process of the disease? | 1. Bite 2. Replicate in muscle 3. Get to PNS via spinal cord 4. Encephalitis 5. SPREAD EVERYWHERE |
| Diagnosis of this disease is? | Fourescent antibody assay on brain tissue |
| Treatment? | Rabies Immune Globulin (RIG) |
| Prevention of disease? | Vaccination and CDC watches for it |
| What are ENCHEPHALITIS arboro viruses? | Mosquito borne viruses |
| What are the six types of encephalitis causing things? which is the worst? | East, west, st. louis, california, venezuelan, and West Nile Virus; ALL ARE EQUALLY BAD |
| What conditions are associated with encephalitis and who is likely to be affected? | symptoms include, chills, headache, fever, confusion, coma; elderly are most affected |
| How do we diagnose it? | Indirect ELISA that detect IgM |
| Treatments? | non, really...Antiinflammatory |
| How do we prevent infection? What is it specifically? | Insecticides and repellents (DEET) |
| FUNGAL DISEASES | FUNGAL DISEASES |
| How is CRYPTOCOCCUS NEOFORMANS acquired? and from what location? | Inhaled via pigeon droppings and is in urban areas |
| Where does it spread? | CNS and meninges |
| What kind of virulence factor does it have? | THICK capsule |
| What is a treatment for this FUNGAL disease? | Amphotericin B and Flucytosine |
| How is it diagnosed? What are you testing for? | Latex agglutination for crytopoccal antigens |
| What are some other CNS diseases that involve prions in animals? | Sheep scarpie, bovine spongiform encephalopathy (mad cow) |
| What is the infectious agent made of in BSE? | Protein (not nucleic acid), |
| What is Kuru disease due to? | Cannibalism in New Guinea |
| Creutzfeldt jakob disease causes what: How many cases p/y? What kind of symptoms associated with it? | Holes in brain, 200 cases, and has alzheimer like sympotms |