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MICRO4
Nervous System Diseases
| Question | Answer |
|---|---|
| NEISSERIA MENINGITIDES | NEISSERIA MENINGITIDES |
| ID it: | Gram negative diplococci |
| What virulence factor does it have and of what serological groups? | Capsule of group A, B, C |
| What disease does it cause? and at what age? | Meningitis; for those <2 yr |
| What conditions are associated with Nisearia meningitides? | Meningococcemia |
| What is meningococcemia? | septecemia that is rapidly fatal |
| EPIDEMIOLOGY | EPIDEMIOLOGY |
| Where would you find it? | Throat and nasopharynx |
| Is it spreadable? | Yes, quickly contain it |
| How would you diagnose and treat it (at what speed, too)? | Gram stain of CSF, culture and sero type it; TREAT QUICKLY with abs |
| How do we prevent it? What have we been able to prevent? Have we prevented all? | Use a vaccine to prevent it. We have vaccines for A, C, but not B |
| What is the ID of STREPTOCOCCUS PNEUMONIAE? | Gram positive Cocci in pairs |
| What is the ID of LISTERIA MONOCYTOGENES? | Gram positive ROD |
| BACTERIAL INFECTIONS WITH TOXEMIA | TOXEMIA |
| What are the characteristics (Gram, type of growth, virulence) of CLOSTRIDIUM TETANI? | Gram Positive obligate anaerobe, and is a spore former (tetanus toxin) |
| What DISEASES are associated with it: | Nenatal and adult tetanus |
| What does nenonatal tetanus involv? and how is it caused? | Umbilical stump infection b/c of contaminated equipment |
| What is ADULT tetanus AKA? | lock-jaw |
| What is the process of infectino and type of infection invovled in this cause (reverse orderwhen answering and end with what specifically causes you to die?) | Rusty nail infection formed. Steps are: 1. Release toxin 2. PNS cells 3. CNS 4. Spastic muscles-->respiratory failure |
| EPIDEMIOLOGY | EPIDEMIOLOGY |
| What condition is most common in poor countries? | Nenonatal |
| What is a toxoid? | Similar to toxin, but no sporagenic effects |
| How would you treat it? Which is most important? | Debridement (remove dead tissue), TIG (passive vaccine that only works a few times), and VACCINE |
| What sort of vaccinations are out there for it? | Tetanus toxoid and DTP vaccine |
| BACTERIAL INFECTIONS OF THE PNS | PNS INFECTIONS |
| What is toxemia due to? | Exotoxin |
| Why are conjugate vaccines good? | Stuck to small protein (exotoxin) and good AB response |