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Physiology-Lecture 5
METABOLISM AND CELL SIGNALING
| Question | Answer |
|---|---|
| How is excess glucose stored? | Glycogen |
| Where is the glucose stored? | In liver and skeletal muscles |
| When is the glycogen formed? | 1st glycolysis step |
| Where is glycogen broken down? | Liver |
| Why is glucose important in our body? | Needed for nervous system functioning |
| Can a fat molecule become glucose? | NOOOOOO |
| What are adipocytes? | Fat cells, where the majority of energy is stored as triglycerides during food uptake |
| At rest, where does half of our energy come from? | from fat breakdown |
| How much ATP can we get when we break down one fatty acid? | 146 ATP molecule |
| Can glucose become fat? How so? | Yes!! Too much sugar makes me fat. You'd need intermediates like pyruvate or acetyul coA |
| What does the process of fat breakdown begin with? | Beta oxydation |
| What is this process? | Split off a Acetyl co-A from fatty acid to transfer 2 hydrogen atoms |
| Where do the by-products of the beta oxydation feed into? | Krebs cycle-->ETC |
| PROTEIN BREAKDOWN | PROTEIN BREAKDOWN |
| What breaks the peptide bonds in the proteins? | Enzyme protease |
| How is the amino group in the amino acid removed? | Deamination and transamination |
| What is the process of deamination? | Amino group gives rise to a molecule of ammonia and is replaced by an oxygen atom derived from water (KETO) |
| What is transamination? | Transfer of the amino group of an amino acid to a KETO |
| What does transamination result in? | An amino acid |
| What happens to the rest of the amino acid once the amino group is removed? | It can enter the krebs cycle |
| What is a major waste product of protein catabolism? | Urea |
| Do we get a lot of ATP from protein catabolism? | NOpe |
| Our bodies can make how many amino acids? | 11 |
| Where can we get the rest? | From food we need (need variety of food) |
| Can we do this reaction: Acetyl-Co A-->pyruvate? | No, the reaction of pyruvate to acetyl coa is irreversible |
| What are the categories of the essential nutrients? | 20 mineral elements, 2 fatty acids, 14 vatamins, and 9 amino acids |
| Can a fatty acid be converted to glucose? | NO!!! B/c you can't reverse going from pyruvate to acetyl co-A |