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Anatomy 5--Cytology

Various structures and functions within the cell

QuestionAnswer
What are some examples of cell types? Neurons, cells that conduct electricity; hormones...etc.
Why are cells diverse? The way there are many unique proteins in the cell
What is the nucleus? Contains the instruction manual of the cell, which are genes within DNA chrmosomes.
How many genes do we have? 3 billion
DNA: Double helix ladder structure of base pairs
What's another word for base pairs? Nucleotides
What is transcription? Occurs in nucleus, where DNA splits apart to find nucleotide that assembre to compliment the single chain
What is this compliment called? mRNA
What is important to note about the new compliment? T is replaced with Uracil
What happens after the mRNA is created? It leaves through the pores of the nucleous to go to the cytoplasm, where it is translated into a protein
What is an example of Transcription? Making a muscle cell
Orgennelles: and what are they also known as? Located in the cytoplasm (baby cells, not yet formed) Stem cells
What does the mRNA do once it arrives at the cytoplasm? It finds the ribosomes so they can make proteins
What is the overall function of mRNA? Provides insturction for the ribosomes to make a protein
How do the ribosomes start the protein making process? They assign each codon an amino acid
Codon: Series of 3 nucleotides in a row
What is translation: Occurs in ribosomes, makeing protein by attaching amino acids to it.
What makes up a cell? Proteins
What can have the potential to kill a cell, and how? Ricin or anthrax because it shuts down ribosomes, so they can't make proteins
What is the function of the smooth ER? Lipid production and detoxification
Rough ER function: Where proteins are made
After the rough ER makes proteins, where do they go? To the Golgi app
What's another word for the Golgi app? Golgi complex
What does the Golgi do to the protein? It modifies it
What's the number one way the Golgi modifies a protein? Adds sugar to it
What is the overall function of the protein, in formal words? Post translational changes to protein to let it know where to go
How many main fates does a protein have, and what are they? Three fates: secretion, storage, and become a membrane vesicle
What is an example of a protein secreted by the cell? Can be secreted out of the cell in the form of a hormone
Example of a storage protein in a cell? Enzymes
What are digestive enzymes? Lysosomes
Autoimunal disease: When lysosomes break down a healthy cell
Lysosomes in cytoplasm, contain digestive enzymes that rid the cell of waste
What's the slang word for lysosomes: Suicide bags
How is hydrogen peroxide formed in the body? by product of metabolism
Peroxisome Digestive enzyme that catalyzes the production and breakdown of hydrogen peroxide
What does a membrane vesicle do? becomes part of the plasma membrane
Intracellular: Everything in the cell
Extracellular: everything OUTside of the cell
What are some characteristics of the plasma membrane: A phospholipid bilayer that is selectively permeable to protect the cell
Where do the phospholipid heads face? Intra or extra? Hydrophilic
Where do the tails face? Hydrophobic
What is the function of cholestrol in the cell? Makes plasma membrane fluid
Transmembrane protein: Spans lipid bilayer, from hydrophobic to hydrophillic
Peripheral protein: On one side, either extra cell surface or intracell surface
What is an example of a peripheral protein? Receptor
glycolipid: Sugar on a lipid
Glycoprotein: Sugar on protein: added by Golgi
What is sugar coating Glyco Calyx
Where does transcription take place? Nucleous
Where does translation take place? In ribosomes
Where are phospholipids made? Smooth ER
What is the function of the glyco calyx? Cell ID as self vs. foreign ID
What is an example of cell ID methods? The ABO blood typing
What is hemolytic referring to? When one breaks blood cells, which leads to clots
How can hemolytics occur? When you add the wrong blood type to someone
What is the "thing" around the red blood cell, that really makes up the red blood cell? What is its formal word? Protein called antogen
Antogen: Initiates a new reaction
What is another word for antogen? Agglutinogen
How does the body reacts when a type A bloodtype receives a type B blood transfusion? Type A blood has type B antibodies which would cause hemolytic reactions
What is another word for those antibodies? Agglutinim
What antibodies does type B have? Type A
What antibodies does type AB have? No antibodies
What blood type does type O have? A and B
What is referred to as the universal donor? O
What is the universal receiver? AB
What are the type O proteins? No proteins
Where are the plasma memrane proteins produced? In the liver
Where is an unlikely location to find blood cell receptors? Plasma membrane
What are two ways to transport stuff accross plasma membrane? Active and passive transport
How is active transport possible? Through ATP
Where is ATP produced? Mitochondria
What is myopathy? A muscle problem caused by mitochondria not producing proteins
What area of the body isi most affected by a problem in the mitochondria? The muscles, because they need a lot of ATP to move
What is the life cycle of the cell in which the cell performs normal metabolism and spends most of its time here? Interphase
Why do cells divide? To repair themselves
What is DNA called in its uncodensed format? Chromatin
What is DNA in its condensed format? Chromosomes
Where does the cell spend its shortest amount of time? Dividing, it is mostly in metabolism
What are the five stages of mitosis? Interphase, prophase, metaphase, anaphase, telophase
What happens in prophse? dna condenses
what happens in metaphse? chromosomes line up
what happens in anaphase? mitotic spindles form
What happens in telophase? the cleavage furrow forms
What is cytokinesis? At the tail end of telophse, it is where the cytoplasm is divided
What signals the start and stop of mitosis? Proto-onco genes
what specific gene tells the cell to stop dividing? TSP
What is it called when cells die? Necrosiss
What is programmed cell death called? Apoctosis
What is an example of apoctosis: The webbing on the hands and feet in fetusses
What is the result of the surface of the skin of necrosis? Inflimation
What is a tumor? Uncontrolled cellular division
What is a primary example of a cell that does not have a nucleous? Red blood cells
What is oncology? Cancer research; how to start and stop cell cycle
What is the life cycle of a cancer cell? it spends little time in interphse, most of the time in division
What is an example of cells that do not divide? Muscle or nerve cells, we are born with all these cells
What is a stratified squamus: Skin cells, or cells that come in contact with stuff
Carcinogenes? Cancer causing genes
What is the cytoskeleton? Shape, organization, growth and development of cell is taken care of by the cytoskeleton
What is responsible for the movement of the chromosomes during cell division? Microtubules
What happens in G1: duplicates organelles, replicates centrosomes
What happens in G2: Cell grows, enzymes and proteins synthesized
Mitosis: When cell division occurs
What are the functions of membrane proteins? ion channels, transporters, receptors, and linkers
Ex of membrane proteins acting as ion channels? sodium pump
receptors: cell cell recognition
Linkers: anchor proteins of neighboring cell's PM
What is cytosol? Intercellular fluid
What is plasm? Extracell fluid in plasma
intestinal fluid? microscopic fluid between tissues
Example of simple diffusion: oxgen going to cells
fascillitated diffusion: integral proteins help out by providing thing some way to get to PM
Filtration: water or dissolved substance moves via blood pressure
What is endocytosis: receptor mediated; receptor binds to particle to make a vesicle
example of endocytossi: getting choloestrol into cell
What is the process of endocytosis: binding, vesicle formation, uncoating, fusiion with endosome, recyling to PM, and lysosome eats it.
AIDS, how does it work? attaches to cd4 receptor, present in PM of t-cells
phagocytosis: cell eating
when is phagocytosis used? When there's a pathogen present, it becomes engulfed, fuses with lysosome and bye bye baby
what is the process of exocytosis: getting stuff out of cell in which ship fuses with PM and releases waste
What does cytosol do?? catalyzes chemical reactions
What is the function of microfils? increase surface area, great for absorption
interfils: help ancho organnelles together
centrosomes: Where the mitotic spindle grown
What are the functions of smooth ER? Make steroids, fats, and helps build up some resistance to drugs
In which surface of golgi does stuff enter? what does this face? CIS, faces RER
Which surface does it exit from? Trans: faces PM
What is tay sachs disease? absence of hex A, which breaks down stuff in nerve-->blind
What is proteasosome? What is it supposed to do and what is the pathophysiology associated with it? It is supposed to degrade misfolded proteins in brain-->cystic fibrosis
What is the function of nucleolous? Makes mRNA
what the heck are telomers and how are they related to aging? DNA at the tip of chromosomes, they lose function after a lot of growth, so cells don't divide...
What is the function of glucose in proteins and the cell in general? creates more crosslinks, stiffness
What is progeria? When you die at 13 because telomeres are shorter than usual
Werner syndrome? rapid aging
What is the role of adenomas in cnacer? it is the division of cell that leads to p 53 mutation
Created by: talkglitter2486
 

 



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