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Spirochetes
MedMicro 2006 UTHSCmed
| Question | Answer |
|---|---|
| Treponema pallidum Shape | helical bacillus (long and thin) |
| Treponema pallidum aerobicity | microaerophilic |
| Treponema pallidum motility | peroplasmic flagella, cork-screw |
| Treponema pallidum Reservoir | Humans |
| Treponema pallidum diseases | Syphilis |
| Treponema pallidum specimen | exudate from skin |
| Treponema pallidum lab diagnosis | Darkfield microscopy, non- & triponemal tests, characteristic lesions |
| Treponema pallidum treatment | penicillin (in secondary, can cause Jarisch Herxheimer reaction:fever, chills) |
| Treponema pallidum prevention/control | safe sex!, screening of pregnant women |
| Treponema pallidum NOTES: | obligate parasite of humans |
| Treponema pallidum Neurosyphilis | mental illness, shuffling gate |
| Treponema pallidum LATE congenital syphilis | Hutchinson's teeth (notched incisors) and interstitial keratitis (cloudy eye) |
| T. pallidum pertenue = | Yaws |
| T. carateum = | Pinta |
| T. vincenti & denticola = | Dental Caries |
| T. pallidum endemicum = | endemic syphilis |
| Brachuspira pilosicoli = | gut flora? |
| B. hyodysenteriae = | dysentery in pigs |
| Borrelia recurrentis & hermsiiShape | Helical bacillus |
| Borrelia recurrentis & hermsii Aerobicity | microaerophilic |
| Borrelia recurrentis & hermsii Motility | flagella |
| Borrelia recurrentis & hermsii virulence factors | Variable Major Protein: antigenic variants cause cycles/relapses |
| Borrelia recurrentis & hermsii reservoir | rodents + ticks, humans + lice |
| Borrelia recurrentis & hermsii specimen | Blood |
| Borrelia recurrentis & hermsii NOTES: | mimics: leptospirosis, typhus, typhoid fever, and malaria |
| B. burgdoferi shape | Helical bacillus |
| B. burgdoferi aerobicity | microaerophilic |
| B. burgdoferi motility | highly motile |
| B. burgdoferi reservoir | Mouse, deer + tick |
| B. burgdoferi specimen | serum, skin biopsy |
| B. burgdoferi lab diagnosis | serology (most), culture (rare), PCR (rare) |
| B. burgdoferi treatment | Ter/doxycycline (early); ceftriaxone, penicillin (late), amoxicillin (both) |
| B. burgdoferi prevention/control | DEET, white socks over pants, avoidance |
| B. burgdoferi NOTES: | promary erythemia migrans from wound site, secondary cardio/neuro/opthalmo, terthiary chronic (arthritis, dermititis) |
| Leptospira interrogans shape | Helical bacillus |
| Leptospira interrogans aerobicity | Aerobe |
| Leptospira interrogans Temperature | 30 C |
| Leptospira interrogans reservoir | mammals: urine |
| Leptospira interrogans diseases | leptospirosis: rash, fever, shiclls, in stages; rare Weil's syndrome |
| Leptospira interrogans specimen | blood, CSF, urine |
| Leptospira interrogans treatment | no standard: doxycycline, Beta-lactams, streptomycin |
| Leptospira interrogans prevention/control | Avoid urine or contaminated water |
| Primary syphilis | Chanchre |
| Secondary syphilis | Rash |
| Terthiary syphilis | latent, neuro, gummatour, or cardio; congenital (severe) |
Created by:
Garzilla