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Campy/Helicobacter

MedMicro 2006 UTHSCmed

QuestionAnswer
Camp and Helico all bacillus(curved, Microaerophilic, Oxidase +, Catalase +, NON-fermenting
Campylobacter jejuni shape Bacillus (curved)
Campylobacter jejuni aerobicity Microaerophilic
Campylobacter jejuni Oxidase +/- ? Oxidase +
Campylobacter jejuni Catatlase +/- ? Catalase +
Campylobacter jejuni fermeter? Non-fermenting
Campylobacter jejuni motility single flagellum
Campylobacter jejuni Temperature 32-42 C
Campylobacter jejuni virulence factors adhesion, enterotoxin
Campylobacter jejuni pathophysiology consumption of bad water or food; usually self-limiting
Campylobacter jejuni reservoir birds and mammals
Campylobacter jejuni diseases acute gastroenteritis/dysentery; guillan-barre syndrome (rare autoimmune peripheral demyeleniaton
Campylobacter jejuni Specimen stool
Campylobacter jejuni lab diagnosis Campy selective blood agar, 5% O2, thermophile, fastidious, slow
Campylobacter jejuni treatment Ciprofloxacin (adults) and erythromycin (kids)--only in severe disease or to eliminate carrier state
Campylobacter jejuni prevention/control Properly prepared food, pasteurization, sanitary water
Campylobacter jejuni NOTES: Resistant to many antibiotics, similiar to Vibrios except non-halophilic
Campylobacter jejuni NOTES: Peaks in Warm months, low stomack acid is risk
C. fetus Shape Bacillus (curved)
C. fetus Aerobicity Micoraerophilic
C. fetus Oxidase +/- ? Oxidase +
C. fetus Catalase +/- ? Catalase +
C. fetus fermeter? NON-fermenting
C. fetus motility single flagellum
C. fetus temperature 25-37 C
C. fetus virulence factors capsule-like s protein
C. fetus pathophysiology from GI tract to bloodstream
C. fetus reservoir cattle and sheep
C. fetus Diseases Systemic bacteremia
C. fetus specimen blood
C. fetus NOTES: infections are rare but often fatal; found in immunocompromised
Helicobacter pylori Shape Bacillus (curved)
Helicobacter pylori Aerobicity Microaerophilic
Helicobacter pylori Oxidase +/- ? Oxidase +
Helicobacter pylori Catalase +/- ? Catalse +
Helicobacter pylori fermeter NON-fermenting
Helicobacter pylori motility 5-6 polar flagella
Helicobacter pylori temperature 35-42 C
Helicobacter pylori virulence factors Urease, adhesion, LPS, micinase, phospholipase, VacA, acid inhibitory protein
Helicobacter pylori pathophysiology Ingestion, invades mucus over gastric epithelium; Type I = vacuolating cytotoxin (VacA), duodenum
Helicobacter pylori Reservoir humans
Helicobacter pylori Diseases gastric and duodenal ulcers, gastritis; gstric adenocarcinoma and MALT B-cell lymphomas
Helicobacter pylori specimen gastric or duodenal biopsy, breath test for urea
Helicobacter pylori lab diagnosis blood antibodies, difficult to culture
Helicobacter pylori teatment Metronidazole + tetracycline or amoxicillin; Pepto Bismol + omeprazole (H+ pump inhibitor)
Helicobacter pylori prevention/control vaccine is being developed
Helicobacter pylori NOTES: Group 1 carcinogen(cigarettes), Infiltration of lamina propria w/ PMN's
Created by: Garzilla
 

 



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