| Question |
Answer |
| 1. What is mycosis |
a. An infection caused by pathologic fungus |
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2. Molds are |
a. Multicellular |
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3. Yeasts are |
a. Single celled organisms |
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4. Yeasts produce how |
a. By budding |
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5. Molds are characterized by what |
a. Long, branching filaments called hyphae |
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6. The most commonly used antifungal drug is by what method |
a. Topical |
|
7. Some examples of topical antifungal drugs are |
a. Clotrimazole (lotrimin), miconazole (monistat), nystatin |
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8. Fungi are difficult to treat because what reason |
a. Chemicals that kill fungi are not tolerate by humans |
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9. What is the oldest antifungal drug |
a. Amphotericin B |
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10. A major group of antifungal drug that includes: ketoconazole, miconazole, and clotrimazole |
a. Imidazoles |
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11. These require external carbon source |
a. Fungi |
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12. Another major group including: amphotericin b and nystatin is called what |
a. Polyenes |
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13. When giving an infusion of amp b, what s/e should you monitor for |
a. Chills, fever, and malaise |
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14. The drug of choice for systemic fungal infections is |
a. Amp b |
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15. 2 drugs that are used systemically are |
a. Amp b and fluconazole (diflucan) |
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16. s/e of amp b include |
a. Renal toxicity, neurotoxicity- seizures and praesthesias |
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17. What pretreatment may reduce the severity of infusion related reactions |
a. Antipyretic antihistamine and antiemetics |
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18. When using antifungals you should obtain what |
a. Baseline VS, CBC, liver function studies and ECG |
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19. If giving amp b IV, you should use what |
a. The most distal vein possible |
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20. Nystatin suspension, taken orally should be |
a. Swished in the mouth thoroughly as long as possible before swallowing |
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21. A problem of most concern in pts about to receive antifungal meds are |
a. Those with hepatic disease |
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22. A common underlying source of drug interactions with an antifungal are |
a. Cytochrome P-450 enzyme system |
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23. When taking griseofulvin, you should look for what potential s/e |
a. Blood dyscrasis |
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