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PATH 375 Ch15
| Word | Definition |
|---|---|
| vulva | (blank) |
| labia majora | (blank) |
| labia minora | (blank) |
| clitoris | (blank) |
| urethral orifice | (blank) |
| vagina | (blank) |
| cervix | (blank) |
| uterus | (blank) |
| fallopian tubules | (blank) |
| ovaries | (blank) |
| Discuss the histology of female reproductive system 3x | (blank) |
| stratified squamous mucosa | (blank) |
| glandular epithelium | (blank) |
| germ cells | (blank) |
| ectocervix | touchable part |
| endocervix | canal part |
| endometrium | glandular epithelium |
| Hermaphroditism (1) defn (2) types | (blank) |
| True hermaphroditism | (blank) |
| male pseudohermaphroditism | inside male, outside female |
| female pseudohermaphroditism | inside female, outside male |
| How many female developmental abnormalities did we studied? | 1x Hermaphroditism |
| STD: female & male [chart] | (blank) |
| Is STD common? | yes |
| What are the usual symptoms of STD? | 1. vaginal discharge 2. leision 3. pelvic pain 4. dyspareunia |
| dyspareunia | painful intercourse |
| Female viral STD | 2x HSV HPV |
| HSV Type 2 (1) symptoms (2) on-set (3) rate (4) dormancy? (5) notes | (1) vesicles fuse together (coalesce) & ulcerate (2) 3-7 days (3) 30% infected = leisons (4) yes. neural ganglion cells (5) don't give birth when active |
| HPV (1) symptoms (2) types (3) | (1) labial, vaginal, cervical warts (condyloma) (2) those that will become carcinoma AND those that won't (HPV 6, 11) (3) |
| warts | (blank) |
| condyloma | (blank) |
| carcinoma | (blank) |
| condyloma acuminatum | large wart (HPV 6, 11) |
| Female bacterial STD | 1 chlamydia 2 gonorrhea 3 syphilis |
| Chlamydia (1) agent (2) symptoms | (2) urethritis / cervicitis / discharge / PID |
| Gonorrhea (1) agent (2) symptoms | (2) urethritis / cervicitis / discharge / PID |
| Syphilis (1) agent (2) symptoms | (2) vulvar ulcers |
| coalesce | fusion, vesicles |
| Bacterial vaginoses (1) types | general bacterial infection of vagina 3x |
| Candida | (blank) |
| Trichomonas | (blank) |
| Gardnerella | (blank) |
| Pelvic inflammatory disease (PID) (1) defn (2) cause (3) symptoms (4) complications 4x | Neisseria, Chlamydia (4) salpingitis, tubo-ovarian abscess, peritonitis |
| salpingitis | fallopian tubule |
| tubo-ovarian abscess | (blank) |
| peritonitis | (blank) |
| Complications of PID | (1) chronic non-specific (2) infertility if scar (3) pelvic mass (4) pain (5) spread of infection |
| Endometrial hyperplasia (1) defn (2) cause 2kinds (3) types | (blank) |
| hypothalamic - pituitary - ovarian axis | (blank) |
| estrogen VS progesterone | (blank) |
| anovulatory cycle | (blank) |
| functional cause | (blank) |
| organic cause | (blank) |
| Complex endometrial hyperplasia | (blank) |
| simple endometrial hyperplasia | (blank) |
| atypical endometrial hyperplasia | (blank) |
| typical endometrial hyperplasia | (blank) |
| endometrial adenocarcinoma | (blank) |
| What is one common thing about cancer in vulva, vagina & cervix? | they're all squamous cell carcinoma |
| Carcinoma of vulva (1) types 1x (2) progression / appearance (3) diagnosis (4) treatment | (1) squamous cell carcinoma (2) at first pre-cancer white/red patch, then ulcer or lump (3) biopsy (4) 1surgery 2+/- adjuvant therapy |
| white or red patch | (blank) |
| adjuvant therapy | (blank) |
| Carcinoma of vagina (1) types 2x | 1squamous cell carcinoma 2 clear cell carcinoma |
| squamous cell carcinoma: female reprod cancer... | vulva, vagina, cervix |
| clear cell carcinoma | DES (40-70s pill to prevent spontaneous abortion) |
| DES | 40-70s pill to prevent spontaneous abortion - vaginal clear cell carcinoma |
| Carcinoma of cervix (1) types 1x (2) risk factors 5x (3) location (4) progression / appearance (5) grading (6) prevention (7) virus (8) notes | (4) progression: dysplasia -> carcinoma in situ -> invasive (6) pap smear (7) HPV 16, 18, 31, 33, 34, 35 (8) koilocytic changes |
| Pap smear | (blank) |
| venereal disease | sexual contact disease |
| cervical dysplasia | (blank) |
| cervical intra-epithlial neoplasia | CIN |
| CIN | (blank) |
| CIS | carcinoma in situ |
| transition zone | between squamous epithelium & columnar epithelium (endo/exo-cervix) |
| koilocytic change | HPV |
| HPV histology is.. | koilocytic change |
| Neoplasms of the uterus (1) types | (blank) |
| Leiomyoma (1)defn b/m (2) treatment (3) risk group (4) symtpoms | (1) b smooth muscle cell uterus (2) estrogen (3) reproductive age (4) usually asympt, mass, bleeding.. |
| fibroid | leiomyoma |
| most common uterine neoplasm is... | leiomyoma |
| Leiomyosarcoma (1) defn b/m (2) rate | (1) m smooth muscle uterus (2) rare |
| Endometrial adenocarcinoma (1) defn b/m (2) risk group (3) symptoms (4) risk factors 3x (5) stage/grade (6) diagnosis (7) treatment | (1)m epith cell endometrium (2) elderly f (3) vaginal bleed (4) 1tumor that secretes estrogen 2taking exogenous estrogen 3obesity 4nulliparous 5early menarche 6late menopause (5)I-IV/LMH (6)biopsy / dilation & curettage (7) hysterectomy +adjuvant treatmen |
| hyperestrinism | too much estrogen |
| what is the most common malignant tumor of female reproductive tract? | endometrium adenocarcinoma |
| estrogen secreting tumor | endometrium adenocarcinoma |
| take exogenous estrogen | endometrium adenocarcinoma |
| obestity is a risk factor for... | endometrium adenocarcinoma |
| nulliparous | (blank) |
| menarche | (blank) |
| menopause | (blank) |
| dilation and curettage | (blank) |
| hysterectomy | (blank) |
| adjuvant therapy | endometrium adenocarcinoma |
| ovarian cyst (1) defn (2) causes 3x (3) symptoms (4) big/small cyst? poly?single? | easily confused with cancer (1) follicules filled with fluid (2) 1follicles -> cyst 2cystic corpora lutea 3inclusion of surface cells (3) asymptomatic (4) small, single -- easily confused with cancer |
| unruptured follicles | ovarian cyst |
| follicular cysts | ovarian cyst |
| cystic corpora lutea | ovarian cyst |
| inclusion of ovary surface cells | ovarian cyst |
| Polycystic ovary syndrome (1) defn (2) symptoms (3) consequence | (1) hormone bad (2) no M (3) infertility |
| adrenal | kidney |
| Ovarian neoplasm (1) rate (2) types 3x (3) risk factors | (1) most death f ; 2nd common f reprof (2) surface, germ, stromal (3) ovarian dysgenesis, mutation BRCA1 BRCA2 |
| What cancer is the second most common group in female reprod tract? | ovarian |
| What cancer has highest mortality of female reproductive tract? | ovarian |
| Is ovarian cancer common in young female? | No |
| ovarian dysgenesis | (blank) |
| BRCA1 & BRCA2 | (blank) |
| Is oral contraceptives linked to ovarian cancers? | No |
| Surface epithelial tumors @ cervix (1) rate amg cervix cancer (2) types 5x | (1) highest 70% (2) serous, mucinous, endometrioid, clear cell, transitional cell |
| Which is the most common ovarian cancer? Surface?Germ?Stromal? | surface, 70% |
| serous epithelial tumor (1) secretion? (2) appearance (3) grading | (blank) |
| mucinous epithelial tumor (1) secretion? (2) appearance (3) grading | (blank) |
| endometriod epithelial tumor (1) secretion? (2) appearance (3) grading | (blank) |
| Germ cell tumor @ cervix (1) rate (2) risk group | (1) 20% (2) young f |
| what tumor will contain fat, hair and teeth/bone? | ovarian teratoma |
| Teratoma (female) | (blank) |
| Immature teratoma (female) | (blank) |
| sebaceous material | (blank) |
| dermoid cysts | (blank) |
| tumor of germ cells developed into neural tissues | (blank) |
| Fibroma | (blank) |
| fibroblast | (blank) |
| Thecoma | (blank) |
| Theca cells | spindle cells - produce estrogen |
| spindle cells | Theca cells - produce estrogen |
| Granulosa cell tumor | granulosa cell |
| Granulosa cell | produce estrogen |
| 4 Causes of infertility | (blank) |
| Asherman's syndrome | (blank) |
| ectopic pregnancy | rupture |
| trophoblast cells | epith lining of placental villi |
| placenta accreta | (blank) |
| placental villi | (blank) |
| placenta previa | (blank) |
| toxemia | (blank) |
| preeclampsia | (blank) |
| eclampsia | (blank) |
| Gestational trophoblastic disease (GTD) | (blank) |
| Hydatidiform mole (1) cause (2) consequence | chorionic villi - no fetal movement, high hCG |
| hydropic degeneration | (blank) |
| chorionic villi disease | (blank) |
| complete mole | no fetus / 46xx, all pateranl |
| incomplete mole | little fetus / 69 fmm |
| Choriocarcinoma | highly malignant, treat with methotrexate |
| methotrexate | Choriocarcinoma |
| What is abortion? | <500 g , 20wks |
| Rate of Spontaneous abortions | 1/3 of all preg |
| complete abortion | (blank) |
| incomplete abortion | (blank) |
| missed abortion | (blank) |
| threatened abortion | some live, some die |
| Endometriosis | (blank) |
| chocolate cyst | (blank) |