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PATH 375 Ch15

WordDefinition
vulva (blank)
labia majora (blank)
labia minora (blank)
clitoris (blank)
urethral orifice (blank)
vagina (blank)
cervix (blank)
uterus (blank)
fallopian tubules (blank)
ovaries (blank)
Discuss the histology of female reproductive system 3x (blank)
stratified squamous mucosa (blank)
glandular epithelium (blank)
germ cells (blank)
ectocervix touchable part
endocervix canal part
endometrium glandular epithelium
Hermaphroditism (1) defn (2) types (blank)
True hermaphroditism (blank)
male pseudohermaphroditism inside male, outside female
female pseudohermaphroditism inside female, outside male
How many female developmental abnormalities did we studied? 1x Hermaphroditism
STD: female & male [chart] (blank)
Is STD common? yes
What are the usual symptoms of STD? 1. vaginal discharge 2. leision 3. pelvic pain 4. dyspareunia
dyspareunia painful intercourse
Female viral STD 2x HSV HPV
HSV Type 2 (1) symptoms (2) on-set (3) rate (4) dormancy? (5) notes (1) vesicles fuse together (coalesce) & ulcerate (2) 3-7 days (3) 30% infected = leisons (4) yes. neural ganglion cells (5) don't give birth when active
HPV (1) symptoms (2) types (3) (1) labial, vaginal, cervical warts (condyloma) (2) those that will become carcinoma AND those that won't (HPV 6, 11) (3)
warts (blank)
condyloma (blank)
carcinoma (blank)
condyloma acuminatum large wart (HPV 6, 11)
Female bacterial STD 1 chlamydia 2 gonorrhea 3 syphilis
Chlamydia (1) agent (2) symptoms (2) urethritis / cervicitis / discharge / PID
Gonorrhea (1) agent (2) symptoms (2) urethritis / cervicitis / discharge / PID
Syphilis (1) agent (2) symptoms (2) vulvar ulcers
coalesce fusion, vesicles
Bacterial vaginoses (1) types general bacterial infection of vagina 3x
Candida (blank)
Trichomonas (blank)
Gardnerella (blank)
Pelvic inflammatory disease (PID) (1) defn (2) cause (3) symptoms (4) complications 4x Neisseria, Chlamydia (4) salpingitis, tubo-ovarian abscess, peritonitis
salpingitis fallopian tubule
tubo-ovarian abscess (blank)
peritonitis (blank)
Complications of PID (1) chronic non-specific (2) infertility if scar (3) pelvic mass (4) pain (5) spread of infection
Endometrial hyperplasia (1) defn (2) cause 2kinds (3) types (blank)
hypothalamic - pituitary - ovarian axis (blank)
estrogen VS progesterone (blank)
anovulatory cycle (blank)
functional cause (blank)
organic cause (blank)
Complex endometrial hyperplasia (blank)
simple endometrial hyperplasia (blank)
atypical endometrial hyperplasia (blank)
typical endometrial hyperplasia (blank)
endometrial adenocarcinoma (blank)
What is one common thing about cancer in vulva, vagina & cervix? they're all squamous cell carcinoma
Carcinoma of vulva (1) types 1x (2) progression / appearance (3) diagnosis (4) treatment (1) squamous cell carcinoma (2) at first pre-cancer white/red patch, then ulcer or lump (3) biopsy (4) 1surgery 2+/- adjuvant therapy
white or red patch (blank)
adjuvant therapy (blank)
Carcinoma of vagina (1) types 2x 1squamous cell carcinoma 2 clear cell carcinoma
squamous cell carcinoma: female reprod cancer... vulva, vagina, cervix
clear cell carcinoma DES (40-70s pill to prevent spontaneous abortion)
DES 40-70s pill to prevent spontaneous abortion - vaginal clear cell carcinoma
Carcinoma of cervix (1) types 1x (2) risk factors 5x (3) location (4) progression / appearance (5) grading (6) prevention (7) virus (8) notes (4) progression: dysplasia -> carcinoma in situ -> invasive (6) pap smear (7) HPV 16, 18, 31, 33, 34, 35 (8) koilocytic changes
Pap smear (blank)
venereal disease sexual contact disease
cervical dysplasia (blank)
cervical intra-epithlial neoplasia CIN
CIN (blank)
CIS carcinoma in situ
transition zone between squamous epithelium & columnar epithelium (endo/exo-cervix)
koilocytic change HPV
HPV histology is.. koilocytic change
Neoplasms of the uterus (1) types (blank)
Leiomyoma (1)defn b/m (2) treatment (3) risk group (4) symtpoms (1) b smooth muscle cell uterus (2) estrogen (3) reproductive age (4) usually asympt, mass, bleeding..
fibroid leiomyoma
most common uterine neoplasm is... leiomyoma
Leiomyosarcoma (1) defn b/m (2) rate (1) m smooth muscle uterus (2) rare
Endometrial adenocarcinoma (1) defn b/m (2) risk group (3) symptoms (4) risk factors 3x (5) stage/grade (6) diagnosis (7) treatment (1)m epith cell endometrium (2) elderly f (3) vaginal bleed (4) 1tumor that secretes estrogen 2taking exogenous estrogen 3obesity 4nulliparous 5early menarche 6late menopause (5)I-IV/LMH (6)biopsy / dilation & curettage (7) hysterectomy +adjuvant treatmen
hyperestrinism too much estrogen
what is the most common malignant tumor of female reproductive tract? endometrium adenocarcinoma
estrogen secreting tumor endometrium adenocarcinoma
take exogenous estrogen endometrium adenocarcinoma
obestity is a risk factor for... endometrium adenocarcinoma
nulliparous (blank)
menarche (blank)
menopause (blank)
dilation and curettage (blank)
hysterectomy (blank)
adjuvant therapy endometrium adenocarcinoma
ovarian cyst (1) defn (2) causes 3x (3) symptoms (4) big/small cyst? poly?single? easily confused with cancer (1) follicules filled with fluid (2) 1follicles -> cyst 2cystic corpora lutea 3inclusion of surface cells (3) asymptomatic (4) small, single -- easily confused with cancer
unruptured follicles ovarian cyst
follicular cysts ovarian cyst
cystic corpora lutea ovarian cyst
inclusion of ovary surface cells ovarian cyst
Polycystic ovary syndrome (1) defn (2) symptoms (3) consequence (1) hormone bad (2) no M (3) infertility
adrenal kidney
Ovarian neoplasm (1) rate (2) types 3x (3) risk factors (1) most death f ; 2nd common f reprof (2) surface, germ, stromal (3) ovarian dysgenesis, mutation BRCA1 BRCA2
What cancer is the second most common group in female reprod tract? ovarian
What cancer has highest mortality of female reproductive tract? ovarian
Is ovarian cancer common in young female? No
ovarian dysgenesis (blank)
BRCA1 & BRCA2 (blank)
Is oral contraceptives linked to ovarian cancers? No
Surface epithelial tumors @ cervix (1) rate amg cervix cancer (2) types 5x (1) highest 70% (2) serous, mucinous, endometrioid, clear cell, transitional cell
Which is the most common ovarian cancer? Surface?Germ?Stromal? surface, 70%
serous epithelial tumor (1) secretion? (2) appearance (3) grading (blank)
mucinous epithelial tumor (1) secretion? (2) appearance (3) grading (blank)
endometriod epithelial tumor (1) secretion? (2) appearance (3) grading (blank)
Germ cell tumor @ cervix (1) rate (2) risk group (1) 20% (2) young f
what tumor will contain fat, hair and teeth/bone? ovarian teratoma
Teratoma (female) (blank)
Immature teratoma (female) (blank)
sebaceous material (blank)
dermoid cysts (blank)
tumor of germ cells developed into neural tissues (blank)
Fibroma (blank)
fibroblast (blank)
Thecoma (blank)
Theca cells spindle cells - produce estrogen
spindle cells Theca cells - produce estrogen
Granulosa cell tumor granulosa cell
Granulosa cell produce estrogen
4 Causes of infertility (blank)
Asherman's syndrome (blank)
ectopic pregnancy rupture
trophoblast cells epith lining of placental villi
placenta accreta (blank)
placental villi (blank)
placenta previa (blank)
toxemia (blank)
preeclampsia (blank)
eclampsia (blank)
Gestational trophoblastic disease (GTD) (blank)
Hydatidiform mole (1) cause (2) consequence chorionic villi - no fetal movement, high hCG
hydropic degeneration (blank)
chorionic villi disease (blank)
complete mole no fetus / 46xx, all pateranl
incomplete mole little fetus / 69 fmm
Choriocarcinoma highly malignant, treat with methotrexate
methotrexate Choriocarcinoma
What is abortion? <500 g , 20wks
Rate of Spontaneous abortions 1/3 of all preg
complete abortion (blank)
incomplete abortion (blank)
missed abortion (blank)
threatened abortion some live, some die
Endometriosis (blank)
chocolate cyst (blank)
Created by: subaru
 

 



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